Re: LDN -URGENCY/why trial

[Guest guest]

Gerald:

LDN is fairly readily available so everyone who thinks

independently can get it. However a trial is definitely needed for

the following reasons.

1. There are thousands of poor souls who in their misguided wisdom,

or perhaps due to their better understanding of how things work,

absolutely refuse to take LDN. They will need a trial to convert

them. It would be unethical to leave them behind.

2. LDN may have a placebo effect. The human mind is a very

powerful thing but it can be tricked. Infact, it has been proven

that a 30-35 % response rate is typical for a placebo effect. Due to

this, there is a school of thought that believes all ABCR's are just

placebos. LDN is believed to have a higher response rate, but how

will we know without a trial ?.

3. There are many hypothesis as to how LDN might work. One

possibility is that it elevates endorphins, if you think about it,

endorphins have mood elevating properties. Could it be that we feel

good because of the endorphin pulse, which leads to a better frame

of mind, low stress and better recovery ?. Note, good quality

chocolates elevate endorphins. That is the reason some people eat

them. They crave endorphins.

4. If a trial shows that LDN works, it will spawn intense research.

Big money will be spend in understanding the mechanisms, this will

lead to newer better drugs.

For these and other reasons, a trial is necessary.

Yash

> Hi All!

>

>

>

> It`s been heartening recently to see all this energy being put

towards causing LDN to become more widely appreciated & more easily

available: However, I`m wondering if there is another tack which

could be developed to help bring this about? -So far as I am aware,

the focus at present seems to be on how bring about controlled

tests, presumably with a number of folks taking LDN & a number

taking a placebo....well!..... - hands up all those LDN users who

would like to spend some months (-or years even?) in the placebo

group?!!!!!!!! -not many, I imagine!

>

>

>

> In my view, knowingly to place people who, like us, have a

degenerative, or in some cases, an immediatally life threatening dis-

ease, on a placebo, when it is know that LDN " works " would be

clearly unethical.

>

> Further, why is it necessary? LDN is already known by us, its

users, to be effective, safe, easy to use, inexpensive & to have

little if any in the way of negative side effects: By all accounts,

completely outclassing the currently approved, (obscenely expensive)

medications! Surely, with a drug that is already accepted by the FDA

as safe at over 10-20 times the LDN dosage, the safety issue has

already been resolved!

>

> Regarding it`s effectiveness, seems to me that are already a lot

of us who can & do confirm that! -I imagine that I am not the only

one who feels there is something wrong with a system that is so

insensitive that it can`t or won`t be more responsive to our

enthusiastic testimonies? The easy dismissal of such a large body of

consistent experiental first hand knowledge as merely " anecdotal "

seems almost insulting & is certainly complacent, insensitive &

unwise! - Prehaps we need to focus more on way(s) of " Speaking with

one voice. " -Could it be that it would be more appropiate for us to

focus on getting a (loud!) message out that makes these points

widely, clearly & strongly, rather than meekly calling for tests, as

though we are ourselves are unsure of the real value of

LDN?!!

>

> -WE ARE THE TEST

RESULTS!!!

>

> ( & I think that there are enough of us to

be heeded!)

>

>

>

> There is little, if anything to be lost & potentially a great deal

to be gained by very many people who, RIGHT NOW are in the throes

of degenerative & terminal dis-eases, people who cannot afford to

wait while some basically unnecessary, time consuming procedures are

carried out!

>

>

>

> If any of these points do strike a chord, & you feel that it`s

appropiate, (I`m thinking especially of those who have recently

shown yourselves to be such capable thinkers/letter writers/

organizers/ developers/ movers & shakers/DO-ERS, etc.etc.!), prehaps

you could consider how this might be carried out effectively?

>

> -Do we LDN users (-ie, the ones who actually,experientially know

what it does!) need to be focused & organized more as an

information disseminating & motivating " body " ?

>

>

>

> Thank you for giving these thoughts your attention.

>

>

>

> Best wishes to you all,

>

>

>

> Gerald (-SPMS)