Re: Xolair stoppped working for me - Hives

[Guest guest]

Has your doctor considered adjusting your dose? I initially started on 150 per

month and it worked some of the time. We increased to 150/75 every two weeks

and it made a huge difference. Is that an option?

Lior <goquakers1978@...> wrote: I was one of

the few people who was approved to get Xolair injections

for chronic urticaria (hives). It worked for a year and half, giving

me my life back, but the hives and angiodema (swelling) returned in

full force. I had suffered with debilitating full body hives for over

a year until Xolair came along. After my third shot, I stopped hiving

until December of 2007 (I still had occasional red spots show up

during exercise). Then, out of thin air, I started to become

unresponsive to Xolair. I'm a 29 year old male and have dealt with

this autoimmune condition for three years. To have my one saving

grace taken away from me kind of leaves me hopeless; so I'm just venting.

---------------------------------

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[Guest guest]

I've actually been on 300 mg every two weeks (600 per month); so the

only thing I could do is go up to 375. Unfortunately, I don't think

that will work. Plus, I'm on this for non-IgE related urticaria.

Somehow, when I first started taking Xolair, it was downregulating the

IgE receptors to which autoantibodies binded and released histamine.

Now, that process has been stopped - probably because my body adapted.

I was

one of the few people who was approved to get Xolair injections

> for chronic urticaria (hives). It worked for a year and half, giving

> me my life back, but the hives and angiodema (swelling) returned in

> full force. I had suffered with debilitating full body hives for over

> a year until Xolair came along. After my third shot, I stopped hiving

> until December of 2007 (I still had occasional red spots show up

> during exercise). Then, out of thin air, I started to become

> unresponsive to Xolair. I'm a 29 year old male and have dealt with

> this autoimmune condition for three years. To have my one saving

> grace taken away from me kind of leaves me hopeless; so I'm just

venting.

>

>

>

>

>

>

> ---------------------------------

> Looking for last minute shopping deals? Find them fast with

Search.

>

>

[Guest guest]

Wow, Lior, what a shame. Will your allergist consider a trial of Xolair

at an increased dose?

Fran

>

> I was one of the few people who was approved to get Xolair injections

> for chronic urticaria (hives). It worked for a year and half, giving

> me my life back, but the hives and angiodema (swelling) returned in

> full force. I had suffered with debilitating full body hives for over

> a year until Xolair came along. After my third shot, I stopped hiving

> until December of 2007 (I still had occasional red spots show up

> during exercise). Then, out of thin air, I started to become

> unresponsive to Xolair. I'm a 29 year old male and have dealt with

> this autoimmune condition for three years. To have my one saving

> grace taken away from me kind of leaves me hopeless; so I'm just

venting.

>

[Guest guest]

I agree about trying an increased dose.

> >

> > I was one of the few people who was approved to get Xolair

injections

> > for chronic urticaria (hives). It worked for a year and half,

giving

> > me my life back, but the hives and angiodema (swelling) returned

in

> > full force. I had suffered with debilitating full body hives for

over

> > a year until Xolair came along. After my third shot, I stopped

hiving

> > until December of 2007 (I still had occasional red spots show up

> > during exercise). Then, out of thin air, I started to become

> > unresponsive to Xolair. I'm a 29 year old male and have dealt

with

> > this autoimmune condition for three years. To have my one saving

> > grace taken away from me kind of leaves me hopeless; so I'm just

> venting.

> >

>

[Guest guest]

Hi:

What does your doctor say, why did it stop working?

Kathy

pyle456 <coachmac@...> wrote:

I agree about trying an increased dose.

> >

> > I was one of the few people who was approved to get Xolair

injections

> > for chronic urticaria (hives). It worked for a year and half,

giving

> > me my life back, but the hives and angiodema (swelling) returned

in

> > full force. I had suffered with debilitating full body hives for

over

> > a year until Xolair came along. After my third shot, I stopped

hiving

> > until December of 2007 (I still had occasional red spots show up

> > during exercise). Then, out of thin air, I started to become

> > unresponsive to Xolair. I'm a 29 year old male and have dealt

with

> > this autoimmune condition for three years. To have my one saving

> > grace taken away from me kind of leaves me hopeless; so I'm just

> venting.

> >

>

---------------------------------

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[Guest guest]

He has no idea. Autoimmune and other chronic conditions seem to be

able to adapt and make previously effective medication totally

useless. I went up to 450 mg. today, but I am not holding my breath.

I might have to try IVIG next or Cellcept (immunosuppressant).

> > >

> > > I was one of the few people who was approved to get Xolair

> injections

> > > for chronic urticaria (hives). It worked for a year and half,

> giving

> > > me my life back, but the hives and angiodema (swelling) returned

> in

> > > full force. I had suffered with debilitating full body hives for

> over

> > > a year until Xolair came along. After my third shot, I stopped

> hiving

> > > until December of 2007 (I still had occasional red spots show up

> > > during exercise). Then, out of thin air, I started to become

> > > unresponsive to Xolair. I'm a 29 year old male and have dealt

> with

> > > this autoimmune condition for three years. To have my one saving

> > > grace taken away from me kind of leaves me hopeless; so I'm just

> > venting.

> > >

> >

>

>

>

>

>

>

> ---------------------------------

> Looking for last minute shopping deals? Find them fast with

Search.

>

>