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My teenage daughter began xolair treatments in October 2007 for

severe allergic asthma. By Spring 2008, even her neurological issues

(chronic nerve pain, seizures, migraines) had improved significantly.

She has battled some illness the past few months, but nothing severe.

She received her December injections on Tues, Dec 9. She woke up

dizzy on Weds, and she fell in the bathroom - did not hit her head.

Since this time, she has suffered from significant memory lapses -

many times each day. Within a couple of weeks of this, she was

experiencing severe mood swings. This past weekend, she began having

minor hallucinations; the mental fuzziness is still quite severe. She

feels " dumb " and " fuzzy " - she has always been a bright, well-

adjusted girl. It has only been the past two days that she has seemed

like her old self again ... she has had a few episodes, but nothing

compared to what has taken place over the past month.

Initially, her immunologist said it appeared to be a reaction to the

xolair. The did a 48 hr. video EEG to rule out seizures. Now that we

are at the point for her Jan injections, her immunologist says he

doesn't think that the xolair has anything at all to do with these

symptoms.

Her neurologist has encouraged me to make an appointment with a

psychiatrist, as she is dealing with a chemical imbalance. These

symptoms STARTED just 12 hrs after her 14th xolair injections. We

have an appt on Jan 20th with a psychiatrist, but I am concerned

about getting injections before we meet with him to learn his

opinions re: xolair triggering this reaction.

Please ... if anyone in this group has experienced anything similar,

I would greatly appreciate any input. This drug is still so new that

information is limited. I have often referred to it as the " wonder

drug that gave me my daughter back. " Unfortunately, we are now

concerned that it has somehow had the opposite effect!

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