Re: benefits after worsening from 1st 3 injections? other than w/ asthma/anaphalaxis

March 15, 2008

I believe it was during or close to the first three months of Xolair

that I developed a horrible cold, sinusitis, bronchitis, that lasted

quite a while and seemed to have an increase in arthritis. I

certainly did not feel good (although I don't think I reacted to the

shots) much of the time even though my pft showed slight

improvement. (What does a pft know? <grin>)

I still get the colds with sinusitis and bronchitis 3 or 4 times a

year. The good news is that my pulmo takes it seriously and jumps in

to treat me immediately to avoid any more damage to my lungs. But, I

had the same rate BEFORE Xolair.

Here's sort've my improvement and lack of improvement in various

areas:

Asthma - overall, I'm definitely better and lung function tests show

it. I do still have to use Advair & Spiriva but am getting easier

breathing than pre-Xolair and that is especially significant in

situations where I would normally have a major attack like in dirty

dusty situations or gardening.

Sinuses - these were " killers " for me and often misdiagnosed as daily

headaches or migraines. (I'd like to find the neurologist who told

me that and shove the reports in his sinuses) They've improved a

great deal and I only take Sudafed about once every 10 days or so

whereas before it was several times every day. Again, though, just

like the asthma it was very slow and gradual change and w/sinuses

took 9 months to show improvement.

Arthritis - I don't know what's causing it but I'd say I'm a tad bit

worse. Could be increasing age or other factors - I don't know.

Maybe it was going to happen anyway.

Chronic Diarrhea - There have been periods of time when I was

significantly better but it's not continuous. Xolair might have

helped but I really don't know. March 23rd will be my " One Year

Anniversary " of using Xolair. Hope springs eternal and I'm hoping

for more improvement as I go on.

Hope good things will come your way.

--- In , " markmehers " <mjheadley@...>

wrote:

>

> I just joined. lottawood, I have experence the same adverse

effects

> as you with my first 3 injections, and not only are they lingering,

> I'm not sure they've peaked.

>

> Also, while I have a history of mild asthma with sinusitis,

> susceptability to acute, albeit transient, attacks when exposed to

> many fragrances, and a propensity to anaphylaxis, I've been

> undergoing Xolair administration in the hope it will help with

other

> severe chronic " mediator symptoms " from systemic mast cell

disease:

> especially excruciating abdominal pain linked to excessive

histamine

> and perhaps other " mediators " ; also intense pain from related

> interstitial cystitis/prostatitis.

>

> So I feel that I'm at a crossroads.

>

> Has anyone experienced dramatic improvement/resolution with

> impairments other than asthma and incidence of anaphylaxis/acute

> attacks AFTER weathering a worsening of symptoms and other adverse

> effects the first 3 months?

>

> Thanks

>

March 16, 2008

i just wanted to commment here please....

my son has been takin xolair shots for his severe asthma/sinus as

well... my son hasnt had any adverse effects...thats why they give it

to him in his drs office so that way if there is problems they can

treat him there...

if u need any other assistance or questions answered i will be glad

to help out...

my son has had severe asthma since birth.. he is 15 now.. still

dealing.. so i have been very blessed for this xolair.. its been a

miracle for him...

i hope the xolair is helpin many others here...

many blessings to everyone here..

god bless