Guest guest Posted September 27, 2004 Report Share Posted September 27, 2004 Below ----- Original Message ----- From: jwwright Sent: Monday, September 27, 2004 8:11 AM Subject: [ ] homocysterine Rather than pursue this, I suggest everyone interested get theirs tested and do what the doc prescribes. It's a medical issue created probably genetically. My homocysteine was about 13. At my doctor's suggestion, I began taking about 3 milligrams (actually 3200 mcg's) a day of folacin in the form of lef's product. This also gave me 1.2 mg's b12. I also got about 50 mg's of b6 from another source. More b6 than I wanted. The effect was that my homocysteine levels dropped to a reading that varies from just over 8 (7 once) to 8 or 9. I have since reduced the supplements to about 1.2 gms of folacin and 300 mcg of b12. B6 remains the same. Homocysteine is still below 8 to just below 9. I was happy, my doctor was happy. I especially like the fact that the treatment is cheap and effective. ED S Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 Thanks, Ed, that's the first test and treatment I've heard about. Was the test in response to a symptom or routine evaluation? Regards. ----- Original Message ----- From: Ed Sullivan Sent: Monday, September 27, 2004 2:11 PM Subject: Re: [ ] homocysterine Below ----- Original Message ----- From: jwwright Sent: Monday, September 27, 2004 8:11 AM Subject: [ ] homocysterine Rather than pursue this, I suggest everyone interested get theirs tested and do what the doc prescribes. It's a medical issue created probably genetically. My homocysteine was about 13. At my doctor's suggestion, I began taking about 3 milligrams (actually 3200 mcg's) a day of folacin in the form of lef's product. This also gave me 1.2 mg's b12. I also got about 50 mg's of b6 from another source. More b6 than I wanted. The effect was that my homocysteine levels dropped to a reading that varies from just over 8 (7 once) to 8 or 9. I have since reduced the supplements to about 1.2 gms of folacin and 300 mcg of b12. B6 remains the same. Homocysteine is still below 8 to just below 9. I was happy, my doctor was happy. I especially like the fact that the treatment is cheap and effective. ED S Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 below ----- Original Message ----- From: jwwright Sent: Tuesday, September 28, 2004 7:38 AM Subject: Re: [ ] homocysterine Thanks, Ed, that's the first test and treatment I've heard about. Was the test in response to a symptom or routine evaluation? Regards. Ed replies: It was at my first review of my first blood tests with new Doc, Dr. Greg Coodley of Portland, Oregon. I had just learned about homocysteine, and he included the test at my request. I had to research to find a range of satisfactory levels, and I believe I found it on LEF's site. Long time ago. Greg knew about the work that had been done. However, his first comment was that it pretty much an average level, and not worry about it. Since the average guy dies of heart disease, and there's some Alzheimer's in my family, I told him I wanted it lower, and he responded with the recommendations, which I followed successfully. LEF sells the folacin b12 combination. It's very inexpensive. Ed Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 FYI: Pizzorno: Textbook of Natural Medicine, 2nd ed., "It has been known for over 25 years that inborn errors of homocysteine metabolism result in high levels of homocysteine in the blood and severe atherosclerotic disease. We now know that, even within the range which is considered normal (4–16 µmol/L), there is a graded increase in risk for CAD. In a study of 304 patients with CAD vs. controls, the odds ratio for CAD increased as plasma homocysteine increased, even within the normal range. A 5 µmol/L increase in plasma homocysteine was correlated with an increase in the odds ratio of 2.4 (P< 0.001), with no “threshold effect”.[35] A review of a number of studies found that mild hyperhomocysteinemia after a methionine load test occurs in 21%, 24%, and 32% of patients with CAD, cerebro-vascular disease, and peripheral vascular disease, respectively.[43] Another group of researchers found the incidence of hyperhomocysteinemia (>14 µmol/L by their definiion) in a group of 1,160 elderly (ages 67–96) individuals, in the Framingham Heart Study, to be 29.3%. The study also indicated that plasma homocysteine levels increase with age.[38] 35. K, Mayer E, D et al. Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. Circulation 1995; 92: 2825–2830 38. Selhub J, Jacques P, Bostom A et al. Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. N Engl J Med 1995; 332: 286–291" FWIW, just found this new book: Rakel: Integrative Medicine, 1st Edition, Chapter 85 - The DASH Diet Rakel M.D. "WHAT IS THE DASH DIET? DASH stands for Dietary Approaches to Stop Hypertension. It consists of a type of diet that has been found to help lower blood pressure[1] as well as homocysteine levels.[2] It is a way of eating that is low in animal and dairy fat and rich in fruits and vegetables. It is a well-balanced diet that can be followed by everyone to help lead a healthy lifestyle ( Table 85–1 ). WHAT IS DIFFERENT ABOUT THIS DIET? The DASH diet can be most closely compared with a Mediterranean-type diet. To summarize, it consists of foods that are • High in fruits and vegetables • Low in dairy, animal meat, and saturated fat • High in nuts, seeds, and beans • Low in snacks and sweets " Regards. ----- Original Message ----- From: Ed Sullivan Sent: Tuesday, September 28, 2004 11:39 AM Subject: Re: [ ] homocysterine below ----- Original Message ----- From: jwwright Sent: Tuesday, September 28, 2004 7:38 AM Subject: Re: [ ] homocysterine Thanks, Ed, that's the first test and treatment I've heard about. Was the test in response to a symptom or routine evaluation? Regards. Ed replies: It was at my first review of my first blood tests with new Doc, Dr. Greg Coodley of Portland, Oregon. I had just learned about homocysteine, and he included the test at my request. I had to research to find a range of satisfactory levels, and I believe I found it on LEF's site. Long time ago. Greg knew about the work that had been done. However, his first comment was that it pretty much an average level, and not worry about it. Since the average guy dies of heart disease, and there's some Alzheimer's in my family, I told him I wanted it lower, and he responded with the recommendations, which I followed successfully. LEF sells the folacin b12 combination. It's very inexpensive. Ed Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 For reference only: I didn't post it, because I didn't want folks to think I'm "treating" anything. Pizzorno is just another POV. Pizzorno: Textbook of Natural Medicine, 2nd ed., Therapeutic approach Supplements • Folinic acid: 800 mcg t.i.d. • Methylcobalamin: 800 mcg t.i.d. • Pyridoxal 5´-phosphate: 20 mg t.i.d. • Betaine (trimethylglycine): 1,200 mg t.i.d. • N-acetylcysteine: 500 mg t.i.d. Regards. ----- Original Message ----- From: Ed Sullivan Sent: Tuesday, September 28, 2004 11:39 AM Subject: Re: [ ] homocysterine below ----- Original Message ----- From: jwwright Sent: Tuesday, September 28, 2004 7:38 AM Subject: Re: [ ] homocysterine Thanks, Ed, that's the first test and treatment I've heard about. Was the test in response to a symptom or routine evaluation? Regards. Ed replies: It was at my first review of my first blood tests with new Doc, Dr. Greg Coodley of Portland, Oregon. I had just learned about homocysteine, and he included the test at my request. I had to research to find a range of satisfactory levels, and I believe I found it on LEF's site. Long time ago. Greg knew about the work that had been done. However, his first comment was that it pretty much an average level, and not worry about it. Since the average guy dies of heart disease, and there's some Alzheimer's in my family, I told him I wanted it lower, and he responded with the recommendations, which I followed successfully. LEF sells the folacin b12 combination. It's very inexpensive. Ed Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 below Pizzorno: Textbook of Natural Medicine, 2nd ed., the odds ratio for CAD increased as plasma homocysteine increased, even within the normal range. A 5 µmol/L increase in plasma homocysteine was correlated with an increase in the odds ratio of 2.4 (P< 0.001), with no “threshold effect”.[35] A review of a number of studies found that mild hyperhomocysteinemia after a methionine load test occurs in 21%, 24%, and 32% of patients with CAD, cerebro-vascular disease, and peripheral vascular disease, respectively.[43] Another group of researchers found the incidence of hyperhomocysteinemia (>14 µmol/L by their definiion) in a group of 1,160 elderly (ages 67–96) individuals, in the Framingham Heart Study, to be 29.3%. The study also indicated that plasma homocysteine levels increase with age.[38] This is new information to me. I was content with the 8+- range because that's about the range of the elder okinawans. Since I'm still fat, and since McCully said (I think) that homocysteine decreases with bodyfat levels (I'll have to check that), I'm hoping that I can reduce the H levels even more. Thanks, Ed Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 28, 2004 Report Share Posted September 28, 2004 Below, ----- Original Message ----- From: jwwright Sent: Tuesday, September 28, 2004 1:51 PM For reference only: I didn't post it, because I didn't want folks to think I'm "treating" anything. Pizzorno is just another POV. Pizzorno: Textbook of Natural Medicine, 2nd ed., Therapeutic approach Supplements • Folinic acid: 800 mcg t.i.d. • Methylcobalamin: 800 mcg t.i.d. • Pyridoxal 5´-phosphate: 20 mg t.i.d. • Betaine (trimethylglycine): 1,200 mg t.i.d. • N-acetylcysteine: 500 mg t.i.d. I tried the trimethylglycine at a somewhat higher level for about 6 months. at Saul's suggestion. Didn't make any difference. I dropped it. Still got some around here somewhere. Haven't tried N-acetylcysteine. I really need to work harder on calories, calories, calories... Ed Quote Link to comment Share on other sites More sharing options...
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