Re: inverse associations between allergic diseases and malignancies?

[Guest guest]

Sorry - I didn't check the messages before I sent off my posting from

what was probably the same study, just a different web site! Guess

those of us with severe allergies are always looking for some sort of

silver lining!

--- In , " Mark Headley " <mjheadley@...>

wrote:

>

> (Moderator's note: Mark has kindly provided the website for an

interesting abstract suggesting that IgE may act in tumor

surveillance and could possibly be manipulated for tumor control.

The abstract makes it clear that it's early days, but VERY

INTERESTING.)

>

>

>

> http://www3.interscience.wiley.com/journal/121356813/abstract?

CRETRY=1 & SRETRY=0

>

> Allergy. 2008 Jul 29

>

> AllergoOncology: the role of IgE-mediated allergy in cancer.

>

> Jensen-Jarolim E, Achatz G, MC, Karagiannis S, Legrand F,

Capron M, Penichet ML, Rodríguez JA, Siccardi AG, Vangelista L,

Riemer AB, Gould H.

>

> Department of Pathophysiology, Center of Physiology,

Pathophysiology and Immunology, Medical University Vienna, Austria.

>

> Epidemiological studies have suggested inverse associations between

allergic diseases and malignancies.

>

> IgE antibodies specific to overexpressed tumor antigens

>

> IgE nonspecifically attached to tumor cells proved to be a powerful

adjuvant establishing tumor-specific immune memory.

>

>