Another Question

November 13, 2006

It is not used for treatment of hepatitis c , they use it on infants to treat RSV

Re: Re: Another Question

Never heard of it! Liz??? <marvindamartian05 > wrote:

Hey, there is something called Virazole, which it says is an inhalantversion of Ribavarin. anyone have any experience with this?> > >> > > PegIntron/RBV Effective for >65 Year Olds> > > > > > Reported by Jules Levin> > > AASLD, Oct 27-31, 2006, Boston, MA> > > > > > â?oPegylated Interferon alfa-2b + Ribavirin Is Equally > Efficacious > > > and Well Tolerated in Patients >65 Years Old in Comparison to > Other > > > Age Groups: Subanalysis of a Randomized, Controlled Study > (WIN-R > > > Trial)â?> > > > > > S. L. Flamm,1 I. M. son,2 R. S. Brown,3 B. Freilich,4 N. > > > Afdhal,5 P. Kwo,6 J. Santoro,7 S. Becker,8 A. Wakil,9 D. > Pound,10 J. > > > Harvey,11 L. H. Griffel,11 C. A. Brass11> > > 1Northwestern University, Chicago, Illinois; 2Weill Medical > College > > > of Cornell University, New York, New York; 3Columbia > University > > > College of Medicine, New York, New York; 4Baptist Medical > Center, > > > Kansas City, Missouri;> > > 5Beth Israel Deaconness Medical Center, Boston, > Massachusetts; > > > 6Indiana University School of Medicine, Indianapolis, > Indiana; > > > 7Atlantic Gastroenterology, Egg Harbor Township, New Jersey; > 8Austin > > > Gastroenterology, PA, Austin, Texas;> > > 9California Pacific Medical Center, San Francisco, > California; > > > 10Indianapolis Gastroenterology, RSCH, Indianapolis, Indiana; > > > 11Schering-Plough Research Institute, Kenilworth, New Jersey> > > > > > AUTHOR CONCLUSIONS> > > Patients 18 to 25 years of age had the highest SVR rate (57%) > among > > > the 6 age groups.> > > > > > The SVR rate in patients older than 65 years (46%) was > similar to the > > > SVR rates observed in younger age groups (41%-57%).> > > > > > Although elderly patients tended to experience more AEs, the > rate of > > > SAEs was similar in all groups, and the incidence of > treatment > > > discontinuation in elderly patients was similar to or less > than that > > > of younger patients.> > > > > > Data from this subanalysis of the WIN-R trial strongly > suggest that > > > patients should not be denied antiviral therapy based on age > alone.> > > > > > > > > Abstract*> > > Background: Peg interferon (IFN) + ribavirin are the standard > of care > > > for chronic HCV. There is reluctance to administer anti-viral > > > medications to older populations due to a fear of side > effects and > > > possible decreased efficacy. Limited data is available on > pts. age > > > >65 due to ineligibility for clinical trials. The role of age > in > > > determining response to IFN-based antiviral therapy for > chronic HCV > > > has not been clearly defined.> > > > > > Aim: To determine if age is an independent predictor of > sustained > > > virological response (SVR) or medication tolerability within > a > > > randomized, controlled clinical trial of treatment-naive pts. > with > > > HCV. Patient age grps studied: 18-25 yrs., n=69; 26-35 yrs., > n=350; > > > 36-45 yrs., n=1866; 46-55 yrs., n=2200; 56-65 yrs., n=368; > and >65 > > > yrs., n=55.> > > > > > Methods: A retrospective review of the multi-center WIN-R > trial > > > database was undertaken. Pts. were randomized to receive PEG > IFN 2b > > > (1.5 g/kg/wk) + either ribavirin 800 mg/d or ribavirin 800mg-> 1400 > > > mg/d based on body wt. Pts. with HCV GT1/4 received 48 wks of > therapy > > > while pts with HCV GT 2/3 were randomized to 24 or 48 wks of > therapy. > > > 4913 pts. received at least 1 dose of medication and are > included in > > > this analysis. Although pts. age >65 yrs. were ineligible, 55 > such > > > pts. Were enrolled as protocol exceptions. Logistic > regression > > > analyses of SVR comparing two age categories were performed. > The > > > potential influence of demographic variables on SVR was > evaluated > > > using the chi square test (two-way frequency table).> > > > > > Results: > > > The overall SVR was 44%. > > > > > > SVR rates for the grps were: > > > 18-25 yrs. = 57%, > > > 26-35 yrs. = 41% (p=0.02 vs 18-25),> > > 36-45 yrs. = 44% (p=0.03 vs 18-25), > > > 46-55 yrs. = 42%, > > > 56-65 yrs. = 40% (p=0.01 vs 18-25) and for > > > >65 yrs. SVR = 45%.> > > > > > There was no difference in SVR in any other pt. age grps > including > > > pts. age >65 yrs. > > > > > > There were no differences in SAEs between all age groups. > Pts. age 26-> > > 35 yrs., 36-45 yrs. and 46-55 yrs. had fewer AEs than those > in the 56-> > > 65 yrs. and the >65 yrs. age groups. > > > > > > Treatment discontinuations were significantly higher among > the 26-35 > > > yrs. group when compared to two groups but there was no > difference in > > > the treatment discontinuations in the >65 yrs. group compared > with > > > any other.> > > > > > Conclusions: > > > 1) Adults age 18-25 yrs. had significantly increased chances > of > > > obtaining SVR than most other age groups.> > > 2) Pts. >65 had similar SVR to all other age groups. > > > 3) Although there were more AEs in the older age groups, the > rate of > > > SAEs was the same and treatment drop-outs were the same or > less than > > > the younger age groups. > > > 4) Pts. should not be denied anti-viral therapy based upon > age alone.> > > > > > *Poster presents data updated since abstract submission.> > > > > > > > > The Weight-Based Dosing of Peginterferon alfa-2b and > Ribavirin (WIN-> > > R) study was a prospective, multicenter, community and > academic-> > > based, open-label, investigator-initiated, US clinical trial > that > > > evaluated the efficacy and safety of PEG-IFN alfa-2b plus > flat-dose > > > or weight-based ribavirin in treatment-naive patients with > chronic > > > hepatitis C.> > > - Overall SVR rates were 44% in the weight-based ribavirin > arm and > > > 41% in the flat-dose ribavirin arm (P = .020).3> > > - SVR rates in patients with chronic hepatitis C caused by > hepatitis > > > C virus (HCV) genotype 1 (G1) were 34% and 29%, respectively > (P > > > =.004).3> > > - Weight-based ribavirin dosing was associated with higher > rates of > > > dose reduction for anemia but not with higher rates of > > > discontinuation.3> > >> > > > > > > > > > > > > > ----------------------------------------------------------> ----------> > Everyone is raving about the all-new beta.> >> > > > > > > ---------------------------------> Everyone is raving about the all-new beta.>Jackie

January 24, 2007

Kathie,

I was out when they

inserted my pacemaker and six months later when they took it out and put in an

ICD. I am also getting older and

more forgetful with every day.

Having said that I

think they sometimes have to do a lot of pushing and tugging of various parts

of our chest and arms to get the ICD and wires into place. My memory says that it takes awhile for

all the aches and pains to go away.

You should have

gotten some instructions when you left the hospital for warning signs of

infection and the like. If you

suspect there is something wrong I would call the doctor’s office ASAP. If you just want the aches and pains to

go away quicker I would wait and talk to them.

I had open heart 15

years ago to replace a heart valve and after that a cough could make me see

stars in the middle of the day.

The ICD was a piece of cake compared to that but I am not going to lie

and say it didn’t hurt. The good

news is that for most folks the aches and pains go away and we can’t remember

them.

Maybe knitting isn’t

enough of a distraction. Maybe you

should write an article on what is normal. That would take some serious thinking.

Good luck!

Joe Schmidt – Don’t

you dare call me normal.

God Loves Us All

-----Original

Message-----

From:

[mailto: ]On Behalf Of Kkiefer440@...

Sent: Wednesday, January 24, 2007

10:08 AM

Subject: Another

Question

Good

morning. I have and still have pain when I take a breath in the middle

upper part of my chest. Has anyone experienced this? I have an

app for Friday at the Pacer Clinic for the wound site inspection, then on the

30th to see the Heart Dr or Pa. I can ask questions then but Of course

you all have gone through this first hand so would know what I am talking

about and if it is normal.

Thanks,

Kathie

kathiesknittingkwips

January 24, 2007

> Good morning. I have and still have pain when I take a breath in the

> middle upper part of my chest. Has anyone experienced this? I have

> an app for Friday at the Pacer Clinic for the wound site inspection,

> then on the 30th to see the Heart Dr or Pa. I can ask questions then

> but Of course you all have gone through this first hand so would know

> what I am talking about and if it is normal.

Kathie, I'm 8 months out from mine and it still hurts. Sometimes just a

bit, and sometimes a lot, but it's always achey. I'm hoping this will

subside with time--indeed, it's much better than it was at first, and

gets better all the time, but it's slow and annoying.

Lynn S.

------

Mama, homeschooler, writer, activist, spinner & knitter

http://www.siprelle.com

NOTICE: The National Security Agency may have read this email without

warning, warrant, or notice.

January 26, 2007

----- Original Message -----

From: " Lynn Siprelle "

> I have and still have pain

> when I take a breath in the

> middle upper part of my

> chest. Has anyone

> experienced this?

%%% Yes. When I don't do my housework, my wife hits me with the vacuum

cleaner wand. (Did you know that there is a mace attachemet just for lazy

husbands?)

From California where of all the household chores to be done, my favorite is

catching dust before it falls on the recliner. Of course it takes my whole

body to prevent the recliner from getting dusty, but I am a professional.

Bill

July 28, 2007

PDD is the umbrella term for language and communication disorders. Under this

umbrella you have autism, PDD-NOS (not otherwise specified) meaning not sure how

to diagnose exactly, but their is a problem, rhett's disorder, autism and

aspergers. In the DSM-IV ( diagnostic manuals psychology) all this information

is found. Children diagnosed with aspergers ususally have a very good language

and communication base, but are very literal, have difficulty with social skills

due to inability to read body language and facial expressions appropriately.

There are several excellent books to explain all this. Kids can aslo have dual

diagnosis such as ADD/ADHD and OCD, just to name a few. I hope this has been

helpful and feel free to email me with questions. I will double check my DSM to

make sure my info is correct. Aspergers was added to the DSM later, so some

people do not consider it " autism " , but rather on the spectrum.

Lesli

Sent via BlackBerry from T-Mobile

Another question

Thanks to the people that replied to me about the other question.

This is another question

In the Ian project they have this list

If you notice they mentiion ASD, then Autism, then Autistic disorder... are

they all the

same, or what are the differences?

Also in he PDD is mentioned 1rst PDD alone then PDD-Nos ( what is the

difference)

I mean this make things very confusing when they diagnose your children , why

do they

always make it sound like PDD is a different disorder.

I hope someone can help, cause to new parents this can be very confusing.

We have being living with autism since 2004

And with 3 boy's diagnosed from classic autism to severe autistic.

And this question is because sometimes even myself gets a little confused about

this.

Autism Spectrum Disorder (ASD)

Autism

Asperger Syndrome

Autistic Disorder

Pervasive Developmental Disorder (PDD)

Pervasive Developmental Disorder-Not Otherwise Specified (PDD-NOS)

Childhood Disintegrative Disorder (CDD)

***UPDATE*****

For those who are so kind to ask.. we have hired and attorney pn education law

at this

time to help us out... lets see how that goes, wish my 3 little guys good luck!

We are looking in to getting what our children deserve .

Messages in this topic

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/message/45089;_ylc=X3oDMTM1\

MG1vNG40BF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEbXNnSWQDNDUw\

ODkEc2VjA2Z0cgRzbGsDdnRwYwRzdGltZQMxMTg1NjQ4OTk0BHRwY0lkAzQ1MDg5> (1)

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/post;_ylc=X3oDMTJwdmQydGFlB\

F9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEbXNnSWQDNDUwODkEc2VjA\

2Z0cgRzbGsDcnBseQRzdGltZQMxMTg1NjQ4OTk0?act=reply & messageNum=45089> Reply (via

web post) |

Start a new topic

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/post;_ylc=X3oDMTJkZ2hwZHJ0B\

F9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDbnRwY\

wRzdGltZQMxMTg1NjQ4OTk0>

Messages

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/messages;_ylc=X3oDMTJkajRvd\

jljBF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDb\

XNncwRzdGltZQMxMTg1NjQ4OTk0> | Files

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/files;_ylc=X3oDMTJlNDNxM2Zr\

BF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDZmls\

ZXMEc3RpbWUDMTE4NTY0ODk5NA--> | Photos

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/photos;_ylc=X3oDMTJkMWR1MDV\

kBF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDcGh\

vdARzdGltZQMxMTg1NjQ4OTk0> | Links

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/links;_ylc=X3oDMTJlcWMzbjc4\

BF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDbGlu\

a3MEc3RpbWUDMTE4NTY0ODk5NA--> | Database

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/database;_ylc=X3oDMTJiaDc0Z\

DlwBF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDZ\

GIEc3RpbWUDMTE4NTY0ODk5NA--> | Polls

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/polls;_ylc=X3oDMTJldmtlOW5i\

BF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDcG9s\

bHMEc3RpbWUDMTE4NTY0ODk5NA--> | Members

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/members;_ylc=X3oDMTJkZXJodj\

JvBF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDbW\

JycwRzdGltZQMxMTg1NjQ4OTk0> | Calendar

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/calendar;_ylc=X3oDMTJjMzZjZ\

DRsBF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDY\

2FsBHN0aW1lAzExODU2NDg5OTQ->

Texas Autism Advocacy

www.TexasAutismAdvocacy.org

Texas Disability Network

Calendar of Events

www.TexasAutismAdvocacy.org

<http://groups.yahoo.com/;_ylc=X3oDMTJjaWpkcWN1BF9TAzk3MzU5NzE0BGdycElkAzI0NTE4M\

gRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDZ2ZwBHN0aW1lAzExODU2NDg5OTQ->

Change settings via the Web

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/join;_ylc=X3oDMTJlMTJxMWg0B\

F9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDc3RuZ\

3MEc3RpbWUDMTE4NTY0ODk5NA--> (Yahoo! ID required)

Change settings via email: Switch delivery to Daily Digest

<mailto:Texas-Autism-Advocacy-digest ?subject=Email Delivery:

Digest> | Switch format to Traditional

<mailto:Texas-Autism-Advocacy-traditional ?subject=Change

Delivery Format: Traditional>

Visit Your Group

<http://groups.yahoo.com/group/Texas-Autism-Advocacy;_ylc=X3oDMTJjaTNoN2liBF9TAz\

k3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA2Z0cgRzbGsDaHBmBHN0aW\

1lAzExODU2NDg5OTQ-> |

Yahoo! Groups Terms of Use <http://docs.yahoo.com/info/terms/> |

Unsubscribe

<mailto:Texas-Autism-Advocacy-unsubscribe ?subject=>

Recent Activity

*

7

New Members

<http://groups.yahoo.com/group/Texas-Autism-Advocacy/members;_ylc=X3oDMTJlNHVwYz\

AwBF9TAzk3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA3Z0bARzbGsDdm\

1icnMEc3RpbWUDMTE4NTY0ODk5NA-->

Visit Your Group

<http://groups.yahoo.com/group/Texas-Autism-Advocacy;_ylc=X3oDMTJkZWhoa3FvBF9TAz\

k3MzU5NzE0BGdycElkAzI0NTE4MgRncnBzcElkAzE3MDUwNjE2MTYEc2VjA3Z0bARzbGsDdmdocARzdG\

ltZQMxMTg1NjQ4OTk0>

July 28, 2007