Exercise-induced anaphylaxis

[Guest guest]

Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

When this happens to me at the gym, I immediately take two Benedryl, slow my run

to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

I'm just looking for others who may have the exercise-induced anaphylaxis. If

so, has Xolair helped you with this?!

Thank you for your time.

[Guest guest]

Coop,

I read your letter and been wondering about other possible causes. While this

only happens when you work out, I am wondering if you might have some type of

latex or similar type reaction to your equipment. Is it possible that your

running shoes or workout clothes may be causing this? Is this the only time you

wear those shoes and clothes? Also, maybe the treadmill or energy drink? I m

thinking its something other than exercise itself.

On Mon Mar 15th, 2010 6:09 PM EDT coop0919 wrote:

>Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

>

>When this happens to me at the gym, I immediately take two Benedryl, slow my

run to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

>

>I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

>

>My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

>

>I'm just looking for others who may have the exercise-induced anaphylaxis. If

so, has Xolair helped you with this?!

>

>Thank you for your time.

>

>

>

>

>------------------------------------

>

>

[Guest guest]

Hi Mark,

Yes, it only happens when I run. It's gotten progressively worse over the years.

Three years ago I could run four hard miles and not have any issue. Now, I have

to keep it to three and I can't run very hard or I will definitely have a

reaction. I wear the clothing and shoes at other times, so it isn't that. It's

definitely exercise-induced anaphylaxis, as I've had two different allergists

diagnose it as that and I've done extensive research on it. I'm just wondering

if Xolair will help with this, as it helps with other allergies. I'm desperate

to talk to anyone else who suffers from this and compare notes. Maybe they know

of something that helps.

Thank you for reading though and if you hear of anyone, will you please send

them my way?

Thanks so much! :-)

>

> >Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

> >

> >When this happens to me at the gym, I immediately take two Benedryl, slow my

run to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

> >

> >I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

> >

> >My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

> >

> >I'm just looking for others who may have the exercise-induced anaphylaxis. If

so, has Xolair helped you with this?!

> >

> >Thank you for your time.

> >

> >

> >

> >

> >------------------------------------

> >

> >

[Guest guest]

Coop,

Good luck. I have been taking Xolair shots for about 3 months now. It has been

miraculous for me with its affects.. I now get on the eliptical for 45 minutes

at a time, ski out west at 9000 feet and play tennis. All in all it has really

been a Godsend. I haven t started discussions with my doc about weening off my

asthma meds, but haven t had to take any steroids as in the past. I was

fortunate to have pretty fast results. Good luck

On Mon Mar 15th, 2010 10:15 PM EDT coop0919 wrote:

>Hi Mark,

>

>Yes, it only happens when I run. It's gotten progressively worse over the

years. Three years ago I could run four hard miles and not have any issue. Now,

I have to keep it to three and I can't run very hard or I will definitely have a

reaction. I wear the clothing and shoes at other times, so it isn't that. It's

definitely exercise-induced anaphylaxis, as I've had two different allergists

diagnose it as that and I've done extensive research on it. I'm just wondering

if Xolair will help with this, as it helps with other allergies. I'm desperate

to talk to anyone else who suffers from this and compare notes. Maybe they know

of something that helps.

>

>Thank you for reading though and if you hear of anyone, will you please send

them my way?

>

>Thanks so much! :-)

>

>

>

>>

>> >Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

>> >

>> >When this happens to me at the gym, I immediately take two Benedryl, slow my

run to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

>> >

>> >I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

>> >

>> >My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

>> >

>> >I'm just looking for others who may have the exercise-induced anaphylaxis.

If so, has Xolair helped you with this?!

>> >

>> >Thank you for your time.

>> >

>> >

>> >

>> >

>> >------------------------------------

>> >

>> >

[Guest guest]

>

> Coop,

>

> Good luck. I have been taking Xolair shots for about 3 months now. It has been

miraculous for me with its affects.. I now get on the eliptical for 45 minutes

at a time, ski out west at 9000 feet and play tennis. All in all it has really

been a Godsend. I haven t started discussions with my doc about weening off my

asthma meds, but haven t had to take any steroids as in the past. I was

fortunate to have pretty fast results. Good luck

>

That's awesome to get results that fast. Some of us take up to and over a year

to see any results at all but when they come, its GREAT!

Doug

Group founder

On Xolair since Aug 2003

[Guest guest]

Has your doctor talked to you about the " lethal triad " ? Asthma, allergies and

nasal pollyps are indications of a lethal anaphylactic reaction to salicylates:

the substance found in aspirin and all non-steroidal anti-inflammatory drugs

(NSAIDS), like ibuprofen and Alleve.

The thing is that people have varying degrees of this sensitivity. Some are so

sensitive that any food containing any salicylate at all will set them off.

There are some really good lists on the web if you search on " salicylate

sensitivity " . Common foods with high content are mints, berries, and common

spices.

The good news is that, unlike food allergies, salicylate sensitivity is an IgE

response and is treated by Xolair. I have found that I can eat salicylate food

with little or no reaction, but I still avoid taking aspirin and other NSAIDS.

If you have had nasal pollyps, please ask your doctor about this possibility.

Regards,

Kitty

>

> Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

>

> When this happens to me at the gym, I immediately take two Benedryl, slow my

run to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

>

> I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

>

> My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

>

> I'm just looking for others who may have the exercise-induced anaphylaxis. If

so, has Xolair helped you with this?!

>

> Thank you for your time.

>

[Guest guest]

Interesting as I am very allergic to NSAIDS...

________________________________

From: Kitty <scruffy@...>

Sent: Tue, March 16, 2010 9:16:05 AM

Subject: [ ] Re: Exercise-induced anaphylaxis

Has your doctor talked to you about the " lethal triad " ? Asthma, allergies and

nasal pollyps are indications of a lethal anaphylactic reaction to salicylates:

the substance found in aspirin and all non-steroidal anti-inflammatory drugs

(NSAIDS), like ibuprofen and Alleve.

The thing is that people have varying degrees of this sensitivity. Some are so

sensitive that any food containing any salicylate at all will set them off.

There are some really good lists on the web if you search on " salicylate

sensitivity " . Common foods with high content are mints, berries, and common

spices.

The good news is that, unlike food allergies, salicylate sensitivity is an IgE

response and is treated by Xolair. I have found that I can eat salicylate food

with little or no reaction, but I still avoid taking aspirin and other NSAIDS.

If you have had nasal pollyps, please ask your doctor about this possibility.

Regards,

Kitty

>

> Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

>

> When this happens to me at the gym, I immediately take two Benedryl, slow my

run to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

>

> I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

>

> My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

>

> I'm just looking for others who may have the exercise-induced anaphylaxis. If

so, has Xolair helped you with this?!

>

> Thank you for your time.

>

[Guest guest]

Have you ever had an exercise study where this occurred in a controlled

environment?

________________________________

From: coop0919 <coop0919@...>

Sent: Mon, March 15, 2010 10:15:49 PM

Subject: [ ] Re: Exercise-induced anaphylaxis

Hi Mark,

Yes, it only happens when I run. It's gotten progressively worse over the years.

Three years ago I could run four hard miles and not have any issue. Now, I have

to keep it to three and I can't run very hard or I will definitely have a

reaction. I wear the clothing and shoes at other times, so it isn't that. It's

definitely exercise-induced anaphylaxis, as I've had two different allergists

diagnose it as that and I've done extensive research on it. I'm just wondering

if Xolair will help with this, as it helps with other allergies. I'm desperate

to talk to anyone else who suffers from this and compare notes. Maybe they know

of something that helps.

Thank you for reading though and if you hear of anyone, will you please send

them my way?

Thanks so much! :-)

>

> >Does anyone in this group suffer from exercise-induced anaphylaxis? I have

severe allergies and suffer from sinus infections (usually one every other

month), asthma, and exercise-induced anaphylaxis. I'm a runner and have to run

inside on the treadmill because of my allergies. I actually ran a 5K this

weekend and couldn't even go to work today because of my swollen eyes, runny

nose, and sneezing. Even when I run inside on the treadmill, I have to take

Xyzal at least half an hour before I go. Sometimes it works and I don't have a

reaction, but other times it doesn't. In the middle or near the end of a 30-40

minute run, I start experiencing tightness in my hands and begin breaking out

into hives all over my hands, arms, neck, and sometimes my legs/knees. This is

very scary for me because two years ago I had a reaction to a protein bar and

ended up in the emergency room (anaphylactic shock).

> >

> >When this happens to me at the gym, I immediately take two Benedryl, slow my

run to a walking cool-down, and then stop altogether. I've done all sorts of

" experiments " with the food I eat before I go, not eating at all, taking my

Xyzal at different time intervals, running slower vs. running hard, and the only

thing I see is that the harder I run, the more likely I am to experience this

phenomenon. I love to run, and am so nervous to exercise most of the time! I

have done some of the P90X workouts and I've never experience this with that

type of exercise.

> >

> >I have also had a major sinus surgery (in July 2008) to remove polyps and

correct a deviated septum. I was okay for about a year and then everything

started all over again. In October of 2009, my ENT told me that he wanted to do

another surgery. I told him that I was going to see a new allergist about other

options.

> >

> >My allergist recently sent me for blood work to start the process of getting

Xolair approved through my insurance company. I've been reading anything and

everything on this medication. I am nervous about starting this, but I feel like

it may be the only option for me. I was taking Advair, Singulair, Xyzal, and

Zyrtec DAILY, but my allergist took me off Advair and Zyrtec and replaced that

with Claritin-D. I have begun to cough again at night and have to use my inhaler

more often without the Advair. Not only is this expensive, it's exhausting!

> >

> >I'm just looking for others who may have the exercise-induced anaphylaxis. If

so, has Xolair helped you with this?!

> >

> >Thank you for your time.

> >

> >

> >

> >

> >----------- --------- --------- -------

> >

> >