Re: Re: LDN -URGENCY/why trial

[Guest guest]

If I crave chocolate because it raises endorphins then it follows that LDN

is successfully raising my endorphins since I do not crave chocolate at all

anymore...

----- Original Message -----

From: " yashagrawal " <yashagrawal@...>

<low dose naltrexone >

Sent: Saturday, May 22, 2004 5:12 AM

Subject: [low dose naltrexone] Re: LDN -URGENCY/why trial

> Gerald:

> LDN is fairly readily available so everyone who thinks

> independently can get it. However a trial is definitely needed for

> the following reasons.

> 1. There are thousands of poor souls who in their misguided wisdom,

> or perhaps due to their better understanding of how things work,

> absolutely refuse to take LDN. They will need a trial to convert

> them. It would be unethical to leave them behind.

> 2. LDN may have a placebo effect. The human mind is a very

> powerful thing but it can be tricked. Infact, it has been proven

> that a 30-35 % response rate is typical for a placebo effect. Due to

> this, there is a school of thought that believes all ABCR's are just

> placebos. LDN is believed to have a higher response rate, but how

> will we know without a trial ?.

> 3. There are many hypothesis as to how LDN might work. One

> possibility is that it elevates endorphins, if you think about it,

> endorphins have mood elevating properties. Could it be that we feel

> good because of the endorphin pulse, which leads to a better frame

> of mind, low stress and better recovery ?. Note, good quality

> chocolates elevate endorphins. That is the reason some people eat

> them. They crave endorphins.

> 4. If a trial shows that LDN works, it will spawn intense research.

> Big money will be spend in understanding the mechanisms, this will

> lead to newer better drugs.

>

> For these and other reasons, a trial is necessary.

>

> Yash

>

>

> > Hi All!

> >

> >

> >

> > It`s been heartening recently to see all this energy being put

> towards causing LDN to become more widely appreciated & more easily

> available: However, I`m wondering if there is another tack which

> could be developed to help bring this about? -So far as I am aware,

> the focus at present seems to be on how bring about controlled

> tests, presumably with a number of folks taking LDN & a number

> taking a placebo....well!..... - hands up all those LDN users who

> would like to spend some months (-or years even?) in the placebo

> group?!!!!!!!! -not many, I imagine!

> >

> >

> >

> > In my view, knowingly to place people who, like us, have a

> degenerative, or in some cases, an immediatally life threatening dis-

> ease, on a placebo, when it is know that LDN " works " would be

> clearly unethical.

> >

> > Further, why is it necessary? LDN is already known by us, its

> users, to be effective, safe, easy to use, inexpensive & to have

> little if any in the way of negative side effects: By all accounts,

> completely outclassing the currently approved, (obscenely expensive)

> medications! Surely, with a drug that is already accepted by the FDA

> as safe at over 10-20 times the LDN dosage, the safety issue has

> already been resolved!

> >

> > Regarding it`s effectiveness, seems to me that are already a lot

> of us who can & do confirm that! -I imagine that I am not the only

> one who feels there is something wrong with a system that is so

> insensitive that it can`t or won`t be more responsive to our

> enthusiastic testimonies? The easy dismissal of such a large body of

> consistent experiental first hand knowledge as merely " anecdotal "

> seems almost insulting & is certainly complacent, insensitive &

> unwise! - Prehaps we need to focus more on way(s) of " Speaking with

> one voice. " -Could it be that it would be more appropiate for us to

> focus on getting a (loud!) message out that makes these points

> widely, clearly & strongly, rather than meekly calling for tests, as

> though we are ourselves are unsure of the real value of

> LDN?!!

>

> >

> > -WE ARE THE TEST

> RESULTS!!!

> >

> > ( & I think that there are enough of us to

> be heeded!)

> >

> >

> >

> > There is little, if anything to be lost & potentially a great deal

> to be gained by very many people who, RIGHT NOW are in the throes

> of degenerative & terminal dis-eases, people who cannot afford to

> wait while some basically unnecessary, time consuming procedures are

> carried out!

> >

> >

> >

> > If any of these points do strike a chord, & you feel that it`s

> appropiate, (I`m thinking especially of those who have recently

> shown yourselves to be such capable thinkers/letter writers/

> organizers/ developers/ movers & shakers/DO-ERS, etc.etc.!), prehaps

> you could consider how this might be carried out effectively?

> >

> > -Do we LDN users (-ie, the ones who actually,experientially know

> what it does!) need to be focused & organized more as an

> information disseminating & motivating " body " ?

> >

> >

> >

> > Thank you for giving these thoughts your attention.

> >

> >

> >

> > Best wishes to you all,

> >

> >

> >

> > Gerald (-SPMS)

>

>

>

>

>

>

[Guest guest]

Interesting! Ten weeks ago before starting on LDN I was a chocoholic

but now my desire for chocolate is definitely decreasing.

wrote:

If I crave chocolate because it raises endorphins then it follows that

LDN

is successfully raising my endorphins since I do not crave chocolate at

all

anymore...

-- .

,-._|\ Covington / Oz \ \_,--.x/ v

[Guest guest]

Yes that is very interesting and something I really never considered but now for the very first time in my life(and I do mean that)I can put down a chocolate bar after only one or two bites and not even miss it!

I used to get my energy to get through the day from a steady diet of Snickers or Oreos anything chocolate was good.

This is a side affect but it is a good one.

Reg

-------Original Message-------

From: low dose naltrexone

Date: 05/22/04 10:02:01

low dose naltrexone

Subject: Re: [low dose naltrexone] Re: LDN -URGENCY/why trial

Interesting! Ten weeks ago before starting on LDN I was a chocoholic but now my desire for chocolate is definitely decreasing. wrote:

If I crave chocolate because it raises endorphins then it follows that LDNis successfully raising my endorphins since I do not crave chocolate at allanymore...-- .

,-._|\ Covington / Oz \ \_,--.x/ v

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