VCO, RBC hemolysis and oxidative stress

[Guest guest]

Hemolysis, whether from lauric acid or any other source, releases large amounts

of iron, a potent promoter of oxidative stress through a reaction that yields

hydroxyl radicals, the most damaging type of free radicals. This is the type

that causes the radiation sickness and accelerated aging in people who have

undergone radiation therapy.

If a person is taking coconut oil, extra antioxidants may be needed to quench

the hydroxyl ions. Glutathione is the main antioxidant of hydroxyl ions; the

precursor is in undenatured whey, which also contains ferritin, the purpose of

which besides delivering glutathione precursors is to bind free iron in the body

against this eventuality.

This study, " Hydroxyl radical is produced via the Fenton reaction in

submitochondrial particles under oxidative stress: implications for diseases

associated with iron accumulation " , points out, " The results indicate that

increased HO(*) levels occur in mitochondria under oxidative stress and that the

HO(*) levels can be modulated with antioxidant enzymes and iron ligands. "

><http://www.ncbi.nlm.nih.gov/pubmed/19490751>

Oxidative stress is a severe lifespan shortener through accelerated aging, and

iron has been linked to many oxidative stress disorders. Performing the search,

iron " oxidative stress " hydroxyl, in PubMed will retrieve 519 records.

In " Advances in metal-induced oxidative stress and human disease. "

><http://www.ncbi.nlm.nih.gov/pubmed/21414382>

" Disruption of metal ion homeostasis may lead to oxidative stress, a state where

increased formation of reactive oxygen species (ROS) overwhelms body antioxidant

protection and subsequently induces DNA damage, lipid peroxidation, protein

modification and other effects, all symptomatic for numerous diseases, involving

cancer, cardiovascular disease, diabetes, atherosclerosis, neurological

disorders (Alzheimer's disease, Parkinson's disease), chronic inflammation and

others. The underlying mechanism of action for all these metals involves

formation of the superoxide radical, hydroxyl radical (mainly via Fenton

reaction) and other ROS, finally producing mutagenic and carcinogenic

malondialdehyde (MDA), 4-hydroxynonenal (HNE) and other exocyclic DNA adducts.

On the other hand, the redox inactive metals, such as cadmium (Cd), arsenic (As)

and lead (Pb) show their toxic effects via bonding to sulphydryl groups of

proteins and depletion of glutathione. "

So, given that lauric acid lyses red blood cells as shown in the previous

research, one should also be taking glutathione precursors to quench the

oxidative stress, and the ligand (ferritin) to bind up any free iron. High

glutathione is an anti-aging tool anyway.

all good,

Duncan

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> The following study shows lauric acid breaks down (lyses) red blood cell walls

in normal blood salt (normotonic) conditions for blood of humans and two other

animals. Hemolysis may be the reason some people have symptoms from coconut oil

that are often attributed to the Herxheimer/Jarish effect (AKA healing

response); coocnut oil could be breaking down some of your red blood cells.

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