Re: need help with compounding prescriptions please

[Guest guest]

HI Tammi!

I do not know if thre are other pieces of information in your math

problem such as a {C} or concentration of the progesterone powder. But

if the progesterone powder is 100% progesterone then this will work.

a)show all calculations required to compound this suppository

prescription.

I do not see the need to show any calculations! I would say just weigh

out the ingredients. UNLESS as I stated above there is a concentration

of the progesterone powder that you did not include in this scenario.

I am not using ratio/proportion method here, but rather dimensional

analysis or string conversion. Why? because I have to leave my home

right now for most of the day, and it takes a while to do

ratio/proportion on the posts to set it up just right. HTML is not

kind to the set up! But when I get back I will post this same math in

using a ratio/proportion method.

Active Ingredient = progesterone

25mg/supp x 100 suppositories= 2500mg

2500mg x 1gm/1000mg = 2.5 gm

Inactive ingredient = polybase

245gm /100 supp = 2.45 gm/supp 2.45 gm x 1000mg/gm = 2450 mg /supp

b)describe the compounding procedure for this prescription.

Since the recipe or formula is given.

Weigh out the TWO individual ingredients.

Using a mortar and pestle triturate (grind) the WEIGHED powdered

progesterone to a fine powder.

Perform gradual geometric dilutions of the powder to the polybase

Place the compounded mixture in the suppository molds.

Allow to harden.

Wrap individual suppositories.

c)If half a suppository is required for 3 days, how should the

suppositories be divided?

One half suppository for three days ( I am interpreting this to be

one-third of half of the suppository is to be administered to the

patient each of day for three days.)

1/2 suppository for three doses

so 1/2 of the suppository divided by three equals

1/3 of 1/2 = 1/6 of the whole suppository

Each 1/6 of the suppository is to be administered each day for three days.

Once could weigh the suppository and divide it by 6 for the exact same

amount per dose. But I doubt a nurse would do this or have access to

a scale.

Most nurses would divide one supp by 2 then divide one of the halves

by three.

On day four one-half of the suppository would be remaining.

ANY other suggestions out there are welcome! Any compounding experts

(someone who compounds daily?) out there?

I do hope this helps,

Jeanetta Mastron CPhT BS

Founder/Owner of this site

>

> In class we just finished are third week of calculations:dosages. I

> not only knew which formula to use with each problem but also

> understood it and got the correct answers. However. the last

> worksheet she gave us was " critical thinking skills with compounding

> prescriptions. " I actually started the week after they were in

> compounding so I am so lost. Any help with the following would be so

> appreciated.

>

>

> script: progesterone 25mg supp unwrap and insert one supp pr qd

>

> ingredients for 100 suppostories:

> progesterone powder 2.5 gm

> polybase 245 gm

>

> a)show all calculations required to compound this suppository

> prescription.

>

> b)describe the compounding procedure for this prescription.

>

> c)If half a suppository is required for 3 days, how should the

> suppositories be divided?

>

[Guest guest]

You may wish to see some video clips of this:

Files >

5- Tutorial-1 & Study Information >

S11- Compounding Medication Tutorials

Video Clips on Sterile Compounding

There you will find the site addy

Hope this helps you.

Jeanetta Mastron CPhT BS

Founder/Owner

> >

> > In class we just finished are third week of calculations:dosages. I

> > not only knew which formula to use with each problem but also

> > understood it and got the correct answers. However. the last

> > worksheet she gave us was " critical thinking skills with compounding

> > prescriptions. " I actually started the week after they were in

> > compounding so I am so lost. Any help with the following would be so

> > appreciated.

> >

> >

> > script: progesterone 25mg supp unwrap and insert one supp pr qd

> >

> > ingredients for 100 suppostories:

> > progesterone powder 2.5 gm

> > polybase 245 gm

> >

> > a)show all calculations required to compound this suppository

> > prescription.

> >

> > b)describe the compounding procedure for this prescription.

> >

> > c)If half a suppository is required for 3 days, how should the

> > suppositories be divided?

> >

>