Exacerbations while on LDN - what to do?

[Guest guest]

I've been taking ldn, 3.0 mgs nightly for 2 months now. I usually

have what I call 'mini flares' once or twice a year - which " slam-

dunk " me into stuck-in-bed-mode with that indescribable fatigue that

makes it nearly impossible to do anything other than rest, lie in

bed, and rely on others to do the simplest things.

I've felt well on LDN until this week, when I got 'hit' with a flare.

I feel I'm coming out of it but wonder if I should increase the LDN

to 4.5, stay at 3.0 mgs, or ??? Does Dr. B have an article about the

doseages one should take specifically for MS?

I have RR MS, (for 20 years)am not on any of the CRABs, won't do

them, tried Copaxone and got worse and lost weight, had new symptoms

occur while on it that I'd never had before, they stopped when I quit

Copax).

I am a firm believer in LDN even thru this recent flareup - the

stress level has been at an all-time high in my home and I know this

is what brings on most of my flareups.

If anyone can email me about their experiences with having a flareup

while on LDN, if they stopped, changed doseages, etc, I'd appreciate

the feedback. I may not be able to read and reply to each email

immediately as I am fatigued and dealing with neuropathic pain.

Also live in hot Florida, but have been inside in A/C thru out this

exacerbation.

[Guest guest]

Hey hallie -dee,

From one Floridian to another, I just recently got over an exacerbation

while on 3mg since Feb. and yes my stress level was at an all time high as

well! By all means continue taking your LDN and what helped me to control

my stress was exercise and meditation. I've also been dealing with MS for

over 20 years, and as you know dealing with stress is sometimes an

overwhelming thing. I did note that while on LDN, my flair up only lasted a

couple of weeks compared to previous flare ups that stayed with me for

months. Good luck, stay positive and you will bounce back!!

-spms

-----Original Message-----

From: hallie_dee [mailto:Hallie39@...]

Sent: Friday, July 30, 2004 2:31 PM

low dose naltrexone

Subject: [low dose naltrexone] Exacerbations while on LDN - what to do?

I've been taking ldn, 3.0 mgs nightly for 2 months now. I usually have what

I call 'mini flares' once or twice a year - which " slam- dunk " me into

stuck-in-bed-mode with that indescribable fatigue that makes it nearly

impossible to do anything other than rest, lie in bed, and rely on others to

do the simplest things.

I've felt well on LDN until this week, when I got 'hit' with a flare.

I feel I'm coming out of it but wonder if I should increase the LDN to 4.5,

stay at 3.0 mgs, or ??? Does Dr. B have an article about the doseages one

should take specifically for MS?

I have RR MS, (for 20 years)am not on any of the CRABs, won't do them, tried

Copaxone and got worse and lost weight, had new symptoms occur while on it

that I'd never had before, they stopped when I quit Copax).

I am a firm believer in LDN even thru this recent flareup - the stress level

has been at an all-time high in my home and I know this is what brings on

most of my flareups.

If anyone can email me about their experiences with having a flareup while

on LDN, if they stopped, changed doseages, etc, I'd appreciate the feedback.

I may not be able to read and reply to each email immediately as I am

fatigued and dealing with neuropathic pain.

Also live in hot Florida, but have been inside in A/C thru out this

exacerbation.

[Guest guest]

I fully agree with Bren: You should try to go up to 4.5mg. If after

an initial period of 4-7 days, you do not have particular problems

with this dosage, stay with it!

4.5mg gives more coverage.

Good Luck,

Massimo

> > I've been taking ldn, 3.0 mgs nightly for 2 months now. I

usually

> > have what I call 'mini flares' once or twice a year - which " slam-

> > dunk " me into stuck-in-bed-mode with that indescribable fatigue

that

> > makes it nearly impossible to do anything other than rest, lie in

> > bed, and rely on others to do the simplest things.

> > I've felt well on LDN until this week, when I got 'hit' with a

flare.

> > I feel I'm coming out of it but wonder if I should increase the

LDN

> > to 4.5, stay at 3.0 mgs, or ??? Does Dr. B have an article about

the

> > doseages one should take specifically for MS?

> > I have RR MS, (for 20 years)am not on any of the CRABs, won't do

> > them, tried Copaxone and got worse and lost weight, had new

symptoms

> > occur while on it that I'd never had before, they stopped when I

quit

> > Copax).

> > I am a firm believer in LDN even thru this recent flareup - the

> > stress level has been at an all-time high in my home and I know

this

> > is what brings on most of my flareups.

> > If anyone can email me about their experiences with having a

flareup

> > while on LDN, if they stopped, changed doseages, etc, I'd

appreciate

> > the feedback. I may not be able to read and reply to each email

> > immediately as I am fatigued and dealing with neuropathic pain.

> > Also live in hot Florida, but have been inside in A/C thru out

this

> > exacerbation.

> =============

>

> Try going up to 4.5mg. Dr. Bihari prefers this dosage if one can

tolerate it. Exacerbations of old symptoms can happen on LDN, these

are called pseudo exacerbations by Dr. Bihari. New symptoms never

experienced before would be known as MS progression so it's good that

it's old symptoms flaring and no new ones. And it's also good that

the flare is starting to subside fairly quickly, a good sign that LDN

is keeping the relapse short-lived.