Re: Re: Other Med Override Xolair? Questions!

[Guest guest]

I'm on the potassium bandwagon because of my topamax, which I take for

migraines, which are partially caused by my oral birth control, which I've

needed to take ever since I was on massive pred doses. Also take B-12 and a

multi-vitamin, and then there is the calcium supplement so that my bones don

t collapse as well... again from many years of evil candy.

I take a potassium tablet though, as I'm TECHNICALLY allergic to bananas and

orange juice. However, if I stayed away from EVERYTHING I'm TECHNICALLY

allergic to... I couldn't eat or drink anything but water and oatmeal.

All of this is of course done with the express written consent of major

league baseball! Right Addy? Go Red Sox!

-------Original Message-------

From: pyle456

Date: 10/13/07 13:26:35

Subject: [ ] Re: Other Med Override Xolair? Questions!

Simone, while I agree with you that Methotrexate might not be a good

choice for any one with a pulmonary disease, it may be the last

option to try for someone in instdsign's position who may have

already tried everything else.

All of us on this board are hard to treat patients just based on the

severity of our asthma alone, much less if one adds any other

factor. For example, because I have severe asthma I cannot take beta

blockers for my now severely high blood pressure (thank you,

prednisone), so I have to take another form of HBP medicine. Because

I have to take THAT, there are probably a slough of other meds I

won't be able to take for the NEXT condition I develop.

So, while I think we need to remind each other of drug side effects

and share our personal experiences, we have to remember that most of

us qualify for the sh*!-out-of-luck prize as far as concomintant

illnesses and drug effects are concerned.

Well, enough of that. I've gotta go rinse my sinuses, take my

Calcium/D supplement, eat a banana to get some postassium to counter

the effects of the HCT I take with my Diovan for my HBP, and pick up

my bone-building pills and advair inhaler at the pharmacy. (And y'all

please don't start on the advair warnings. I know about them and I'm

taking it 'cuz it's ragweed season and I don't care.)

Addy

Group co-owner

>

> Hi,

>

> I know living with an Auto Immune disease is a dreadful thing but

why

> would your doctor give you something that could potentially give you

> Pulmonary Fibrosis when its apparent you already have a lung

condition.

>

> Are you aware its also used along side Chemo drugs for cancer

patients

> and can have some pretty nasty side affects when used with

Penicillin

> also.

>

> Personally I would look at something else to take for your

Rheumatoid

> Arthritis, not even I would take Methotrexate for a thing it's a

very

> dangerous drug.

>

> Simone

>

> --- In , SD Designer <instdesgn1@>

wrote:

> >

> > I finally took my first dose of methotrexate on Wed. night for

> seronegative rheumatoid arthritis and had a very unpleasant

response.

> It was like a combination of a very bad allergy attack and the

> beginnings of an infection. My nose bled, my head was stopped up,

my

> nose, tongue, throat were " on fire " , I was dizzy (still am

somewhat), my

> nose ran clear mucous while I was asleep (all over when I woke up)

and I

> felt like I was completely dried up. My brain was absolutely

dulled out

> - couldn't remember how to get to certain places around town. This

> sounded a little like some of my reactions to antihistamines but

there

> was no antihistamine involved in several weeks.

> >

> > Is it possible for another drug to override the benefit of

Xolair?

> This reaction was something I would have had last fall (a year ago)

if I

> had spent the day doing heavy gardening - dirt, pollen, mold,

vegetation

> - all major nasty triggers, but, in fact, I had not been exposed to

any

> of the more severe triggers. Furthermore, I've been on Xolair since

> March and noticed this fall that I'm definitely better off than I

was a

> year ago at this time. Not free from allergy (still take Advair and

> Spiriva every day) but definitely more comfortable with fewer

symptoms.

> >

> > The only difference was the methotrexate which is known to cause

> infection in some people. Even my upper lip was partially swollen

and a

> little sore spot got much more sore. But, I didn't think that my

> experience was at all the typical experience w/methotrexate - in

fact,

> it seemed very allergic. So, I'm wondering if methotrexate simply

> removed the benefit of Xolair or if I really did have an allergic

> reaction to the other med because I haven't been on Xolair long

enough

> for complete protection (if that indeed ever happens)?

> >

> > The rheumy gave me this drug because of my very high test

results re

> inflammation plus definite arthritic history. She didn't know if

the

> high inflammation was from asthma (life long allergies) or

arthritis.

> That's another $64 question - how does one differentiate? I'm

hard to

> treat because of all my allergies and it looks like I'm going to

have to

> come up with my own treatment.

> >

> > Questions, questions, questions!

> >

> >

> > ---------------------------------

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> >