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Re: FYI: Recall Alert

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The FDA is conducting a safety review based on study data suggesting

there may be an increased risk of death from cancer in diabetic patients

using Regranex (becaplermin) Gel, a skin product used to heal leg and

foot ulcers. While the review is ongoing, the FDA recommends healthcare

professionals discuss the potential risks and benefits of using

Regranex with their patients.

This early communication is in keeping with the FDA's commitment to

inform the public about its ongoing safety reviews of drugs. As soon as

this review is complete, the FDA will communicate the conclusions and

recommendations to the public.

Read the complete 2008 FDA Safety Summary, including a link to the FDA

Early Communication About An Ongoing Safety Review regarding this issue

at:

http://www.fda.gov/medwatch/safety/2008/safety08.htm#Regranex

So what type of recall is this?

Jeanetta CPhT BS

Jeanetta Mastron CPhT BS Chemistry <rxjm2002@...> wrote:

PharmacyOneSource.com Drug Shortage, Product Recall & Alert Newsletter.

The FDA issued an Early Communication about recent findings of The

Data Collection on Adverse Events of Anti-HIV Drugs Study. Data

analyses from this study indicate a higher risk of heart attack in

patients infected with HIV-1 who were taking Ziagen (abacavir) or

Videx (didanosine) as part of their drug therapy. The study is a large

observational study of 33,347 HIV-1 infected patients living in North

America, Europe and Australia. Patients in this study are being

followed to evaluate the short and long term adverse effects of

treatment with anti-HIV drugs. FDA continues to evaluate the overall

risks and benefits of abacavir and didanosine. This evaluation may

result in the need to revise labeling for the products. Until the

FDA's review is complete, healthcare professionals should evaluate

the potential risks and benefits of each HIV-1 antiretroviral drug

their patients are taking.

This early communication is in keeping with the FDA's commitment to

inform the public about its ongoing safety reviews of drugs. As soon

as this review is complete, the FDA will communicate the conclusions

and recommendations to the public.

Read the complete 2008 FDA MedWatch Safety Summary, including a link

to the FDA Early Communication About an Ongoing Safety Review

regarding this issue at:

http://www.fda.gov/medwatch/safety/2008/safety08.htm#abacavir

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Once again this is a REAL communication but it is NOT a Recall it is

an Alert! After more research and data the FDA may decide to recall or

issue a black box warning.

One who is in the field should keep an eye open for more possible

alerts or future recalls about this drug.

Hope this helps.

Jeanetta Mastron CPhT BS

Founder/Owner

PharmacyOneSource.com Drug Shortage, Product Recall

& Alert Newsletter.

>

> The FDA issued an Early Communication about recent findings of The

> Data Collection on Adverse Events of Anti-HIV Drugs Study. Data

> analyses from this study indicate a higher risk of heart attack in

> patients infected with HIV-1 who were taking Ziagen (abacavir) or

> Videx (didanosine) as part of their drug therapy. The study is a large

> observational study of 33,347 HIV-1 infected patients living in North

> America, Europe and Australia. Patients in this study are being

> followed to evaluate the short and long term adverse effects of

> treatment with anti-HIV drugs. FDA continues to evaluate the overall

> risks and benefits of abacavir and didanosine. This evaluation may

> result in the need to revise labeling for the products. Until the

> FDA's review is complete, healthcare professionals should evaluate

> the potential risks and benefits of each HIV-1 antiretroviral drug

> their patients are taking.

>

> This early communication is in keeping with the FDA's commitment to

> inform the public about its ongoing safety reviews of drugs. As soon

> as this review is complete, the FDA will communicate the conclusions

> and recommendations to the public.

>

> Read the complete 2008 FDA MedWatch Safety Summary, including a link

> to the FDA Early Communication About an Ongoing Safety Review

> regarding this issue at:

> http://www.fda.gov/medwatch/safety/2008/safety08.htm#abacavir

>

>

>

>

>

>

>

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