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Xolair and Heart Disease

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Hi all,

I was diagnosed last week with Congestive Heart Failure. I've been looking at

Xolair and have not seen this as a possible side effefct. My first Xolair shot

was 1/3/09 so I wondered if there was a relation. Has anyone heard if there is

a connection? If not, does heart disease contraindicate Xolair?

Thanks

Mike

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Mike,

Sorry to hear about your diagnosis. I have never heard of that as a side effect

of xolair. But, with any drug that has been out for only a few years, they can

find things out later on. You should ask your doctor whether or not it is still

safe to take xolair with congestive heart failure. They would be the best to

tell you those things.

From: Mike <mike.dmcbride@...>

Subject: [ ] Xolair and Heart Disease

Date: Sunday, April 26, 2009, 10:27 AM

Hi all,

I was diagnosed last week with Congestive Heart Failure. I've been looking at

Xolair and have not seen this as a possible side effefct. My first Xolair shot

was 1/3/09 so I wondered if there was a relation. Has anyone heard if there is

a connection? If not, does heart disease contraindicate Xolair?

Thanks

Mike

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I recall reading that xolair can alter Nitrous Oxide blood levels and I believe

this has something to do with cardiovasular functioning but I am not a doctor.

Straining to breath can contribute to congestive heart failure.  I am very very

sorry to hear this. 

LMA

________________________________

From: Mike <mike.dmcbride@...>

Sent: Sunday, April 26, 2009 10:27:49 AM

Subject: [ ] Xolair and Heart Disease

Hi all,

I was diagnosed last week with Congestive Heart Failure. I've been looking at

Xolair and have not seen this as a possible side effefct. My first Xolair shot

was 1/3/09 so I wondered if there was a relation. Has anyone heard if there is a

connection? If not, does heart disease contraindicate Xolair?

Thanks

Mike

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Thanks Harold,

My hospital is good enough to forward the test results both to the doctor who

ordered the test (my internist) as well as to any I ask for, including my

pulmonologist.  I'll see the pulmo folks on 5/7.

 Mike McBride

" Failure is not fatal unless you quit; getting knocked down is not embarrassing

unless you allow it to keep you down. " Ashcroft

________________________________

From: Harold Pineo <haroldbrenda@...>

Sent: Sunday, April 26, 2009 10:25:43 AM

Subject: Re: [ ] Xolair and Heart Disease

Mike,

Sorry to hear about your diagnosis. I have never heard of that as a side effect

of xolair. But, with any drug that has been out for only a few years, they can

find things out later on. You should ask your doctor whether or not it is still

safe to take xolair with congestive heart failure. They would be the best to

tell you those things.

From: Mike <mike.dmcbride>

Subject: [ ] Xolair and Heart Disease

Date: Sunday, April 26, 2009, 10:27 AM

Hi all,

I was diagnosed last week with Congestive Heart Failure. I've been looking at

Xolair and have not seen this as a possible side effefct. My first Xolair shot

was 1/3/09 so I wondered if there was a relation. Has anyone heard if there is a

connection? If not, does heart disease contraindicate Xolair?

Thanks

Mike

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Mike,

I started Xolair in October, 2003. June, 2007, I was diagnosed with very high

blood pressure, which is well controlled with a relatively small dosage of

diovan. My doc ran me through lots of tests, including a nuclear stress test.

Nothing interesting came up. Both my GP and my pulmo agree that the high bp is

another generous gift of the years of prednisone that I've taken.

We're all different. I haven't heard of Xolair causing or being contraindicated

in heart disease. You might be special, you might be the first one, who knows.

One important thing to remember is that asthma attacks put strain on the heart

by forcing the blood to work harder to move decreased levels of oxygen around

our bodies. the way I look at it, I have to do whatever I can to protect my

lungs in order to maintain my heart health.

I'm sorry to hear about your diagnosis. If I were you, I would ask your Xolair

doc to contact National Jewish. They did a lot of the testing with Xolair and

they get lots of patients with multiple difficult diagnoses. If your doc

consults with National Jewish, you should get some really good info.

Let us know, and take good care of yourself.

Addy

Group co-owner

>

> Hi all,

>

> I was diagnosed last week with Congestive Heart Failure. I've been looking at

Xolair and have not seen this as a possible side effefct. My first Xolair shot

was 1/3/09 so I wondered if there was a relation. Has anyone heard if there is

a connection? If not, does heart disease contraindicate Xolair?

>

> Thanks

> Mike

>

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Mike,

I started Xolair injections in July 2008. In Nov. 2008 I was diagnosed with an

atrial valve flow murmur & a pericardial effusion (fancy name for fluid around

the heart). After many tests & doctor visits, my cardiologist believes the fluid

was caused by too high of a level of synthroid (taken for hypothyroidism)and the

murmur is a probably a result of years of high blood pressure. The last echo

showed that the fluid is now gone. At no point in time did he or any of my other

doctors suggest that I quit Xolair.

Also my grandmother was diagnosed with congestive heart failure in her early

70's and lived to 102 - without too many problems. The heart issue certainly

didn't slow her down.

Good luck.

Kathy

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Thanks Kathy!  I probably needed to hear this last part more than anything

else.  I've been given way to much information on how only 50% make it 5 years

etc.  102 is a great target for me to shoot for.

 Mike McBride

" Failure is not fatal unless you quit; getting knocked down is not embarrassing

unless you allow it to keep you down. " Ashcroft

________________________________

From: pghkathy61 <kambb@...>

Sent: Wednesday, April 29, 2009 8:23:50 AM

Subject: [ ] Re: Xolair and Heart Disease

Mike,

<snip>

Also my grandmother was diagnosed with congestive heart failure in her early

70's and lived to 102 - without too many problems. The heart issue certainly

didn't slow her down.

Good luck.

Kathy

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