Re: How asthma medicines developed through the ages

[Guest guest]

I remember taking a pill called Brethine, I think - sometime in the late

70's through the early 80 " s. Made me a nervous wreck! I think it was

basically some form of speed.

2009/3/20 uca79iii <uca79iii@...>

> http://www.rpsgb.org.uk/pdfs/mussheetasthma.pdf

>

> We have come a lonnnnnnnnnnnnng way!

>

>

>

--

From the abundance of the heart the mouth speaks. - Prince

[Guest guest]

I took Brethine (terbutaline) to control preterm labor with 3 of my 5

pregnancies. It was like drinking way too many cups of caffeine. Imagine

having to do 3 months of bedrest while on it! I took it both in oral form

and a subcutaneous pump. My hands would shake so much I couldn't do crafts

or hold a book. But my asthma was not a bother. LOL!!

I have those same shakes today due to my Uniphyll (theophylline) and Advair,

and less sleep than normal this week. Throw in ADHD and I think my family

will want to sedate me later today. I am very bouncy today, but at least I

can get up and move about. I am trying to stop and do some yoga or

meditation today to calm down a bit every 30-60 minutes. It does help.

From: [mailto: ] On

Behalf Of Stesia

Sent: Friday, March 20, 2009 10:51 AM

Subject: Re: [ ] How asthma medicines developed through the ages

I remember taking a pill called Brethine, I think - sometime in the late

70's through the early 80 " s. Made me a nervous wreck! I think it was

basically some form of speed.

2009/3/20 uca79iii <uca79iii@... <mailto:uca79iii%40gmail.com> >

> http://www.rpsgb.org.uk/pdfs/mussheetasthma.pdf

>

> We have come a lonnnnnnnnnnnnng way!

>

>

>

--

From the abundance of the heart the mouth speaks. - Prince

[Guest guest]

>

> I remember taking a pill called Brethine, I think - sometime in the late

> 70's through the early 80 " s. Made me a nervous wreck! I think it was

> basically some form of speed.

>

Here is what health says about Brethine:

http://health./asthma-medications/terbutaline-oral/healthwise--d00752n1\

..html

I took it at one time too ALONG with prednisone. Can you imagine they would give

a hyperactive person BOTH those drugs at the same time?

I was not only bouncing off the walls, I was going through them LOL!

Doug

[Guest guest]

Brethine is terbutaline. Now primarily used as a tocolytic agent (halt early

labor), is very structurally similar to albuterol (Ventolin/Proventil).

I was on theophylline as a kid, vomited all the time, no doubt I was toxic!

>

> I remember taking a pill called Brethine, I think - sometime in the late

> 70's through the early 80 " s. Made me a nervous wreck! I think it was

> basically some form of speed.

>

> 2009/3/20 uca79iii <uca79iii@...>

>

> > http://www.rpsgb.org.uk/pdfs/mussheetasthma.pdf

> >

> > We have come a lonnnnnnnnnnnnng way!

> >

> >

> >

>

>

>

> --

> From the abundance of the heart the mouth speaks. - Prince

>

>

>

[Guest guest]

I never took the tablet, but I did use the terbutaline inhaler and it was

nothing short of nasty!  It never really helped me because it made me sick at my

stomach!

From: uca79iii <uca79iii@...>

Subject: [ ] Re: How asthma medicines developed through the ages

Date: Friday, March 20, 2009, 11:04 AM

>

> I remember taking a pill called Brethine, I think - sometime in the late

> 70's through the early 80 " s. Made me a nervous wreck! I think it was

> basically some form of speed.

>

Here is what health says about Brethine:

http://health. / asthma-medicatio ns/terbutaline- oral/healthwise-

-d00752n1. html

I took it at one time too ALONG with prednisone. Can you imagine they would give

a hyperactive person BOTH those drugs at the same time?

I was not only bouncing off the walls, I was going through them LOL!

Doug

[Guest guest]

Brethine and prednisone - yep, that was my cocktail for sure! And then they

added theophylline (after which I think I phased out the Brethine). Man!

Until they could figure out what dose to give me, theophylline made me so

sick I wanted to commit suicide. Nasty! Nasty! Nasty!

And did anyone take Intal when it was a capsule that you punctured and then

inhaled the powder? That one got me hauled into the principal's office!

Someone said I was dealing drugs! I was in Jr. High - around 1976, 1977.

On Fri, Mar 20, 2009 at 10:04 AM, uca79iii <uca79iii@...> wrote:

>

> >

> > I remember taking a pill called Brethine, I think - sometime in the late

> > 70's through the early 80 " s. Made me a nervous wreck! I think it was

> > basically some form of speed.

> >

>

> Here is what health says about Brethine:

>

>

>

http://health./asthma-medications/terbutaline-oral/healthwise--d00752n1\

..html

>

> I took it at one time too ALONG with prednisone. Can you imagine they would

> give a hyperactive person BOTH those drugs at the same time?

> I was not only bouncing off the walls, I was going through them LOL!

>

> Doug

>

>

>

--

From the abundance of the heart the mouth speaks. - Prince

[Guest guest]

And another childhood horror story, one that continues today... By the time

I was in about 5th-6th grade, I had a Dowager's hump from all the steroids

(I was diagnosed with asthma at about 6months of age). I can remember the

gym teacher making us do somersaults and I would beg and plead with her to

get out of it. I always hit that hump as I rolled and it hurt. I also have

very thin hair and have almost no hair on my body (except my head, but it is

thin and fine). Well at least I don't need to shave but maybe once a year!

On Fri, Mar 20, 2009 at 11:03 PM, Stesia <annastesia926@...>wrote:

> Brethine and prednisone - yep, that was my cocktail for sure! And then

> they added theophylline (after which I think I phased out the Brethine).

> Man! Until they could figure out what dose to give me, theophylline made me

> so sick I wanted to commit suicide. Nasty! Nasty! Nasty!

>

> And did anyone take Intal when it was a capsule that you punctured and then

> inhaled the powder? That one got me hauled into the principal's office!

> Someone said I was dealing drugs! I was in Jr. High - around 1976, 1977.

>

>

> On Fri, Mar 20, 2009 at 10:04 AM, uca79iii <uca79iii@...> wrote:

>

>>

>> >

>> > I remember taking a pill called Brethine, I think - sometime in the late

>> > 70's through the early 80 " s. Made me a nervous wreck! I think it was

>> > basically some form of speed.

>> >

>>

>> Here is what health says about Brethine:

>>

>>

>>

http://health./asthma-medications/terbutaline-oral/healthwise--d00752n1\

..html

>>

>> I took it at one time too ALONG with prednisone. Can you imagine they

>> would give a hyperactive person BOTH those drugs at the same time?

>> I was not only bouncing off the walls, I was going through them LOL!

>>

>> Doug

>>

>>

>>

>

>

>

> --

> From the abundance of the heart the mouth speaks. - Prince

>

--

From the abundance of the heart the mouth speaks. - Prince

[Guest guest]

I took terbutaline for preterm labor and was also on the terb pump, all

before I was diagnosed with asthma.

My mom took both terb and theophylline for her asthma and was horribly

wired, her doctor told her it was chemically similar to caffeine and that her

body

would eventually tolerate it better. I remember shaking; trying to write or

do cross stitch when I was on bed rest was sporting. FYI

Debbie

**************A Good Credit Score is 700 or Above. See yours in just 2 easy

steps!

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F%2Fwww.freecreditreport.com%2Fpm%2Fdefault.aspx%3Fsc%3D668072%26hmpgID

%3D62%26bcd%3DMarchfooterNO62)

[Guest guest]

I never had that drug but theophyline makes me nuts

 

one medication as a kid. asbron (not sure of spelling), it was a green liquid

med...turned out when I took it, I was getting sicker by the minute. When I was

5....that was my first experience of almost losing my life. Been 3 other times

since then.

From: uca79iii <uca79iii@...>

Subject: [ ] Re: How asthma medicines developed through the ages

Date: Friday, March 20, 2009, 12:04 PM

>

> I remember taking a pill called Brethine, I think - sometime in the late

> 70's through the early 80 " s. Made me a nervous wreck! I think it was

> basically some form of speed.

>

Here is what health says about Brethine:

http://health. / asthma-medicatio ns/terbutaline- oral/healthwise-

-d00752n1. html

I took it at one time too ALONG with prednisone. Can you imagine they would give

a hyperactive person BOTH those drugs at the same time?

I was not only bouncing off the walls, I was going through them LOL!

Doug

[Guest guest]

>

> And another childhood horror story, one that continues today... By the time

> I was in about 5th-6th grade, I had a Dowager's hump from all the steroids

> (I was diagnosed with asthma at about 6months of age). I can remember the

> gym teacher making us do somersaults and I would beg and plead with her to

> get out of it. I always hit that hump as I rolled and it hurt. I also have

> very thin hair and have almost no hair on my body (except my head, but it is

> thin and fine). Well at least I don't need to shave but maybe once a year!

>

I shared with the group a few years back about my Jr. High gym class horror

story in 1969. The coach gave me two swats for not running with the other boys.

All I asked the idiot to do was let me call my mom to bring me my primatine

inhaler.

ahhhhh school days!

[Guest guest]

I took both terbutaline and theophylline when I was in my teens and without any

blood levels check on the theo. I weighed less than 100 pounds. I finally took

MYSELF off them because I could barely function from all the side effects. I

have not taken either since, and I categorically refuse to take theophylline.

Addy

Group co-owner

S.A.B.

>

> I took terbutaline for preterm labor and was also on the terb pump, all

> before I was diagnosed with asthma.

> My mom took both terb and theophylline for her asthma and was horribly

> wired, her doctor told her it was chemically similar to caffeine and that her

body

> would eventually tolerate it better. I remember shaking; trying to write or

> do cross stitch when I was on bed rest was sporting. FYI

>

> Debbie

> **************A Good Credit Score is 700 or Above. See yours in just 2 easy

> steps!

>

(http://pr.atwola.com/promoclk/100126575x1220863691x1201421954/aol?redir=http:%2\

F%2Fwww.freecreditreport.com%2Fpm%2Fdefault.aspx%3Fsc%3D668072%26hmpgID

> %3D62%26bcd%3DMarchfooterNO62)

>

>

>

[Guest guest]

Does anyone else take Tilade? It tastes gross. I had to use it without its

spacer once, and it turned my tongue yellow!

Good link, Doug. It's interesting to see that some of the herbal treatments have

been around for so long. I know people who use those exclusively and with

success. My lungs are too far gone at this point. I do miss my Yogi tea with

real ephedra in it. That stuff was amazing. Come to think of it, my breathing

went downhill hard right after the ephedra ban. Suppose I can sue? *teehee*.

Maybe if we all lived in a world as non-toxic as it was hundreds of years ago,

all we'd need was an herb. Or if we'd have asthma at all.

>

> I never took the tablet, but I did use the terbutaline inhaler and it was

nothing short of nasty!  It never really helped me because it made me sick at my

stomach!

>

>

[Guest guest]

Addy, I never had a theophylline level performed either. I only learned about

such things when I was in pharmacy school. It quite explained my vomiting

episodes. Thankfully I didn't stay on theophylline too long. Fortunately

theophylline has fallen to the wayside, and if used now is in an extended

release format at usually substantially lower doses (now for antiinflammatory

effect versus bronchodilation), so all patients with asthma are spared the pain

we suffered as kids.

> >

> > I took terbutaline for preterm labor and was also on the terb pump, all

> > before I was diagnosed with asthma.

> > My mom took both terb and theophylline for her asthma and was horribly

> > wired, her doctor told her it was chemically similar to caffeine and that

her body

> > would eventually tolerate it better. I remember shaking; trying to write

or

> > do cross stitch when I was on bed rest was sporting. FYI

> >

> > Debbie

> > **************A Good Credit Score is 700 or Above. See yours in just 2 easy

> > steps!

> >

(http://pr.atwola.com/promoclk/100126575x1220863691x1201421954/aol?redir=http:%2\

F%2Fwww.freecreditreport.com%2Fpm%2Fdefault.aspx%3Fsc%3D668072%26hmpgID

> > %3D62%26bcd%3DMarchfooterNO62)

> >

> >

> >

[Guest guest]

my son was on theophylline when he was 5 for a very short time. it made him

so hyper he would run from room to room and jump all over the furniture. he

looked like a mad man. I took him off and he wa fine. I hated that med.

jean

On Mon, Mar 23, 2009 at 7:59 AM, fpa9 <fpa9@...> wrote:

> Addy, I never had a theophylline level performed either. I only learned

> about such things when I was in pharmacy school. It quite explained my

> vomiting episodes. Thankfully I didn't stay on theophylline too long.

> Fortunately theophylline has fallen to the wayside, and if used now is in an

> extended release format at usually substantially lower doses (now for

> antiinflammatory effect versus bronchodilation), so all patients with asthma

> are spared the pain we suffered as kids.

>

>

> > >

> > > I took terbutaline for preterm labor and was also on the terb pump, all

>

> > > before I was diagnosed with asthma.

> > > My mom took both terb and theophylline for her asthma and was horribly

> > > wired, her doctor told her it was chemically similar to caffeine and

> that her body

> > > would eventually tolerate it better. I remember shaking; trying to

> write or

> > > do cross stitch when I was on bed rest was sporting. FYI

> > >

> > > Debbie

> > > **************A Good Credit Score is 700 or Above. See yours in just 2

> easy

> > > steps!

> > > (

>

http://pr.atwola.com/promoclk/100126575x1220863691x1201421954/aol?redir=http:%2F\

%2Fwww.freecreditreport.com%2Fpm%2Fdefault.aspx%3Fsc%3D668072%26hmpgID

> > > %3D62%26bcd%3DMarchfooterNO62)

> > >

> > >

> > >

[Guest guest]

>

> my son was on theophylline when he was 5 for a very short time. it made him

> so hyper he would run from room to room and jump all over the furniture. he

> looked like a mad man. I took him off and he wa fine. I hated that med.

> jean

>

>

I took a yellow liquid medicine that tasted like licorice. It was called Tedral.

It was a mixture of Theophylline/Ephedrine and Phenobarbital. ALL I remember is

that it opened me up and gave me relief.

[Guest guest]

Major problem with that combination are three things:

1- Cardiovascular risks with the non-selective drug, ephedra

2- Eventual tolerance/tachyphylaxis with ephedra

3- Not treating underlying inflammation, which progresses to make asthma much

worse later in life, leading to irreversible disease. Inhaled steroids have

demonstrated to work on the inflammation portion.

> >

> > my son was on theophylline when he was 5 for a very short time. it made him

> > so hyper he would run from room to room and jump all over the furniture. he

> > looked like a mad man. I took him off and he wa fine. I hated that med.

> > jean

> >

> >

>

>

> I took a yellow liquid medicine that tasted like licorice. It was called

Tedral. It was a mixture of Theophylline/Ephedrine and Phenobarbital. ALL I

remember is that it opened me up and gave me relief.

>

[Guest guest]

>

> Addy, I never had a theophylline level performed either. I only learned about

such things when I was in pharmacy school. It quite explained my vomiting

episodes. Thankfully I didn't stay on theophylline too long. Fortunately

theophylline has fallen to the wayside, and if used now is in an extended

release format at usually substantially lower doses (now for antiinflammatory

effect versus bronchodilation), so all patients with asthma are spared the pain

we suffered as kids.

I take theophylline. I've been on it since shortly before I started Xolair. {I

think that's two years. My sense of time isn't working these days.] Since I

can't take anything with even a hint of steroid in it, my pharmacy has to use

their time machine to fill my presciptions.

[Guest guest]

Why can not use an inhaled steroid?

> >

> > Addy, I never had a theophylline level performed either. I only learned

about such things when I was in pharmacy school. It quite explained my vomiting

episodes. Thankfully I didn't stay on theophylline too long. Fortunately

theophylline has fallen to the wayside, and if used now is in an extended

release format at usually substantially lower doses (now for antiinflammatory

effect versus bronchodilation), so all patients with asthma are spared the pain

we suffered as kids.

>

>

> I take theophylline. I've been on it since shortly before I started Xolair. {I

think that's two years. My sense of time isn't working these days.] Since I

can't take anything with even a hint of steroid in it, my pharmacy has to use

their time machine to fill my presciptions.

>

>

>

[Guest guest]

, I am on Uniphyll, a long acting theophylline in addition to a

small dose of Flovent. My doctors are tapering me off the Flovent versus the

Uniphyll as I am having pressure issues in my left eye. He said some are

just much more sensitive to the steroids than others. So far the Uniphyll

and Xoliar combination have worked well for me.

I had been on oral pred and 500/50 Advair when I started Xolair 2.5 yrs ago.

Inflammation has always been my biggest issue with the allergic asthma.

From: [mailto: ] On

Behalf Of

Sent: Tuesday, March 24, 2009 10:20 AM

Subject: [ ] Re: How asthma medicines developed through the ages

>

> Addy, I never had a theophylline level performed either. I only learned

about such things when I was in pharmacy school. It quite explained my

vomiting episodes. Thankfully I didn't stay on theophylline too long.

Fortunately theophylline has fallen to the wayside, and if used now is in an

extended release format at usually substantially lower doses (now for

antiinflammatory effect versus bronchodilation), so all patients with asthma

are spared the pain we suffered as kids.

I take theophylline. I've been on it since shortly before I started Xolair.

{I think that's two years. My sense of time isn't working these days.] Since

I can't take anything with even a hint of steroid in it, my pharmacy has to

use their time machine to fill my presciptions.

[Guest guest]

My sister took Tedral in the form of a tablet and it took about 30 minutes to

begin to get any relief.  I had one bad attack as a child and Mom gave me the

Tedral.  It worked, but I remember feeling like I wanted to jump out of my skin!

From: uca79iii <uca79iii@...>

Subject: [ ] Re: How asthma medicines developed through the ages

Date: Tuesday, March 24, 2009, 7:45 AM

>

> my son was on theophylline when he was 5 for a very short time. it made him

> so hyper he would run from room to room and jump all over the furniture. he

> looked like a mad man. I took him off and he wa fine. I hated that med.

> jean

>

>

I took a yellow liquid medicine that tasted like licorice. It was called Tedral.

It was a mixture of Theophylline/ Ephedrine and Phenobarbital. ALL I remember is

that it opened me up and gave me relief.

[Guest guest]

I'm on Theophylin and wish I had a small amount of the energy you describe. 

 Mike McBride

Don't cry because it's over, laugh because it happened. Dr. Seuss

________________________________

From: Adah Voigt <asthmatic50@...>

Sent: Tuesday, March 24, 2009 3:23:03 PM

Subject: Re: [ ] Re: How asthma medicines developed through the ages

My sister took Tedral in the form of a tablet and it took about 30 minutes to

begin to get any relief.  I had one bad attack as a child and Mom gave me the

Tedral.  It worked, but I remember feeling like I wanted to jump out of my skin!

From: uca79iii <uca79iiigmail (DOT) com>

Subject: [ ] Re: How asthma medicines developed through the ages

Date: Tuesday, March 24, 2009, 7:45 AM

>

> my son was on theophylline when he was 5 for a very short time. it made him

> so hyper he would run from room to room and jump all over the furniture. he

> looked like a mad man. I took him off and he wa fine. I hated that med.

> jean

>

>

I took a yellow liquid medicine that tasted like licorice. It was called Tedral.

It was a mixture of Theophylline/ Ephedrine and Phenobarbital. ALL I remember is

that it opened me up and gave me relief.

[Guest guest]

>

> Why can not use an inhaled steroid?

>

It makes me psychotic. I don't mean mood swings either. I mean

homicidal/suicidal psychotic.

My old doctor tried to put me on Advair. Said it would stay in my lungs and not

be systemic. It just took two days longer to make me crazy. My new doctor said

the same thing about a nasal spray. " Only a trace. You'll never notice. Even the

most sensitive people can use this. "

My husband took it away from me after four days. I've even reacted to a topical.

So no steroids for me! At least I don't have to worry about all the nasty side

effects I hear about from long time users in this group. My lungs may be tight

sometimes, but at least I'm not disintegrating!

[Guest guest]

Very interesting. I have done a lot of specialized clinical work and research

with asthma pharmacology, focusing on inhaled corticosteroids, but I have never

witnessed this. I have, however read about it in the literature. how do you

react to oral/iv steroids? the same? are you able to go on a 'burst' of oral

steroids if you have an exacerbation?

> >

> > Why can not use an inhaled steroid?

> >

>

>

> It makes me psychotic. I don't mean mood swings either. I mean

homicidal/suicidal psychotic.

>

> My old doctor tried to put me on Advair. Said it would stay in my lungs and

not be systemic. It just took two days longer to make me crazy. My new doctor

said the same thing about a nasal spray. " Only a trace. You'll never notice.

Even the most sensitive people can use this. "

> My husband took it away from me after four days. I've even reacted to a

topical.

>

> So no steroids for me! At least I don't have to worry about all the nasty side

effects I hear about from long time users in this group. My lungs may be tight

sometimes, but at least I'm not disintegrating!

>

[Guest guest]

Wow, did they ever have to put you on an antipsychotic after being on

steroids?

_____

From: [mailto: ] On

Behalf Of

Sent: Wednesday, March 25, 2009 10:25 AM

Subject: [ ] Re: How asthma medicines developed through the ages

>

> Why can not use an inhaled steroid?

>

It makes me psychotic. I don't mean mood swings either. I mean

homicidal/suicidal psychotic.

My old doctor tried to put me on Advair. Said it would stay in my lungs and

not be systemic. It just took two days longer to make me crazy. My new

doctor said the same thing about a nasal spray. " Only a trace. You'll never

notice. Even the most sensitive people can use this. "

My husband took it away from me after four days. I've even reacted to a

topical.

So no steroids for me! At least I don't have to worry about all the nasty

side effects I hear about from long time users in this group. My lungs may

be tight sometimes, but at least I'm not disintegrating!

[Guest guest]

>

> Wow, did they ever have to put you on an antipsychotic after being on

> steroids?

>

>

No, when I stop the steroids the problems go away pretty quickly. It has been

suggested that I take an antipsychotic so that I can take steroids. But that

is a game I refuse to play!