Guest guest Posted October 14, 2009 Report Share Posted October 14, 2009 It can take literally years for levels of B12 to deplete in the body. We who have injections arrange for any testing to be done just prior to an injection, anything from 1 week to 3 montha according to frequency of dose. For those on sublinguals or regular daily doses, probably a couple of weeks would do, and just make allowance for the fact that you are taking a supplement, Regarding the higher level of nearly 2,000 ng/L I suspect that you had probably taken your dose for the day and hadn't had a break from taking them? If you are concerned you could drop your dose a bit, but there is no harm in high levels; just unnecessary rxpense B12 is used to combat cyanide poisoning and also smoke inhalation. it is given in 5 GRAM injections, this dose is apparently equivalent to 198 years of twice weekly injections, and I understand the only side effects are a skin rash and discolouration of plasma/urine. Ginny B > If you are supplementing B12 and want to get it tested, how long should you stop taking the supplement before the blood test? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 14, 2009 Report Share Posted October 14, 2009 save as pdf LinkVit B12 cyanocobalamin is about the safest way to sequester cyanide in the body. I wonder how may labs/doctors/pharmacies/ambulances carry 5gm shots of vit B12 (methyl-cobalamin etc)http://www.ajcn.org/cgi/reprint/48/3/852.pdf--- In thyroid treatment , "ginnybrown75" <ginnybrown75@...> wrote:>> It can take literally years for levels of B12 to deplete in the body.> We who have injections arrange for any testing to be done just prior> to an injection, anything from 1 week to 3 montha according to> frequency of dose.> > For those on sublinguals or regular daily doses, probably a couple> of weeks would do, and just make allowance for the fact that you are > taking a supplement,> > Regarding the higher level of nearly 2,000 ng/L I suspect that you> had probably taken your dose for the day and hadn't had a break> from taking them? If you are concerned you could drop your dose a bit, but there is no harm in high levels; just unnecessary rxpense> > B12 is used to combat cyanide poisoning and also smoke inhalation. it is given in 5 GRAM injections, this dose is apparently equivalent to 198 years of twice weekly injections, and I understand the only side effects are a skin rash and discolouration of plasma/urine.> > Ginny B> > > > > > If you are supplementing B12 and want to get it tested, how long should you stop taking the supplement before the blood test?> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2009 Report Share Posted October 15, 2009 Perhaps you should contact the Head office of the Ambulance Service Bob and put this question to them. Luv - Sheila save as pdf Link Vit B12 cyanocobalamin is about the safest way to sequester cyanide in the body. I wonder how may labs/doctors/pharmacies/ambulances carry 5gm shots of vit B12 (methyl-cobalamin etc) http://www.ajcn.org/cgi/reprint/48/3/852.pdf > > > If you are supplementing B12 and want to get it tested, how long should you stop taking the supplement before the blood test? > No virus found in this incoming message. Checked by AVG - www.avg.com Version: 8.5.421 / Virus Database: 270.14.15/2434 - Release Date: 10/13/09 19:11:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2009 Report Share Posted October 15, 2009 Perhaps you should contact the Head office of the Ambulance Service Bob and put this question to them. Luv - Sheila save as pdf Link Vit B12 cyanocobalamin is about the safest way to sequester cyanide in the body. I wonder how may labs/doctors/pharmacies/ambulances carry 5gm shots of vit B12 (methyl-cobalamin etc) http://www.ajcn.org/cgi/reprint/48/3/852.pdf > > > If you are supplementing B12 and want to get it tested, how long should you stop taking the supplement before the blood test? > No virus found in this incoming message. Checked by AVG - www.avg.com Version: 8.5.421 / Virus Database: 270.14.15/2434 - Release Date: 10/13/09 19:11:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2009 Report Share Posted October 15, 2009 > > Vit B12 cyanocobalamin is about the safest way to sequester cyanide in> the body. I wonder how may labs/doctors/pharmacies/ambulances carry 5gm> shots of vit B12 (methyl-cobalamin etc) Many thanks for that, Bob. Must admit, however, that most of the article went straight over my head. It is just too technical for my already confused brain. I was about to order some B12 drops from 'Metabolics', only to discover that there are all those different 'cobalamins' to complicate my life.... I phoned 'Metabolics', but they tell me they are only a sales team and can't give advice, apparently I would need some special testing to find out whether Adenosyl- , Cyano- , Hydroxy- or Methyl-cobalamin would be the right one for my body All I want is to boost my B12 levels and those of my husband. Can somebody on here please help me out? I remember Sheila talking about sublingual B12 to buy over the counter or from a website.... which one shall I go for and where would I buy those sublingual ones? Many thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 15, 2009 Report Share Posted October 15, 2009 THE METABOLIC ROLE OF VITAMIN B12 There are several different forms of vitamin B12, or cobalamins, but only two cobalamins are metabolically active: methyl- and adenosylcobalamin. The common feature for all cobalamin forms is a corrin ring with a central cobalt atom. The commercially available forms, used for treating deficiency: hydroxo- (OHCbl) and cyanocobalamin (CnCbl), are converted within the body into the active forms. http://www.active-b12.com/b12-deficiency/general.php As I understand it Adenosylcobalimin and Country Life Active B12 Dibencozide are the same thing. This is available in 3.000 mcg sublinguals from I-herb or Bigvits in the UK. which would probably be a bit too much for normal low B12, Methylcobalimin is the other active one, both Jarrows and Solgar do sublinguals. 2000 or 1000 mcg The Hydroxo and Cyano are usually in the form of injections and have to be converted in the liver, though I think some cyano tablets may be available. It really is a case of try it and see as to which would suit best for each person, but the best place to start would be Methycobalimin Subs. Ginny B > I was about to order some B12 drops from 'Metabolics', only to discover > that there are all those different 'cobalamins' to complicate my > life.... some special testing > to find out whether Adenosyl- , Cyano- , Hydroxy- or Methyl-cobalamin > would be the right one for my body Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2009 Report Share Posted October 16, 2009 If those patients unable to convert T4 to the active T3 in the liver and other thyroid hormone receptors around the body, is it also possible that this might apply to the conversion of the 'inactive' OHCb and CnCbl into the active forms too? Luv - Sheila There are several different forms of vitamin B12, or cobalamins, but only two cobalamins are metabolically active: methyl- and adenosylcobalamin. The common feature for all cobalamin forms is a corrin ring with a central cobalt atom. The commercially available forms, used for treating deficiency: hydroxo- (OHCbl) and cyanocobalamin (CnCbl), are converted within the body into the active forms. http://www.active-b12.com/b12-deficiency/general.php It really is a case of try it and see as to which would suit best for each person, but the best place to start would be Methycobalimin Subs. Ginny B Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2009 Report Share Posted October 16, 2009 I believe this is possible, and may be why some people respond to supplements better than others. But those that go straight into the bloodstream such as injections and sublinguals should bypass this conversion process provided it is methyl or adenosyl (Dibencoizide) I know of no studies on this Ginny B > If those patients unable to convert T4 to the active T3 in the liver and > other thyroid hormone receptors around the body, is it also possible that > this might apply to the conversion of the 'inactive' OHCb and CnCbl into the> active forms too? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2009 Report Share Posted October 16, 2009 ***.... Methylcobalimin is the other> active one, both Jarrows and Solgar do sublinguals. 2000 or 1000 mcg> It really is a case of try it and see as to which would suit best for> each person, but the best place to start would be Methycobalimin Subs. Thank you very much for that, Ginny - I will file this info. I have now ordered the subliguals from Solgar, which is a Methylcobalamin, and I'll see how I get on with those. Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2009 Report Share Posted October 16, 2009 Would a good spoon of Marmite not give us all the B12 & other Bs we need? I used to have a spoon every morning for years. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 16, 2009 Report Share Posted October 16, 2009 The daily recommended dosages are based on the amount you need to avoid deficiency diseases. Doctors have found that high doses of B12 can help with various conditions. These are way above the recommended daily amounts. I think the only way you can tell whether a high dose of B12 might be of benefit is to try it. Miriam > > Would a good spoon of Marmite not give us all the B12 & other Bs we need? > > I used to have a spoon every morning for years. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 17, 2009 Report Share Posted October 17, 2009 Hmm, that exlains my sudden urge to hump a stranger's legRe the taste, I wouldn't eat it on toast, but if you take a spoon full & wash it down with water or juice, you don't taste it.Ian> >> > Would a good spoon of Marmite not give us all the B12 & other Bs we> need?> > > > > Hi Ian,> > Funnily enough, my vet has recommended a daily spoon full of Marmite for> my dog (who's got Endocrinopathy)... - dog loves it !!> > I, however, am one of those who hates the taste <G> . Although it> probably will give you quite a few of the other B vits, I have doubts to> say the same for Vit B12. That would most likely get destroyed by the> stomach acids... still, if you like the stuff, go for it []> > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 18, 2009 Report Share Posted October 18, 2009 It really depends whether you have a serious B12 deficiency and what is causing it. I have just been reading " Could it be B12? " by Sally Pacholok and Stuart. They say that the serum B12 test is unreliable, and that you need two other tests called urinary MMA and a test of homocysteine levels. If homocysteine is high it is most probably because of B12 deficiency, regardless of the serum B12 level. In the same way that there are many stages in the journey of thyroid hormones to the cells, there are many different things that can go wrong with the processing of B12. If you have one of these more complex problems, taking standard B12 supplements, they say, is like " trying to fill an empty swimming pool with a teaspoon of water each day. " Miriam > > Would a good spoon of Marmite not give us all the B12 & other Bs we need? > > I used to have a spoon every morning for years. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 19, 2009 Report Share Posted October 19, 2009 > > > > > > > > > > Hi Ian, > > > > Funnily enough, my vet has recommended a daily spoon full of Marmite > for > > my dog (who's got Endocrinopathy)... - dog loves it !! > > > >, what symptoms does your dog have? I know dogs have thryoid problems usually underactive. I am worried about my collie x who seems to tire easily... Thanks Isabel Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 19, 2009 Report Share Posted October 19, 2009 There is a new test called " Holo-TC " which measures the amount of Active B12 (Holotranscobalimin)in the blood, but is not available to us yet. Only 25% of the B12 in the blood is available to us as active.This explains a bit: http://www.active-b12.com/active-b12-introduction/why-use-active-b12.php Note the little blue window at the bottom of the page which states: There is a grey zone between 151-300 pmol/L B12 where there is likely to be misclassification of B12 status if relying on total serum B12 alone. Ginny B > > It really depends whether you have a serious B12 deficiency and what is causing it. > > I have just been reading " Could it be B12? " by Sally Pacholok and Stuart. They say that the serum B12 test is unreliable, and that you need two other tests called urinary MMA and a test of homocysteine levels. If homocysteine is high it is most probably because of B12 deficiency, regardless of the serum B12 level. [Edit Abbrev Mmod] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 1, 2010 Report Share Posted February 1, 2010 Most definitely. Your B12 level should be AT THE TOP OF THE REFERENCE RANGE. Luv - Sheila I see people are talking about B12 levels and injections and wondered if I should ask my GP if he would consider B12 injections for me, as my B12 level is 284.Does anyone think its worth me asking and does anyone have them already and has it helped? I knew someone who had them and she said it helped her and she knows when she needs another one,as she feels very tired. Best wishes Sharon No virus found in this incoming message. Checked by AVG - www.avg.com Version: 8.5.432 / Virus Database: 271.1.1/2650 - Release Date: 01/31/10 06:39:00 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 3, 2011 Report Share Posted August 3, 2011 Hi Ian: This book will give you those answers and some great info on all supplements and up to date research. http://www.amazon.com/Drug-Muggers-Medications-Essential-Nutrients--/dp/16052941\ 60/ref=sr_1_1?s=books & ie=UTF8 & qid=1312386326 & sr=1-1 Cheers, JOT > Does anyone know what are sensible figures for a B Complex? > > Ian > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 13, 2011 Report Share Posted August 13, 2011 Do most of you know how much B12 taken orally is needed to correct a deficiency? My doc says 500 mc. is enough. The shots caused heart palpitations & extreme anxiety. Doc is refusing to run bloodwork to make sure it's not anything else. I'm sorry, but I can't handle an MRI. Kathy Quote Link to comment Share on other sites More sharing options...
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