Guest guest Posted May 10, 2011 Report Share Posted May 10, 2011 Hi , There is evidence that glutathione levels in primary colorectal cancers are significantly higher than in the corresponding normal tissues and, in addition, the high levels makes them more resistant to chemotherapy: http://www.ncbi.nlm.nih.gov/pubmed/10950013 HOWEVER, " Undenatured whey protein is one of the natural foods known to selectively deplete cancer cells of their glutathione, thus making them more susceptible to such cancer treatments as radiation and chemotherapy. " I'm sure Duncan would agree :-) http://www.emaxhealth.com/51/253.html Additional studies cited in the link above included the use of a novel prodrug (PABA/NO). " The glutathione-s-transferase in tumor cells converts PABA/NO to lethal nitric oxide, resulting in death of the tumor cell. The prodrug was shown to have antitumor effects in an animal model for human ovarian cancer. In the fourth study, Polish researchers found that ingesting a selenium supplement is beneficial, as a supportive element in chemotherapy. " I'm sure Duncan would agree with that one as well. Best, Dee >snip> > Duncan, someone in another group gave out an article that glutathione might not be good for cancer. Glutathion prevents cancer cells from dying. Do you know anything about this claim? > > Thanks. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 11, 2011 Report Share Posted May 11, 2011 Dee, Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > >snip> > > Duncan, someone in another group gave out an article that glutathione might not be good for cancer. Glutathion prevents cancer cells from dying. Do you know anything about this claim? > > > > Thanks. > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 11, 2011 Report Share Posted May 11, 2011 , I can't imagine that the glutathione in an avacado would be detrimental - especially since it contains other compounds that not only prevent but destroy cancer: http://www.healthdiaries.com/eatthis/10-health-benefits-of-avocados.html Prostate Cancer Prevention Avocados have been shown to inhibit the growth of prostate cancer. Oral Cancer Defense Research has shown that certain compounds in avocados are able to seek out pre-cancerous and cancerous oral cancer cells and destroy them without harming healthy cells. Breast Cancer Protection Avocado, like olive oil, is high in oleic acid, which has been shown to prevent breast cancer in numerous studies. In addition to their effect on cancer they have beneficial effects on eye health, cholesterol, heart health, and stroke prevention: Best, Dee > > Dee, > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 11, 2011 Report Share Posted May 11, 2011 Sorry, , but the glutathione in the avocado does nothing at all; oral glutathione is digested like meat. Even intravenous glutathione doesn't enter most cells. Dee's concerns have already been laid to rest; glutathione is a cancer treatment and potent preventive. all good, Duncan > > Dee, > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 11, 2011 Report Share Posted May 11, 2011 Oleic acid is also the main fat in butter, 25%-26% generally. The anti-cancer compounds in avocado would have to be concentrated to be effective. Calling the whole vegetable cancer-preventive because it contains miniscule amounts of an anti-cancer substance is unconscionable for a health zealot but typical of the marketing push that many people parrot. In this case there are 3 results for prostate avocado in PubMed. All three used extracts in a test tube. all good, Duncan > > > > Dee, > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 11, 2011 Report Share Posted May 11, 2011 Those were not MY concerns Duncan - they were 's. Perhaps you misunderstood my replies? The evidence I presented does not contradict your contention that glutathione is " a " cancer treatment. The fact remains, however, that elevated glutathione is a cause of resistance to anticancer agents and x-rays: http://www.ncbi.nlm.nih.gov/pubmed/10950013 Supplementing with glutathione in the form of undenatured whey, however, seems to have an opposite effect: http://www.emaxhealth.com/51/253.html Dee > > > > Dee, > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 11, 2011 Report Share Posted May 11, 2011 Marketing push? For Avocado's? Hmmm. I guess they'll be the next MLM then :-) But since when have you been opposed to test tube studies? I seem to remember how fast you held on to the notion that the lauric acid in coconut oil causes red blood cell hemolysis based on a 1973 test tube experiment with lauric acid - not coconut oil. At least the PubMed research on prostate/avocados actually used avocados (specifically Hass). And it wasn't Oleic acid that did the job: http://www.ncbi.nlm.nih.gov/pubmed/15629237 Dee > > > > > > Dee, > > > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2011 Report Share Posted May 12, 2011 Dee, when tissue glutathione is raised cancer cell glutathione DROPS; whey is patented as chemotherapeutic, and in conjunction with chemotherapy, much less chemo produces the same anticancer effect. Your short post that concerned was worded in a confusing way that portrayed glutathione as potentially bad. I'm just pointing out for her that it's quite the reverse. Glutathione is used to INCREASE the effectiveness of chemotherapy (an anticancer agent), and REDUCE the oxidative stress caused by x-rays. all good, Duncan > > > > > > Dee, > > > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2011 Report Share Posted May 12, 2011 Dee, I'm not opposed to test tube studies. I'm opposed to calling avocados a cancer therapy as you did, when clearly a potent extract thereof was used. all good, Duncan > > > > > > > > Dee, > > > > > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2011 Report Share Posted May 12, 2011 Duncan, I agree that whey is chemotherapeutic and said that in my post. Sorry you were confused by the first part. I find it intriguing that whey, which is a strong glutathione precursor is able to actually lower glutathione in the case of cancerous tissues in which the glutathione is higher than in normal tissue. Dee > > > > > > > > Dee, > > > > > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2011 Report Share Posted May 12, 2011 Just to set the record straight, Duncan, I did NOT say avacados are a cancer therapy. What I said was that it was a preventative - just as other fruits and vegetables that contain similar compounds are if consumed on a regular basis. The process of prevention also includes the ability to destroy cancerous cells when they are young and small before they have had a chance to develop into full blown cancer. I think most here would agree that a diet high in such items would be good preventative strategy. Further, the question was not about a cure for cancer but whether or not eating avacados would be detrimental. Dee > > > > > > > > > > Dee, > > > > > > > > > > Thanks for all the info. I've been eating avocado for breakfast for a number of years now with chia seeds, i wonder, if the glutathione in the avocado would be detrimental. > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 12, 2011 Report Share Posted May 12, 2011 My apologies to all for not trimming my last two posts! Will try to do better next time :-) Dee Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2011 Report Share Posted May 13, 2011 Many thanks Lew for the explanation. The fact it is performing a rebalancing act makes perfect sense, though I never cease to be amazed at the body's intelligence. Best, Dee > > < I find it intriguing that whey, which is a strong glutathione precursor > is able to actually lower glutathione in the case of cancerous tissues in > which the glutathione is higher than in normal tissue.> > > It is clear that high GSH levels protect cells, and low levels leave > them vulnerable. What is interesting to note, though, is that human cancer > cells generally have high GSH levels. Normally, glutathione levels are > tightly regulated by the cell, but in cancer, these levels are exceeded. > Again, something has gone terribly wrong here.Interestingly, when the > building blocks of glutathione are introduced into the system of a cancer > patient, it raises GSH in normal healthy cells but triggers the opposite > reaction in cancer cells, effectively shutting down their GSH production. > > This is known as* negative feedback inhibition*, and it is a > technical term meaning your healthy cells get stronger, and your cancer > cells get weaker. > > This enhances the effectiveness of the chemotherapy or radiation > treatment.At the same time, it reduces or eliminates side effects since your > healthy cells are not as vulnerable to damage. You are less damaged as a > result, and you feel much better than you would have without glutathione's > help > > Glutathione And Cancer - What Do I Need To Know To Protect My > Health? > > http://www.immune-health-solutions-for-you.com/glutathione-and-cancer.html > > > Enzymes whose ability to catalyze a reaction depends on molecules > other than the substances on which they act directly are said to be under > allosteric control.* Allosteric control* refers to a type of enzyme > regulation involving the binding of a non-substrate molecule, known as the > allosteric effector, at locations on the enzyme other than the active site. > The name " allo " means other and " steric " refers to a position in a certain > amount of space. In other words, allosteric means " at another place. " An > allosteric site is a site at which a small regulatory molecule interacts > with an enzyme to inhibit or activate that specific enzyme; which is > different from the active site where catalytic activity occurs. The binding > of the allosteric effector is in general noncovalent and reversible. This > interaction thus changes the shape of the enzyme which, in turn, changes the > shape of the active site. This change in conformation will either inhibit or > enhance the catalysis of a reaction. So the allosteric control allows the > cell to regulate the needed substances quickly through inhibition and or > enhancement. > > > With regards > Lew Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2011 Report Share Posted May 13, 2011 Your statement was unambiguous Dee: " Avocados have been shown to inhibit the growth of prostate cancer. " Not true. all good, Duncan > > Just to set the record straight, Duncan, I did NOT say avacados are a cancer therapy. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2011 Report Share Posted May 13, 2011 Saying " there's high glutathione in colon cancer cells " without explanation tends to mislead, thus is a disservice to readers including , who took it as a negative connotation that was actually unsupported by the research. I simply cautioned you to avoid that kind of ambiguity. I think " normal tissue " as you put it might have been normally low in glutathione, only for the reason that glutathione is somewhat depleted in the bowel lining due to the continual toxin assault, and often completely depleted in the lesion areas in bowel disease. Many MDs profess high bowel dysbiosis involvement in the population, my doctor says about 80%, so it's pretty hard to find a " healthy " or " normal " sample of people with no such involvement. Regardless of that study or how one uses its data, yes, the function of undenatured whey in reducing cancer has been researched and protected by a patent. all good, Duncan > > Duncan, > > I agree that whey is chemotherapeutic and said that in my post. Sorry you were confused by the first part. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2011 Report Share Posted May 13, 2011 Once again you appear to be AWFULLY sure of yourself Duncan. Any proof that the statement " inhibit the growth " is untrue? Dee > > Your statement was unambiguous Dee: " Avocados have been shown to inhibit the growth of prostate cancer. " > > Not true. > > all good, > > Duncan Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 13, 2011 Report Share Posted May 13, 2011 Yes, I agree that was mislead by my post as well. I apologize for that. However, your own response ignored the fact that colon cancer cells do indeed contain high glutathione. Dr. Lew, on the other hand, provided the explanation as to why this is true and the mechanism as to how supplementing with glutathione both raises glutathione in normal cells and lowers it in cancer cells. Dee > > Saying " there's high glutathione in colon cancer cells " without explanation tends to mislead, thus is a disservice to readers including , who took it as a negative connotation that was actually unsupported by the research. I simply cautioned you to avoid that kind of ambiguity. > Quote Link to comment Share on other sites More sharing options...
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