Xolair Stats - Wonder if I'm having side effects

[Guest guest]

Since I'm not showing any improvement at all after 2+ months on Xolair

and, in fact, seem to be feeling worse in some ways (worse body aches,

numbness and tingling in extremities, sinusitis, colds, weight gain) I

looked up some statistics on Xolair. I found this from the Canada

Respiratory Journal in 2006:

.... in the evaluation by Bousquet et al ... , 38% of patients had a

response by 4 weeks and 64% by 16 weeks. Fewer than two-thirds of

patients who responded at 16 weeks had responded at four weeks; 87% had

shown a response by 12 weeks.

I do know that IgE can be accurately measured while on Xolair - that was

in an April 2007 journal of clinical allergy and immunology. Obviously

some people need more based on their IgE and probably other factors and

some need less. I'm really concerned about what this is doing to me.

It is completely unacceptable to expect anyone to blindly accept a drug

not working for many months. I certainly would not take an aspirin for

a headache now and be willing to wait six months for it to work. If it

doesn't work, there's something wrong and it needs to be investigated.

That isn't happening with Xolair. I am no little bit annoyed about it.

Genentech only puts out the party line - they're not answering some

serious questions.