Re: Correct dose for LDN?

[Guest guest]

Good question... I have been on LDN for 10 months. When we first started exchanging progress reports on this site ,it seems that those with RR get the most benefit. It makes sense because once they remit and return to a "normal state" and take LDN there should be no relapse again.

Dr, B had told me that I may regain only what I had lost in the last 3 months and nothing more. For those of us on LDN ONLY , this seemed to happen in the first 4-6 weeks. From that point on, I would remain stable.( I am either SP or PP not sure) ..Dr. B was correct.

My observation from friends...improvement seems to take a longer if on Copaxone

As far as dosage goes, each person must find what their body reacts to. There are some on 1.5 and some on 6mgs.

Many have started on 3 for a month and then moved to 4.5 comfortably and felt the difference. I , personally am the rare case (2 out of 350) patient who Dr. B has upped to 6mgs. I have not gained anything more except that now I sleep thru the night therefore function better in the day.

The placebo effect would have worn out by now, 10 months on LDN and no progression boosts my outlook on my future . This has been God sent to us all and I wish your wife only wonderful times from now on. Kiki

[Guest guest]

Hi - Kind of hcesident to answer your post because I have only

been on LDN for about 35 days. But I feel GREAT, and am hoping I am

one of the " few " who get fantastic results. So here goes:

You did not say how long your wife has been on LDN, but I have to

caution you, don't expect too much improvement too soon. This is

something that needs time to work. Also, I really think from reading

everyone's posts that a lot depends on what the individual

circumstances are for each of us. I have very mild MS symptoms, and

was just recently dx'ed, only maybe 10 years of mild damage and so

my experience is much different than someone who is fighting years

and years of serious damage.

I think everyone would like to know why some get better results

quicker than others. Hopefully sometime in the future, a clinical

trial will give us some of those answers. For me, I think it has a

lot to do with diet, attitude and probably enviromental issues. The

million dollar question I guess. I would like to see everyone get

the best results possible. If you discover a common factor, I am

sure we would all be mondo interested.

From reading all of what everyone posts, the higher dose you can

tolerate (up to 4.5) the better. At least those who have direct

contact with Dr. B say that. And if you can take that much without

problem, I would think one would be silly not to. I myself have

recently increased from 3.0 to 4.5 and am noticing additional

benefits from the higher dose. And of course, we all want all the

benefit we can get. But it does seem to have some relationship to

the type (RRMS, SPMS, PPMS) of MS one has as to if that holds true.

I think a lot of the PPMS and SPMS people really feel that less is

more. But for RRMS, I do think you have better chances of best

improvement with the highest dosage you can stand.

As far as the placebo effect, well - I may be able to fool myself

into thinking I am feeling better, possibly even into being better

able to move, balance whatever. But I really doubt I could convince

my bladder to stop waking me up at night to " go " several times. I

don't think I have that much control But indeed - last night I slept

6.5 hours without getting up once. I have not done that in years!!!

So, no I don't think this is a placebo for me.

Anyhow, I hope you get a lot of responses to your post, and that you

find some of those answers to share with the rest of us - and best

wishes to your wife, may she get wonderful benefits from the LDN.

Cinders