Re: Re: Allergies, Asthma, Arthritis, Xolair & Plaquenil

[Guest guest]

why does xolair raise your IgE level? I'm working on getting it approved for my

daughter for atopic dermatitis. Her level is already almost 6,000. I don't

want ot to go higher. Am I missing something here. thanks for any info. jean

---- billybaroo1958 <cajjz109@...> wrote:

> Ok, first the Plaquenil shouldn't really effect your allergies. It is a

T-cell modulater and if

> anything might improve some of your inflammatory symptoms associated with your

> allergies or asthma. The raise in IgE is not so unusual while being on Xolair.

How long have

> you been on it? While your IgE off Xolair was moderately high (mine was 345

before), it

> doesn't necessarily correlate to allergic reactions. Did you have certain

antigens that

> promoted your asthma episodes? The reason why I ask is because if you still

needed all

> the other meds along with Xolair to keep your asthma somewhat controlled, then

it wasn't

> controlled entirely as a result of anti-IgE. So, your flare-up now might be

driven for other

> reasons than IgE. Anyway, the arthritis might be playing a role in

exacerbations.

>

>

>

> >

> > Ok, I'm back at it again with arthritis meds along with my Xolair and

> > associated asthma meds - Advair (500/50), Spiriva, Albuterol.

> >

> > I was diagnosed w/Serro negative rheumatoid arthritis almost a year ago

> > and after having a bad experience with methotrexate (which is known to

> > cause lung disease although others on this board have gotten along ok

> > w/it) I was afraid to take Plaquenil. The stiffness and pain finally

> > drove me to start it 4 nights ago at just 50 mgs once in the evening.

> > It's normally prescribed at 200 mgs twice a day. I'm nervous because I

> > have a long history of unpleasant drug side effects.

> >

> > While consulting w/my pulmo recently I thought she said something about

> > the Plaquenil helping (as in making better) one of my allergic

> > complaints so I assume that the anti-inflammatory properties of

> > Plaquenil must reduce the allergic inflammation also?

> >

> > Again, has anyone tried Plaquenil who has severe allergies (My IgE was

> > 409 before Xolair and on Xolair over 1200)???? I've been having a

> > rather bad time for several weeks - can hear myself wheezing softly

> > (actually thought it was the cat purring until I held my breath and

> > noticed the cat " stopped " purring!!!) and even my hubby can hear it.

> > So, the current treatments are not really enough to keep the allergies

> > truly under control right now.

> >

> > I guess that theoretically the dose is so low on Plaquenil that it

> > shouldn't have any effect although I think it is causing nightmarish

> > disturbing dreams. I thought I was a bit more irritable too plus there

> > was decreasing nausea the first 3 nights. On the other hand, I'm

> > hoping I'll be able to work up gradually to the normal dose. It would

> > be good to control two different diseases (although several docs have

> > told me that arthritis, allergies, and asthma are all related) at the

> > same time.

> >

> > It's doubtful that any influence on Xolair or vice versa is known since

> > Xolair is so new and it works on different systems (I assume) and in a

> > completely different way.

> >

> > Plaquenil comments, anyone?

> > Thx

> >

>

>

>