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Big news on cause of cell death in PPMS

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This study has located 2 molecules " Located on the surface of most

nerve fibers, Nav.1.6 controls the flow of sodium into the cell,

which in turn triggers the activation of NCX, a molecule that, if

unchecked, imports abnormal levels of calcium into the nerve fiber

that ultimately lead to its death. "

http://www.pharma-lexicon.com/medicalnews.php?newsid=8788

(saw the report on this in the bostoncure.org news alert)

This brought to mind 4AP, now no longer available, which may be a

good thing, because there is other research underway on calcium

flooding of axons to " determine safety limits of drugs such as 4AP,

which may enhance nerve conduction but increase influx of possibly

harmful calcium "

http://www.nationalmssociety.org/Research-Chiu.asp

Now for my amateur question of the day: Calcium and other minerals

are of course hugely important to the body, but can taking them as a

supplement possibly increase this risk of calcium flooding into axons

and killing them?

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