Guest guest Posted May 30, 2008 Report Share Posted May 30, 2008 - I posted this originally back in February. You really need to get a prescription from a doctor that understands . We were told to use a second dose only if the first dose didn't knock out the fever. Our daughter reacted highly to the Prednisone - became totally wild. So we had to use a very small dosage. Typically the fevers also come closer (ours came every 10-12 days) when we used the 2 mg/kg dosage. Ultimately, we determined that 4-7 day fevers every 20-30 days was too much to deal with and the Prednisone really affected her personality - so we opted for a T & A. While not for everyone, it has worked for us so far. We've now gone over 6 months without a fever. Hopefully the below information will help: Message 20426: I see a ton of posts that discuss doses of Prednisone in teaspoons. My concern when I read these is that it all depends on weight of your child (just like Motrin and Tylenol)... So I thought this might help some of you figure out the math and what dosage your doctors are recommending.... Please bear in mind that this is for a 15mg/5ml Orapred solution. Typical dosage recommendation is 1-2 mg/kg ---- note that a kg is about 2.2 pounds Also note that our Orapred dosage is 15mg/5mls (or 15 mgs per Teaspoon) To figure out pounds to kgs to figure out the dosage here's a calculation you can do: LB weight * .45 / 15 = Teaspoon for 1mg/kg Dosage OR LB weight * .45 / 3 = ML for 1mg/kg Dosage If your doctor is recommending 2mg/kg then you would double the result above. For example a 32 pound child is about 14.4 kgs. And at 15 mg/5 mls (our form of Orapred) - you would get 32x.45=14.44/15=.96 (or Roughly 1 teaspoon). We found that a .6mg/kg dose was about right for our daughter. She'd run a low 100 the day after, but didn't seem to impact her as much emotionally and the fevers spread out to about 25-35 days. Our daughter was 34 pounds and 3 mls worked for her (so that equates to about a .6mg dosage per kg) For those that get really confused with all the mls, kgs, mgs - especially when we use pounds in the US ---- I hope that the above helps you. BUT if for any reason you do it and the dosage seems WAY off... please check with a pharmacist or your doctor first. ----------------------------------------- ==================================================== This message contains PRIVILEGED and CONFIDENTIAL information that is intended only for use by the named recipient. If you are not the named recipient, any disclosure, dissemination, or action based on the contents of this message is prohibited. In such case please notify us and destroy and delete all copies of this transmission. Thank you. ==================================================== Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 3, 2008 Report Share Posted June 3, 2008 For our 5 year-old daughter, we give one dose (we're using the Orapred tablets, 15 mg dose) when we're sure that it's a fever episode and it starts spiking up. We give a second dose 24 hours later. We have found that the initial dose knocks the fever out and she's pretty much back to normal after a few hours, but if we don't give the second dose, the fever returns a day or so later and is then not very responsive to the prednasone. It works really well for her, except we're now trying to figure out if it's making her fevers come more frequently. It's not clear cut, since she's had longer spells right after a prednisone dose, and shorter spells without one (we haven't given it every single time). But overall, her fevers have increased to every three weeks on average for the past six months, so we don't know if it's connected to the prednasone or not. We're scheduling a T & A for this summer, because it's just too frequent now. Best wishes, Margie mom of 5 year-old Rowan with and 2 year-old Liam Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 3, 2008 Report Share Posted June 3, 2008 For our 5 year-old daughter, we give one dose (we're using the Orapred tablets, 15 mg dose) when we're sure that it's a fever episode and it starts spiking up. We give a second dose 24 hours later. We have found that the initial dose knocks the fever out and she's pretty much back to normal after a few hours, but if we don't give the second dose, the fever returns a day or so later and is then not very responsive to the prednasone. It works really well for her, except we're now trying to figure out if it's making her fevers come more frequently. It's not clear cut, since she's had longer spells right after a prednisone dose, and shorter spells without one (we haven't given it every single time). But overall, her fevers have increased to every three weeks on average for the past six months, so we don't know if it's connected to the prednasone or not. We're scheduling a T & A for this summer, because it's just too frequent now. Best wishes, Margie mom of 5 year-old Rowan with and 2 year-old Liam Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 3, 2008 Report Share Posted June 3, 2008 For our 5 year-old daughter, we give one dose (we're using the Orapred tablets, 15 mg dose) when we're sure that it's a fever episode and it starts spiking up. We give a second dose 24 hours later. We have found that the initial dose knocks the fever out and she's pretty much back to normal after a few hours, but if we don't give the second dose, the fever returns a day or so later and is then not very responsive to the prednasone. It works really well for her, except we're now trying to figure out if it's making her fevers come more frequently. It's not clear cut, since she's had longer spells right after a prednisone dose, and shorter spells without one (we haven't given it every single time). But overall, her fevers have increased to every three weeks on average for the past six months, so we don't know if it's connected to the prednasone or not. We're scheduling a T & A for this summer, because it's just too frequent now. Best wishes, Margie mom of 5 year-old Rowan with and 2 year-old Liam Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 4, 2008 Report Share Posted June 4, 2008 Hello, I just joined this group today, so glad to have found it. My 4 1/2 was diagnosed a year ago with . We started prednisone last year and now we are using orapred, same dosage as you. I have noticed that the episodes have increased. Yes, the orapred takes away the symptoms within a few hours, however the fever will be back within 4-5 days (our typical cycle is every 2 weeks). Our doctor recommeneded giving the second dose 24 hours later, he said steriod treatment can increase the episodes, I never had this on prednisone although they say orapred is the same thing. We tried it this way once and found we gained 2 more days in between. I am so confused because I don't think steriods are a " great " thing to be on. We did have two weeks in between episodes the last time and we only did the orapred once. We had an episode yesterday, gave him the orapred so anxious to see how long we get until the next time. Are you having the tonsils removed? Curious to see your opinion on that I keep reading conflicting info. Take Care! Jackie, Landon's mom Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 4, 2008 Report Share Posted June 4, 2008 Hello, I just joined this group today, so glad to have found it. My 4 1/2 was diagnosed a year ago with . We started prednisone last year and now we are using orapred, same dosage as you. I have noticed that the episodes have increased. Yes, the orapred takes away the symptoms within a few hours, however the fever will be back within 4-5 days (our typical cycle is every 2 weeks). Our doctor recommeneded giving the second dose 24 hours later, he said steriod treatment can increase the episodes, I never had this on prednisone although they say orapred is the same thing. We tried it this way once and found we gained 2 more days in between. I am so confused because I don't think steriods are a " great " thing to be on. We did have two weeks in between episodes the last time and we only did the orapred once. We had an episode yesterday, gave him the orapred so anxious to see how long we get until the next time. Are you having the tonsils removed? Curious to see your opinion on that I keep reading conflicting info. Take Care! Jackie, Landon's mom Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 4, 2008 Report Share Posted June 4, 2008 Hello, I just joined this group today, so glad to have found it. My 4 1/2 was diagnosed a year ago with . We started prednisone last year and now we are using orapred, same dosage as you. I have noticed that the episodes have increased. Yes, the orapred takes away the symptoms within a few hours, however the fever will be back within 4-5 days (our typical cycle is every 2 weeks). Our doctor recommeneded giving the second dose 24 hours later, he said steriod treatment can increase the episodes, I never had this on prednisone although they say orapred is the same thing. We tried it this way once and found we gained 2 more days in between. I am so confused because I don't think steriods are a " great " thing to be on. We did have two weeks in between episodes the last time and we only did the orapred once. We had an episode yesterday, gave him the orapred so anxious to see how long we get until the next time. Are you having the tonsils removed? Curious to see your opinion on that I keep reading conflicting info. Take Care! Jackie, Landon's mom Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 5, 2008 Report Share Posted June 5, 2008 Hi - Welcome, I know you will find this site useful as well as therapeutic. I have found that if I give the orapred too soon the fever comes back in a few days so I wait until the fever is about 102 then give it to my daughter. I know info. was posted on this awhile back on this site. Hope this helps. Lynn ] Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 5, 2008 Report Share Posted June 5, 2008 Thank you Lynn! I noticed during the last episode I did give the orapred a day after it started and we did get a longer period of time in between episodes. Take Care. Jackie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 5, 2008 Report Share Posted June 5, 2008 Thank you Lynn! I noticed during the last episode I did give the orapred a day after it started and we did get a longer period of time in between episodes. Take Care. Jackie Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 Hi Frances Is that fluid, protein or fats you are loosing? Methotrexate is an antimetabolite...may impede protein (muscle) repair unless the catabolic effect is a desired outcome. I wonder if you've activated the adipocytes into releasing some of the fats, then burning them off? best wishes Bob > Hi All > I expect this seems an odd question but here goes anyway. I have been > hypothyroid for many years and take 5 grains of Armour Thyroid. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 Thanks for that Bob. You may well be right. It will be interesting to see if the weight loss continues. At least my Arthritis seems a little better! Regards Frances > > Hi All > > I expect this seems an odd question but here goes anyway. I have been > > hypothyroid for many years and take 5 grains of Armour Thyroid. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 > > Recently I have been diagnosed with Psoriaic Arthritis and been put on > Methaltrexate (175 mg) and Prednisolone.(20mg).I have now been taking > > > What I wondered is does prednisolone work on the adrenals. Could this > have made my Armour work better and therefore caused the weight loss Hi I will bow to Bob's greater knowledge, but certainly prednisilone is used for adrenal support (in smaller doses) and so it may have helped the armour be used better. It is the same stype of steroid as hydrocortisone but is much longer acting. Either way, I'm glad it's helping you. Leah x Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 Hi Frances Yes, Prednisolone is used in adrenal insufficiency, and the fact that you have been taking it and suddenly started to lose weight is because you obviously had low adrenal reserve and your body was unable to absorb all the thyroid hormone you were taking, so quite simply, it wasn't doing the job it should. Once people get their adrenals boosted, they often find they do not need as much thyroid as they were taking before. Obviously, your metabolism has started to speed up, so you will lose the weight. You really should have been told to stop your thyroid hormone when you started taking Prenisolone and then start your Armour again at a reduced rate and build it up again after a couple of weeks. Also, 20 mg Prednisolone seems a large dose. You can take either Hydrocortisone - Prednisolone - Methyprednisolone or Dexamethasone to boost your adrenals. You hit on the right medication obviously. Luv - Sheila What I wondered is does prednisolone work on the adrenals. Could thishave made my Armour work better and therefore caused the weight lossor could I have retained a lot of fluid and something is acting like adiuretic.The pain is getting better so I know the methaltrexate iskicking in at last and causing some of the swelling to go down but itseems such a fortuitous side effect. Regards FrancesNo virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.10/1638 - Release Date: 27/08/2008 19:06 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 Hi Frances, [[...For psoriasis, the starting oral dose is a single 7.5 mg dose weekly or 2.5 mg every 12 hours for three doses, once weekly....]] http://www.medicinenet.com/methotrexate/article.htm Was there a mix-up over this number on you post? best wishes Bob >> Hi All> > I expect this seems an odd question but here goes anyway. I have been Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 Hi Bob The dose of metheltrexate is what the rhumatoligist prescribed and I have not had much problem with side affects so i can only suppose it is OK. My GP was quite happy with it too.I started with 6x2.5mg once a week for three weeks now I am on 7x2.5 per week for three weeks and then I go up to 8x2.5 mg and stay on that until I see her again.Don't forget this is for psoriaic arthritis. Many thanks Frances > > > > Hi All > > > > I expect this seems an odd question but here goes anyway. I have been > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2008 Report Share Posted August 28, 2008 Sorry Frances, I couldn't see the decimal point; shown as 175mg (missing?) Bob > > Hi Bob > The dose of metheltrexate is what the rhumatoligist prescribed and I Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 29, 2008 Report Share Posted August 29, 2008 ....and doesn't that decimal point make a massive difference ?? Luv - Sheila Methaltrexate (175 mg) and Prednisolone.(20mg).I have now been taking the decimal point is missing....lol Bob .. No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.10/1638 - Release Date: 27/08/2008 19:06 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 10, 2009 Report Share Posted March 10, 2009 We had the same problem and had to stop using it because of behavior issues on the medicine. I have heard that for some people if you continue to use it they will space back out. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 10, 2009 Report Share Posted March 10, 2009 My sons fever will go away for a day and then return the next and when he takes it he cycles every two weeks instead of every 28 days.If he doesnt use it his fevers will go as high as 106 We really have no choice but to take it .He will go next month to have a T & A we are hoping this will work. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 10, 2009 Report Share Posted March 10, 2009 I was told by our doctor if the fever does not go away with the first dose that we can give a second 12 hours later. Have any of you heard this? Klara is newly diagnosed and has been having fevers for a year but only had predisone once. I have a feeling another fever is coming soon though and Bouman 29:11 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 11, 2009 Report Share Posted March 11, 2009 That is the EXACT same scenario we had with the first dose. Teagan gets only swollen glands and her head hurts. Hers came back about 18 hrs after dose. The next cycle it worked like a charm! Stacey Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 11, 2009 Report Share Posted March 11, 2009 Our doctor advised the same thing. We only had it not work the first time and we opted not to give her a second dose. I don't like how wired it makes her so I doubt that we would ever go for the second dose Stacey Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2009 Report Share Posted October 6, 2009 Chip is 6, about 40 lbs. He takes 13.3 ml the first day and 6.6 ml the 2nd day. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 6, 2009 Report Share Posted October 6, 2009 Prednisolone and prednisone dosages are based on the child's weight (and sometimes are adjusted depending on how the child responds to the medication), so not all 5 year-olds would get the same dose. Hope that helps- Kathy (Pediatric RN) mom of Josh (TRAPS / ) Quote Link to comment Share on other sites More sharing options...
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