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Marilyn Wrote: <<Can a person develop allergy to meds. after being used to taking it for sometime? Why?>>

Well, some of the people where I work said that, yes, that can happen as they have had relatives or friends that that has happened too. No one seems to know why, though. Sorry I couldn't be of more help.

Marilyn Wrote: <<I'm developing rashes to my carbimazole. Should I ignore the red rashes on my chest and continue to take the med? I think I developed already an affinity with it that I don't like to change, I seem to respond with it well...>>

Have you checked the sheet that comes with your med - for possible side effects? If you did and it doesn't mention your particular one, why not

check with your doctor, you may not have to change the med. The doc may simply adjust your dosage. When they've got a good thing going I don't think he or she will want to change your med any more than you do. <big grin> By the way, are you *sure* it's the med? Sometimes stuff happens and we think it's related when it's not ...

I'll never forget the time I went out in the woods and later developed a fever, chills, and was sick with something. I noticed I had a faint red rash on my back and chest so I went to the doc and he thought it was related to my illness. But guess what? During my forest trek I had brushed against a plant. You can guess the rest but there's *still* another surprise. By the time things had escalated to angry red welts on the top of my foot working up my leg and I made a trip back to the doc, it turned out that the plant I brushed against wasn't poison oak or sumac or any of the common poisonous plants at all. The doc told me that I had an allergic reaction to this particular plant which was nonpoisonous to anyone else. So sometimes are bouts of logic are legit and sometimes not. <laughing out loud>

Warmly,

Denim

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Marilyn,

With allergy, the cumulative effect can make an allergy worse. This is why

those of us with food allergy use the " rotation diet " to keep from developing

more allergy from having the same food over and over. I don't know specifically

why it happens. Please check with your dr ASAP. It may be nothing, but I'd

worry about it getting to anaphlaxis (spelling?).

Marcia

hyperthyroidism wrote:

__

Message: 5

Date: Sun, 25 Feb 2001 07:27:23 -0800 (PST)

From: marilyn manzo

Subject: allergy

CAn a person develop allergy to medz after being used

to taking it for sometime? Why?

I'm developing rashes to my carbimazole. Should I

ignore the red rashes on my chest and continue to take

the med? I think I developed already an affinity with

it that I don't like to change, I seem to rspond with

it well...

marilyn

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Many allergies are triggered by exercise. Called " exercise induced

allergies, " they occur with food or drugs. In my case I can eat cooked celery

with no problems. If I eat celery before aerobics, though, I have

exercise-induced allergic symptoms, including hives, that have twice led to

anaphylaxis. I've also had this happen with bee pollen. Some asthmatics have

this problem too and only experience drug or food induced wheezing attacks

after excersing. You may just have to time your dose so it's as far apart as

possible from the time you exercise.

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I don't know why, when I take the med in the morning..

no rash.. when I take it after running round the oval

and after 4hours past that exercise, the rashes

appear... for me it's just a little itch, but I'll

observe some more.. thanks..

--- marcia21@... wrote:

> Marilyn,

> With allergy, the cumulative effect can make an

> allergy worse. This is why those of us with food

> allergy use the " rotation diet " to keep from

> developing more allergy from having the same food

> over and over. I don't know specifically why it

> happens. Please check with your dr ASAP. It may be

> nothing, but I'd worry about it getting to

> anaphlaxis (spelling?).

> Marcia

>

>

> hyperthyroidism wrote:

> __

>

> Message: 5

> Date: Sun, 25 Feb 2001 07:27:23 -0800 (PST)

> From: marilyn manzo

> Subject: allergy

>

> CAn a person develop allergy to medz after being

> used

> to taking it for sometime? Why?

>

> I'm developing rashes to my carbimazole. Should I

> ignore the red rashes on my chest and continue to

> take

> the med? I think I developed already an affinity

> with

> it that I don't like to change, I seem to rspond

> with

> it well...

>

> marilyn

>

>

__________________________________________________

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I don't know why, when I take the med in the morning..

no rash.. when I take it after running round the oval

and after 4hours past that exercise, the rashes

appear... for me it's just a little itch, but I'll

observe some more.. thanks.. marilyn

--- marcia21@... wrote:

> Marilyn,

> With allergy, the cumulative effect can make an

> allergy worse. This is why those of us with food

> allergy use the " rotation diet " to keep from

> developing more allergy from having the same food

> over and over. I don't know specifically why it

> happens. Please check with your dr ASAP. It may be

> nothing, but I'd worry about it getting to

> anaphlaxis (spelling?).

> Marcia

>

>

> hyperthyroidism wrote:

> __

>

> Message: 5

> Date: Sun, 25 Feb 2001 07:27:23 -0800 (PST)

> From: marilyn manzo

> Subject: allergy

>

> CAn a person develop allergy to medz after being

> used

> to taking it for sometime? Why?

>

> I'm developing rashes to my carbimazole. Should I

> ignore the red rashes on my chest and continue to

> take

> the med? I think I developed already an affinity

> with

> it that I don't like to change, I seem to rspond

> with

> it well...

>

> marilyn

>

>

__________________________________________________

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Thanks Elaine, I've never heard of drug-induced

allergies before but most probably mine is. Since I

can't exercise most often, I only saw the rashes come

out twice and those were after the exercise.

I hope yours doesn't bother you much now.

marilyn

--- daisyelaine@... wrote:

> Many allergies are triggered by exercise. Called

> " exercise induced

> allergies, " they occur with food or drugs. In my

> case I can eat cooked celery

> with no problems. If I eat celery before aerobics,

> though, I have

> exercise-induced allergic symptoms, including hives,

> that have twice led to

> anaphylaxis. I've also had this happen with bee

> pollen. Some asthmatics have

> this problem too and only experience drug or food

> induced wheezing attacks

> after excersing. You may just have to time your dose

> so it's as far apart as

> possible from the time you exercise.

>

__________________________________________________

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Marilyn

It could be a reaction to your perspiration - and not related to the

medication at all....

marilyn manzo wrote:

> I don't know why, when I take the med in the morning..

> no rash.. when I take it after running round the oval

> and after 4hours past that exercise, the rashes

> appear... for me it's just a little itch, but I'll

> observe some more.. thanks.. marilyn

>

> --- marcia21@... wrote:

> > Marilyn,

> > With allergy, the cumulative effect can make an

> > allergy worse. This is why those of us with food

> > allergy use the " rotation diet " to keep from

> > developing more allergy from having the same food

> > over and over. I don't know specifically why it

> > happens. Please check with your dr ASAP. It may be

> > nothing, but I'd worry about it getting to

> > anaphlaxis (spelling?).

> > Marcia

> >

> >

> > hyperthyroidism wrote:

> > __

> >

> > Message: 5

> > Date: Sun, 25 Feb 2001 07:27:23 -0800 (PST)

> > From: marilyn manzo

> > Subject: allergy

> >

> > CAn a person develop allergy to medz after being

> > used

> > to taking it for sometime? Why?

> >

> > I'm developing rashes to my carbimazole. Should I

> > ignore the red rashes on my chest and continue to

> > take

> > the med? I think I developed already an affinity

> > with

> > it that I don't like to change, I seem to rspond

> > with

> > it well...

> >

> > marilyn

> >

> >

>

> __________________________________________________

>

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  • 2 years later...

Dr. Goldburg makes me give my little guy 1 teaspoon of claritan 24hres every

night before bed this helps alot.

sue1jeff2001 <jeffb@...> wrote:

my 5 year old wakes up with a little bit f congestion in the morning,

later in the day it turns runny. shoul di use a decongestant or

antihistamine ? dimetapp has a product with both. thanks

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I have a 7 and 4 year old, my 7 year old has really bad allergies. They

manifest in seizures and stomach problems. We had his histamine checked during

stomach aches and seizures and found his levels to be really high. His

allergies are cyclical and last time his pedi who is somewhat willing to try

different things told us to give him benadryl and pepcid to block the histamine,

sounds strange but 4 days of seizures and stomach aches ceased within one hour

of giving him his first dose of both meds. Other doctors look at me very

strange when I tell them, those of us with these kids are just too wigged out

for the mainstream. I sometimes wish a doctor would say if it worked for your

son then that is a move in the right direction.

TAMMY <tammyblanchette2002@...> wrote:Dr. Goldburg makes me give my little

guy 1 teaspoon of claritan 24hres every night before bed this helps alot.

sue1jeff2001 <jeffb@...> wrote:

my 5 year old wakes up with a little bit f congestion in the morning,

later in the day it turns runny. shoul di use a decongestant or

antihistamine ? dimetapp has a product with both. thanks

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Dr G suggested to us last winter to use Triaminic Nighttime. It has

a decongestant antihistamine and cough suppressant, and it allows the

little ones to sleep.

> my 5 year old wakes up with a little bit f congestion in the

morning,

> later in the day it turns runny. shoul di use a decongestant or

> antihistamine ? dimetapp has a product with both. thanks

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In a message dated 11/14/03 9:46:10 AM Central Standard Time,

tparker82@... writes:

> I had my son's allergies removed with a western noninvasive technique

> called NAET.

Both my son and I have also had numerous allergies cleared with NAET -- or

rather a combo of NAET and TBM that our doc uses. We've not only seen a

disappearance of previous symptoms from various foods and inhalants, but also

saw

changes in IgE and IgG blood work and in p/n allergy testing results. However,

my son's EOS counts and CD3 and CD4 numbers are still really high. Since we

didn't run the CDs prior to the NAET/TBM, I have no reference range, but the EOS

numbers have remained fairly consistently high no matter how healthy he seems

or how many foods we remove. Did you test your child's EOS (on a CBC) prior

to NAET and more recently?

Gaylen

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I had my son's allergies removed with a western noninvasive technique called

NAET. It sounds weird but it worked. A lot of behavioral improvements as we

removed 39 allergies. They also tested him for sensitivities to meds and

cleared him of those. They have a protocol of clearing and they treated him for

2 allergies per week. So it took about 20 weeks. They have a website with

info. and a list of practitioners. It seems like voodoo but my son had his

first formed stools in his life afterwards and used called the doctor by his

name when he wasn't using names. Good luck.

Re: allergy

I have a 7 and 4 year old, my 7 year old has really bad allergies. They

manifest in seizures and stomach problems. We had his histamine checked during

stomach aches and seizures and found his levels to be really high. His

allergies are cyclical and last time his pedi who is somewhat willing to try

different things told us to give him benadryl and pepcid to block the histamine,

sounds strange but 4 days of seizures and stomach aches ceased within one hour

of giving him his first dose of both meds. Other doctors look at me very

strange when I tell them, those of us with these kids are just too wigged out

for the mainstream. I sometimes wish a doctor would say if it worked for your

son then that is a move in the right direction.

TAMMY <tammyblanchette2002@...> wrote:Dr. Goldburg makes me give my

little guy 1 teaspoon of claritan 24hres every night before bed this helps alot.

sue1jeff2001 <jeffb@...> wrote:

my 5 year old wakes up with a little bit f congestion in the morning,

later in the day it turns runny. shoul di use a decongestant or

antihistamine ? dimetapp has a product with both. thanks

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> my 5 year old wakes up with a little bit f congestion in the

morning,

> later in the day it turns runny. shoul di use a decongestant or

> antihistamine ? dimetapp has a product with both. thanks

>

>

>

>

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Where can I find the website info. Can you give me a link to it?

>From: " Tracey " <tparker82@...>

>Reply-

>< >

>Subject: Re: allergy

>Date: Fri, 14 Nov 2003 09:20:54 -0500

>

>I had my son's allergies removed with a western noninvasive technique

>called NAET. It sounds weird but it worked. A lot of behavioral

>improvements as we removed 39 allergies. They also tested him for

>sensitivities to meds and cleared him of those. They have a protocol of

>clearing and they treated him for 2 allergies per week. So it took about

>20 weeks. They have a website with info. and a list of practitioners. It

>seems like voodoo but my son had his first formed stools in his life

>afterwards and used called the doctor by his name when he wasn't using

>names. Good luck.

> Re: allergy

>

>

> I have a 7 and 4 year old, my 7 year old has really bad allergies. They

>manifest in seizures and stomach problems. We had his histamine checked

>during stomach aches and seizures and found his levels to be really high.

>His allergies are cyclical and last time his pedi who is somewhat willing

>to try different things told us to give him benadryl and pepcid to block

>the histamine, sounds strange but 4 days of seizures and stomach aches

>ceased within one hour of giving him his first dose of both meds. Other

>doctors look at me very strange when I tell them, those of us with these

>kids are just too wigged out for the mainstream. I sometimes wish a doctor

>would say if it worked for your son then that is a move in the right

>direction.

>

> TAMMY <tammyblanchette2002@...> wrote:Dr. Goldburg makes me give my

>little guy 1 teaspoon of claritan 24hres every night before bed this helps

>alot.

>

>

> sue1jeff2001 <jeffb@...> wrote:

> my 5 year old wakes up with a little bit f congestion in the morning,

> later in the day it turns runny. shoul di use a decongestant or

> antihistamine ? dimetapp has a product with both. thanks

>

>

>

>

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Bella,

Dr. Devi S. Nambudripad, D.C., L.Ac., R.N., Ph.D. is the author of a book called

" Say Good-Bye to Allergy-Related Autism. She is the person that came up with

NAET. (My niece gave me this book about a year ago...I still have not made time

to read it).

I think she uses alternative medicine, and kinesiology, so you may want to check

with Dr. Golberg before you start any treatments that may conflict with the

protocol.

Good luck!

Re: allergy

>Date: Fri, 14 Nov 2003 09:20:54 -0500

>

>I had my son's allergies removed with a western noninvasive technique

>called NAET. It sounds weird but it worked. A lot of behavioral

>improvements as we removed 39 allergies. They also tested him for

>sensitivities to meds and cleared him of those. They have a protocol of

>clearing and they treated him for 2 allergies per week. So it took about

>20 weeks. They have a website with info. and a list of practitioners. It

>seems like voodoo but my son had his first formed stools in his life

>afterwards and used called the doctor by his name when he wasn't using

>names. Good luck.

===MESSAGE THREAD TRUNCATED===

Responsibility for the content of this message lies strictly with

the original author, and is not necessarily endorsed by or the

opinion of the Research Institute.

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What are NAET & TBM?????

Thanks

Audra in Louisiana

>From: Googahly@...

>Reply-

>

>Subject: Re: allergy

>Date: Fri, 14 Nov 2003 11:05:06 EST

>

>In a message dated 11/14/03 9:46:10 AM Central Standard Time,

>tparker82@... writes:

>

>

> > I had my son's allergies removed with a western noninvasive technique

> > called NAET.

>

>Both my son and I have also had numerous allergies cleared with NAET -- or

>rather a combo of NAET and TBM that our doc uses. We've not only seen a

>disappearance of previous symptoms from various foods and inhalants, but

>also saw

>changes in IgE and IgG blood work and in p/n allergy testing results.

>However,

>my son's EOS counts and CD3 and CD4 numbers are still really high. Since

>we

>didn't run the CDs prior to the NAET/TBM, I have no reference range, but

>the EOS

>numbers have remained fairly consistently high no matter how healthy he

>seems

>or how many foods we remove. Did you test your child's EOS (on a CBC)

>prior

>to NAET and more recently?

>Gaylen

>

>

>

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Thanks a lot. I have an appointment with him next week and I will check it

out.

>From: " golivo " <golivo@...>

>Reply-

>< >

>Subject: Re: allergy

>Date: Fri, 14 Nov 2003 09:09:35 -0800

>

>Bella,

>

>Dr. Devi S. Nambudripad, D.C., L.Ac., R.N., Ph.D. is the author of a book

>called " Say Good-Bye to Allergy-Related Autism. She is the person that

>came up with NAET. (My niece gave me this book about a year ago...I still

>have not made time to read it).

>I think she uses alternative medicine, and kinesiology, so you may want to

>check with Dr. Golberg before you start any treatments that may conflict

>with the protocol.

>

>Good luck!

> Re: allergy

> >Date: Fri, 14 Nov 2003 09:20:54 -0500

> >

> >I had my son's allergies removed with a western noninvasive technique

> >called NAET. It sounds weird but it worked. A lot of behavioral

> >improvements as we removed 39 allergies. They also tested him for

> >sensitivities to meds and cleared him of those. They have a protocol

>of

> >clearing and they treated him for 2 allergies per week. So it took

>about

> >20 weeks. They have a website with info. and a list of practitioners.

>It

> >seems like voodoo but my son had his first formed stools in his life

> >afterwards and used called the doctor by his name when he wasn't using

> >names. Good luck.

>

>===MESSAGE THREAD TRUNCATED===

>

> Responsibility for the content of this message lies strictly with

> the original author, and is not necessarily endorsed by or the

> opinion of the Research Institute.

>

>

_________________________________________________________________

Frustrated with dial-up? Get high-speed for as low as $26.95.

https://broadband.msn.com (Prices may vary by service area.)

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I saw changes in IgE and IgG. I Do still avoid gluten and dairy because of

their opiate effect. I think it helped immensely with meds and environmental

sensitivities.

Re: allergy

In a message dated 11/14/03 9:46:10 AM Central Standard Time,

tparker82@... writes:

> I had my son's allergies removed with a western noninvasive technique

> called NAET.

Both my son and I have also had numerous allergies cleared with NAET -- or

rather a combo of NAET and TBM that our doc uses. We've not only seen a

disappearance of previous symptoms from various foods and inhalants, but also

saw

changes in IgE and IgG blood work and in p/n allergy testing results.

However,

my son's EOS counts and CD3 and CD4 numbers are still really high. Since we

didn't run the CDs prior to the NAET/TBM, I have no reference range, but the

EOS

numbers have remained fairly consistently high no matter how healthy he seems

or how many foods we remove. Did you test your child's EOS (on a CBC) prior

to NAET and more recently?

Gaylen

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www.naet.com You can also do a search on naet and will

find other info. I don't know why any doctor would find fault with this. Their

are no needles or drugs. They simply do massage on meridian points. I

mentioned in another post that I still advocate GFCF diet unless your labs show

opiate effect is not a problem. I also failed to mention that my son's dark

under eye circles went away and energy went way up. Most doctors I talked to

said they did not see how it could work but would not hurt. A friend of mine

also treated her son with naet with great results and no longer does diet with

her son. Her father in law also tried it with a life threatening allergy to

shellfish and now consumes all the shellfish he wants!

Re: allergy

>

>

> I have a 7 and 4 year old, my 7 year old has really bad allergies. They

>manifest in seizures and stomach problems. We had his histamine checked

>during stomach aches and seizures and found his levels to be really high.

>His allergies are cyclical and last time his pedi who is somewhat willing

>to try different things told us to give him benadryl and pepcid to block

>the histamine, sounds strange but 4 days of seizures and stomach aches

>ceased within one hour of giving him his first dose of both meds. Other

>doctors look at me very strange when I tell them, those of us with these

>kids are just too wigged out for the mainstream. I sometimes wish a doctor

>would say if it worked for your son then that is a move in the right

>direction.

>

> TAMMY <tammyblanchette2002@...> wrote:Dr. Goldburg makes me give my

>little guy 1 teaspoon of claritan 24hres every night before bed this helps

>alot.

>

>

> sue1jeff2001 <jeffb@...> wrote:

> my 5 year old wakes up with a little bit f congestion in the morning,

> later in the day it turns runny. shoul di use a decongestant or

> antihistamine ? dimetapp has a product with both. thanks

>

>

>

>

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Some already know this....for others it may come as a surprise.

NAET was one of the alternative treatments we tried prior to finding Dr. G.

I was open to anything that could help, as long as I knew it couldn't hurt.

I even called Devi for a recommendation. I wanted to find someone very

experienced and there was nobody in my area doing this .

I completely committed to the treatment. You'd have to in order to travel

several hours, one-way, a couple times a week, for months and months. We

also were working with two of the best according to Devi. One was an M.D.,

the other was oriental medicine. The M.D. was a little further away, so we

saw her about once a month. It gave us the added benefit of seeing if there

was agreement on what had cleared.

Those who have experience with this type of treatment will have a good idea

what we committed $$$-wise.... clearing over 40 items.

For whatever reason, we had no long term benefits. The symptoms and

bloodtests indicated that his immune system was still reacting to

everything he'd been treated for.

Our experience doesn't necessarily mean that someone else can't have a

positive experience. At least with this type of alternative treatment there

doesn't appear to be any dangers/potential damage involved. The only

potential negative (in my opinion) is time and money since you have to

commit to it if you go that route.

Cheryl

P.S.- the opiate effect was a theory. Research is showing immune reactions.

----Original Message Follows----

From: " Tracey " <tparker82@...>

Reply-

< >

Subject: Re: allergy

Date: Fri, 14 Nov 2003 14:54:30 -0500

I saw changes in IgE and IgG. I Do still avoid gluten and dairy because of

their opiate effect. I think it helped immensely with meds and

environmental sensitivities.

_________________________________________________________________

MSN Shopping upgraded for the holidays! Snappier product search...

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> Some already know this....for others it may come as a surprise.

>

> NAET was one of the alternative treatments we tried prior to

finding Dr. G.

> I was open to anything that could help, as long as I knew it

couldn't hurt.

> I even called Devi for a recommendation. I wanted to find someone

very

> experienced and there was nobody in my area doing this .

>

> I completely committed to the treatment. You'd have to in order to

travel

> several hours, one-way, a couple times a week, for months and

months. We

> also were working with two of the best according to Devi. One was

an M.D.,

> the other was oriental medicine. The M.D. was a little further

away, so we

> saw her about once a month. It gave us the added benefit of seeing

if there

> was agreement on what had cleared.

>

> Those who have experience with this type of treatment will have a

good idea

> what we committed $$$-wise.... clearing over 40 items.

>

> For whatever reason, we had no long term benefits. The symptoms

and

> bloodtests indicated that his immune system was still reacting to

> everything he'd been treated for.

>

> Our experience doesn't necessarily mean that someone else can't

have a

> positive experience. At least with this type of alternative

treatment there

> doesn't appear to be any dangers/potential damage involved. The

only

> potential negative (in my opinion) is time and money since you have

to

> commit to it if you go that route.

> Cheryl

>

> P.S.- the opiate effect was a theory. Research is showing immune

reactions.

>

> ----Original Message Follows----

> From: " Tracey " <tparker82@n...>

> Reply-

> < >

> Subject: Re: allergy

> Date: Fri, 14 Nov 2003 14:54:30 -0500

>

> I saw changes in IgE and IgG. I Do still avoid gluten and dairy

because of

> their opiate effect. I think it helped immensely with meds and

> environmental sensitivities.

> what do u mean by your ps?

> _________________________________________________________________

> MSN Shopping upgraded for the holidays! Snappier product search...

> http://shopping.msn.com

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Sorry you had no long term benefit for your efforts. Opiate effect is based on

lab work conducted by Dr. Cave from AAL Lab urinary polypeptide test.

When we saw Dr. Cave she felt diet was still important but I produced labs

showing no allergies to Ige, IgA, or IGG. The polypeptide test showed me he

needed the diet. He had one goldfish this summer and was a totally different

child. High as a kite and unsafe in his judgement which had is normally good.

> Some already know this....for others it may come as a surprise.

>

> NAET was one of the alternative treatments we tried prior to

finding Dr. G.

> I was open to anything that could help, as long as I knew it

couldn't hurt.

> I even called Devi for a recommendation. I wanted to find someone

very

> experienced and there was nobody in my area doing this .

>

> I completely committed to the treatment. You'd have to in order to

travel

> several hours, one-way, a couple times a week, for months and

months. We

> also were working with two of the best according to Devi. One was

an M.D.,

> the other was oriental medicine. The M.D. was a little further

away, so we

> saw her about once a month. It gave us the added benefit of seeing

if there

> was agreement on what had cleared.

>

> Those who have experience with this type of treatment will have a

good idea

> what we committed $$$-wise.... clearing over 40 items.

>

> For whatever reason, we had no long term benefits. The symptoms

and

> bloodtests indicated that his immune system was still reacting to

> everything he'd been treated for.

>

> Our experience doesn't necessarily mean that someone else can't

have a

> positive experience. At least with this type of alternative

treatment there

> doesn't appear to be any dangers/potential damage involved. The

only

> potential negative (in my opinion) is time and money since you have

to

> commit to it if you go that route.

> Cheryl

>

> P.S.- the opiate effect was a theory. Research is showing immune

reactions.

>

Responsibility for the content of this message lies strictly with

the original author, and is not necessarily endorsed by or the

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----Original Message Follows----

From: " Tracey " <tparker82@...>

Reply-

< >

Subject: Re: Re: allergy

Date: Fri, 14 Nov 2003 20:35:32 -0500

>Sorry you had no long term benefit for your efforts. Opiate effect is

>based on lab work conducted by Dr. Cave from AAL Lab urinary

>polypeptide test. When we saw Dr. Cave she felt diet was still >important

>but I produced labs showing no allergies to Ige, IgA, or IGG. The

>polypeptide test showed me he needed the diet. He had one goldfish this

>summer and was a totally different child. High as a kite and unsafe in his

>judgement which had is normally good.

Hi Tracey,

I put together a collection to help explain my comment. If you look back

over the past 5-10 years, a lot has changed. When we first became

patients of Dr. Goldberg I remember not seeing too many others involved with

autism discussing things like neuroimmune, cytokines, etc.

From what I can gather, the opioid theory evolved due to a combination of

findings. The tests I found at AAL, GPL, and discussions from Dr. Cave all

seem to go back to older research when they were trying to connect the brain

dysfunction, reactions to dietary factors, and the urinary findings. And

how to tie this together with the reason they felt these problems were

occuring. I'm assuming the opioid part was because at one time it was

believed that D-amino acids had to come from an exogenous source and opioids

contain D-amino acids.

As you'll see below, the same urinary and serum findings have been discussed

in Lupus. Great Plains has references linking the same findings in autism

and Schizophrenia. There are a ton of abstracts listed in our files section

on schizophrenia and lupus that discuss the immune system, infections, etc.

like the abstracts listed below on autism. I've also posted quite a lot on

immune activation and tryptophan metabolism. (can be found in files section

or by doing a search under 1raptor )

Hope that helps

Cheryl

----------------------------------

(this is from an article on Dr. Cave's theory)

" In addition, the children combine casein from dairy protein and gluten from

wheat, oats, barley, and rye to naturally occurring morphine in the body.

These gliadomorphin and casomorphin peptides make the children spacey and

irritable. The enzyme DPPIV that would normally break down these peptides

and eliminate them is inactivated by mercury and heavy metals. Subsequently,

these children have higher levels of morphines in the body. "

---------------------------------------------

http://www.antibodyassay.com/index.htm

choose urinary peptides and IAG #6500

http://www.greatplainslaboratory.com/glutencasein.html

Dohan, F.C. " Schizophrenia: possible relationship to cereal grains and

celiac disease. In: S. Sankar, ed, Schizophrenia: Current Concepts and

Research. PJD Publications, Hicksville, NY, 1969 Page 539.

Dohan, F. C. " The possible pathogenic effect of cereal grains in

schizophrenia--Celiac disease as a model. " Acta Neurol. 31:195, 1976.

Dohan, F. C. et al. " Relapsed schizophrenics. More rapid improvement on a

milk and cereal-free diet. " Br. J. Psychiatry 115:595, 1969.

Kinivsberg, A. et al. " Dietary Intervention in Autistic Syndromes. " Brain

Dysfunction 3: 315-327, 1990.

Reichelt K. et al. " Gluten, mil proteins and autism: dietary intervention

effects on behavior and peptide secretions. " Journ of Applied Nutrition

42:1-11, 1990.

Reichelt K. et al. " Biologically active peptide-containing fractions in

schizophrenia and childhood autism. " Adv Biochem Psychopharmacol 28:627-47,

1981.

-------------------------------------------------------------

Genetic and physiological data implicating the new human gene G72 and the

gene for D-amino acid oxidase in schizophrenia.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13675-80. Epub 2002 Oct 03.

Erratum in: Proc Natl Acad Sci U S A 2002 Dec 24;99(26):17221.

PMID: 12364586 [PubMed - indexed for MEDLINE]

------------------------

Cloninger CR. Related Articles, Links

The discovery of susceptibility genes for mental disorders.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13365-7. Epub 2002 Oct 08.

Review. No abstract available.

PMID: 12374853 [PubMed - indexed for MEDLINE]

-------------------------

Orig Life Evol Biosph. 2002 Apr;32(2):103-27. Related Articles, Links

D-amino acids in living higher organisms.

Fujii N.

Research Reactor Institute, Kyote University Kumatori, Sennan, Osaka, Japan.

nfujii@...

The homochirality of biological amino acids (L-amino acids) and of the

RNA/DNA backbone (D-ribose) might have become established before the origin

of life. It has been considered that D-amino acids and L-sugars were

eliminated on the primitive Earth. Therefore, the presence and function of

D-amino acids in living organisms have not been studied except for D-amino

acids in the cell walls of microorganisms. However, D-amino acids were

recently found in various living higher organisms in the form of free amino

acids, peptides, and proteins. Free D-aspartate and D-serine are present and

may have important physiological functions in mammals. D-amino acids in

peptides are well known as opioid peptides and neuropeptides. In protein,

D-aspartate residues increase during aging. This review deals with recent

advances in the study of D-amino acids in higher organisms.

Publication Types:

Review

Review, Tutorial

PMID: 12185671 [PubMed - indexed for MEDLINE]

--------------------------------

FEBS Lett. 2003 Sep 25;552(2-3):95-8. Related Articles, Links

D-Amino acids and D-Tyr-tRNA(Tyr) deacylase: stereospecificity of the

translation machine revisited.

Yang H, Zheng G, Peng X, Qiang B, Yuan J.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and

Peking Union Medical College, 5 Dong Dan San Tiao, 100005 Beijing, PR China.

Until 30 years ago, it had been considered that D-amino acids were excluded

from living systems except for D-amino acids in the cell wall of

microorganisms. However, D-amino acids, in the form of free amino acids,

peptides and proteins, were recently detected in various living organisms

from bacteria to mammals. The extensive distribution of bio-functional

D-amino acids challenges the current concept of protein synthesis: more

attention should be paid to the stereospecificity of the translation

machine. Besides aminoacyl-tRNA synthetases, elongation factor Tu and some

other mechanisms, D-Tyr-tRNA(Tyr) deacylases provide a novel checkpoint

since they specifically recycle misaminoacylated D-Tyr-tRNA(Tyr) and some

other D-aminoacyl-tRNAs. Their unique structure represents a new class of

tRNA-dependent hydrolase. These unexpected findings have far-reaching

implications for our understanding of protein synthesis and its origin.

Publication Types:

Review

Review, Tutorial

PMID: 14527667 [PubMed - indexed for MEDLINE]

------------------------------------------------

Dev Med Child Neurol. 2003 Feb;45(2):121-8. Related Articles, Links

Comment in:

Dev Med Child Neurol. 2003 Feb;45(2):75.

Opioid peptides and dipeptidyl peptidase in autism.

Hunter LC, O'Hare A, Herron WJ, Fisher LA, GE.

YAbA Ltd, Logan Building, Roslin Biocentre, Midlothian, UK.

It has been hypothesized that autism results from an 'opioid peptide

excess'. The aims of this study were to (1) confirm the presence of opioid

peptides in the urine of children with autism and (2) determine whether

dipeptidyl peptidase IV (DPPIV/CD26) is defective in children with autism.

Opioid peptides were not detected in either the urine of children with

autism (10 children; nine males, one female; age range 2 years 6 months to

10 years 1 month) or their siblings (10 children; seven males, three

females; age range 2 years 3 months to 12 years 7 months) using liquid

chromatography-ultraviolet-mass spectrometric analysis (LC-UV-MS). Plasma

from 11 normally developing adults (25 years 5 months to 55 years 5 months)

was also tested. The amount and activity of DPPIV in the plasma were

quantified by an ELISA and DPPIV enzyme assay respectively; DPPIV was not

found to be defective. The percentage of mononuclear cells expressing DPPIV

(as CD26) was determined by flow cytometry. Children with autism had a

significantly lower percentage of cells expressing CD3 and CD26, suggesting

that they had lower T-cell numbers than their siblings. In conclusion, this

study failed to replicate the findings of others and questions the validity

of the opioid peptide excess theory for the cause of autism.

PMID: 12578238 [PubMed - indexed for MEDLINE]

---------------------------------------------

J Rheumatol. 2002 Sep;29(9):1858-66. Related Articles, Links

Reduction of serum soluble CD26/dipeptidyl peptidase IV enzyme activity and

its correlation with disease activity in systemic lupus erythematosus.

Kobayashi H, Hosono O, Mimori T, Kawasaki H, Dang NH, Tanaka H, Morimoto C.

Division of Clinical Immunology, Advanced Clinical Research Center,

Institute of Medical Science, University of Tokyo, Japan.

OBJECTIVE: CD26 is the cell surface activation antigen with dipeptidyl

peptidase IV (DPPIV) enzyme activity at the extracellular domain that is

preferentially expressed on memory T cells and has a role in T cell immune

responses. The soluble form of CD26 is present in serum and recombinant

soluble CD26 (rsCD26) can enhance in vitro antigen-specific T cell

responses. To determine the role of soluble CD26 (sCD26) in the

pathophysiology of patients with systemic lupus erythematosus (SLE), we

measured levels of sCD26 and its specific DPPIV activity in serum. METHODS:

Serum sCD26 levels and DPPIV activity were measured by sandwich ELISA in 53

patients with SLE and 54 healthy controls. Serum sCD26 was identified by

immunoprecipitation and immunoblot analysis. Expression of CD26 on T cells

was analyzed by flow cytometry. RESULTS: Serum levels of sCD26 and its

specific DPPIV activity were significantly decreased in SLE and were

inversely correlated with SLE disease activity index score, but not with

clinical variables or clinical subsets of SLE. Close correlation between

sCD26/DPPIV and disease activity was observed in the longitudinal study.

CONCLUSION: Serum levels of sCD26 may be involved in the pathophysiology of

SLE, and appear to be useful as a new disease activity measure for SLE.

PMID: 12233879 [PubMed - indexed for MEDLINE]

----------------------------------------

Bull G, Shattock P, Whiteley P, R, Groundwater PW, Lough JW, Lees

G. Related Articles,

Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for

autism spectrum disorders.

Med Sci Monit. 2003 Oct;9(10):CR422-5.

PMID: 14523330 [PubMed - in process]

------------------------------

Clin Chim Acta. 1975 Nov 3;64(3):273-80. Related Articles, Links

Urinary excretion of indolyl-3-acryloylglycine in some skin affections.

Marklova E, Malina L, Hais IM.

1. Urinary excretion of indolyl-3-acryloylglycine (chromogen of the

so-called Kimmig's light band) in 15 normal subjects was highly

significantly increased in June-September ( " summer " ) against the

November-April ( " winter " ) collection in the same subjects. Possible

explanation of this phenomenon is discussed. 2. In the " winter " period, the

mean of 23 patients with chronic polymorphous light eruption was

significantly higher than the mean of the 29 controls. In the " summer "

period, though an increaes of the average against " winter " was also noted,

this difference against the control group (29) disappeared. 3. In 24

patients with skin tuberculosis the mean excretion in " winter " was

significantly higher than in controls. This increase cannot be simply

attributed to heliotherapy. 4. In " winter " , there was no significant

difference between the normal subjects and 12 patients with lupus

erythematosus and 10 patients with porphyria cutanea tarda. In both these

groups there was marked " summer " increase in excretion, though in the case

of porphyria cutanea tarda, the " summer " mean was significantly lower than

that of the controls. 5. All results were expressed on creatinine basis. In

part of the subjects it was possible to calculate the excretion per unit

time. Identical conclusions could be drawn.

PMID: 1183041 [PubMed - indexed for MEDLINE]

--------------------------------------------------------------------------------\

-----------------------------------------------

Neurobiol Dis. 2002 Mar;9(2):107-25. Related Articles, Links

Erratum in:

Neurobiol Dis 2002 Jun;10(1):69.

Genetic and immunologic considerations in autism.

Korvatska E, Van de Water J, Anders TF, Gershwin ME.

Division of Rheumatology, Allergy, and Clinical Immunology, University of

California at , , California 95616, USA.

According to recent epidemiological surveys, autistic spectrum disorders

have become recognized as common childhood psychopathologies. These

life-lasting conditions demonstrate a strong genetic determinant consistent

with a polygenic mode of inheritance for which several autism susceptibility

regions have been identified.

Parallel evidence of immune abnormalities in autistic patients argues for an

implication of the immune system in pathogenesis. This review summarizes

advances in the molecular genetics of autism, as well as recently emerging

concerns addressing the disease incidence and triggering factors.

The neurochemical and immunologic findings are analyzed in the context of a

neuroimmune hypothesis for autism. Studies of disorders with established

neuroimmune nature indicate multiple pathways of the pathogenesis; herein,

we discuss evidence of similar phenomena in autism. ©2002 Elsevier Science

(USA).

Publication Types:

Review

Review Literature

PMID: 11895365 [PubMed - indexed for MEDLINE]

--------------------------------------------------------------------

Vojdani A, AW, Anyanwu E, Kashanian A, Bock K, Vojdani E. Related

Articles, Links

Antibodies to neuron-specific antigens in children with autism: possible

cross-reaction with encephalitogenic proteins from milk, Chlamydia

pneumoniae and Streptococcus group A.

J Neuroimmunol. 2002 Aug;129(1-2):168-77. Erratum in: J Neuroimmunol 2002

Sep;130(1-2):248.

PMID: 12161033 [PubMed - indexed for MEDLINE]

-------------------------------

Jyonouchi H, Sun S, Itokazu N. Related Articles, Links

Innate immunity associated with inflammatory responses and cytokine

production against common dietary proteins in patients with autism spectrum

disorder.

Neuropsychobiology. 2002;46(2):76-84.

PMID: 12378124 [PubMed - indexed for MEDLINE]

------------------------------------------

: Croonenberghs J, Bosmans E, Deboutte D, Kenis G, Maes M. Related

Articles, Links

Activation of the inflammatory response system in autism.

Neuropsychobiology. 2002;45(1):1-6.

PMID: 11803234 [PubMed - indexed for MEDLINE]

---------------------------------

Jyonouchi H, Sun S, Le H. Related Articles, Links

Proinflammatory and regulatory cytokine production associated with innate

and adaptive immune responses in children with autism spectrum disorders and

developmental regression.

J Neuroimmunol. 2001 Nov 1;120(1-2):170-9.

PMID: 11694332 [PubMed - indexed for MEDLINE]

------------------------------------

AR, Maciulis A, Odell D. Related Articles, Links

The association of MHC genes with autism.

Front Biosci. 2001 Aug 1;6:D936-43. Review.

PMID: 11487481 [PubMed - indexed for MEDLINE]

--------------------------------

Gupta S, Aggarwal S, Rashanravan B, Lee T. Related Articles, Links

Th1- and Th2-like cytokines in CD4+ and CD8+ T cells in autism.

J Neuroimmunol. 1998 May 1;85(1):106-9.

PMID: 9627004 [PubMed - indexed for MEDLINE

---------------------------

:Mittleman BB, Castellanos FX, sen LK, Rapoport JL, Swedo SE, Shearer

GM. Related Articles, Links

Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease.

J Immunol. 1997 Sep 15;159(6):2994-9.

PMID: 9300724 [PubMed - indexed for MEDLINE]

---------------------------------------

Jyonouchi H, Sun S, Itokazu N. Related Articles, Links

Innate immunity associated with inflammatory responses and cytokine

production against common dietary proteins in patients with autism spectrum

disorder.

Neuropsychobiology. 2002;46(2):76-84.

PMID: 12378124 [PubMed - indexed for MEDLINE]

-------------------------

PH. Related Articles, Links

Maternal infection: window on neuroimmune interactions in fetal brain

development and mental illness.

Curr Opin Neurobiol. 2002 Feb;12(1):115-8.

PMID: 11861174 [PubMed - indexed for MEDLINE]

-------------------

Hornig M, Solbrig M, Horscroft N, Weissenbock H, Lipkin WI. Related

Articles, Links

Borna disease virus infection of adult and neonatal rats: models for

neuropsychiatric disease.

Curr Top Microbiol Immunol. 2001;253:157-77.

PMID: 11417134 [PubMed - indexed for MEDLINE]

-----------------

Hornig M, Weissenbock H, Horscroft N, Lipkin WI. Related Articles, Links

An infection-based model of neurodevelopmental damage.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12102-7.

PMID: 10518583 [PubMed - indexed for MEDLINE

-------------------

Sakic B, Szechtman H, Denburg JA. Related Articles, Links

Neurobehavioral alterations in autoimmune mice.

Neurosci Biobehav Rev. 1997 May;21(3):327-40. Review.

PMID: 9168268 [PubMed - indexed for MEDLINE]

_________________________________________________________________

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Thanks for the info. I have tried enzymes Houston and Kirkman and don't see

much help. For my son " theory " seems to make sense. Are you doing diet?

Do you feel there is value in enzymes and if so how do you dose and which brand

do you like. I am new to this site but am interested in lots of different

viewpoints. I follow my instincts, keep my ear to the ground and discuss

options with our Dan doctor. I also find Dorfman really insightful. Did

you try AIT? Our son benefited a great deal from this therapy. He loves the

computer and I am considering earobics or Fast Foreword. I would love input

from anyone who has experience. Thanks again.

Re: Re: allergy

Hi Tracey,

I put together a collection to help explain my comment. If you look back

over the past 5-10 years, a lot has changed. When we first became

patients of Dr. Goldberg I remember not seeing too many others involved with

autism discussing things like neuroimmune, cytokines, etc.

From what I can gather, the opioid theory evolved due to a combination of

findings. The tests I found at AAL, GPL, and discussions from Dr. Cave all

seem to go back to older research when they were trying to connect the brain

dysfunction, reactions to dietary factors, and the urinary findings. And

how to tie this together with the reason they felt these problems were

occuring. I'm assuming the opioid part was because at one time it was

believed that D-amino acids had to come from an exogenous source and opioids

contain D-amino acids.

As you'll see below, the same urinary and serum findings have been discussed

in Lupus. Great Plains has references linking the same findings in autism

and Schizophrenia. There are a ton of abstracts listed in our files section

on schizophrenia and lupus that discuss the immune system, infections, etc.

like the abstracts listed below on autism. I've also posted quite a lot on

immune activation and tryptophan metabolism. (can be found in files section

or by doing a search under 1raptor )

Hope that helps

Cheryl

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