What is CRON? - 18% more food?

[Guest guest]

I am still thinking about the paper by Mattson that we discussed

recently (http://snipurl.com/4d7w). In particular, it seems to me

that the CR mice eat more than the ad libitum (AL) mice on a weight

basis.

According to the paper, CR mice received 60% of the weight of the food

eaten by AL mice. As a consequence, the growth of the CR mice was

stunted and adult CR mice weighed 49% less than the AL mice. So, if

the AL mice were getting F grams of food for a body weight of W, the

CR mice were getting 0.6 F grams of food for a body weight of 0.51 W.

Dividing 0.6 F by 0.51 W, we get 1.18 food/weight for the CR mice. To

me this means that the CR mice were getting 18% more food on a weight

basis than the AL mice.

If CRON is about calories, calories, calories, it seems to me that CR

mice are eating more than their share.

Tony