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RE: CoQ10-suzi

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The one I use is way more expensive than

this – but instead of the soybean oil in it, it is emulsified in organic

flaxseed oil (good source of Omega3’s)

and it’s also blended with a couple different nutritional algaes (also good

as antioxidants). I wonder if that

could be the difference in price. It’s probably more potent. I pay $33 for 60 caps.

Carol

-----Original

Message-----

From: Suzanne

[mailto:suziesgoats@...] Here is what I get.....

Suzi CoQ10, Coenzyme Q10

Each capsule 60mg

60 Caps - $18.19

120 Caps - $34.96

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The one I buy is a form called " Q-Gel " . It's alleged (by studies) to

be the most bioavailable form of CoQ10. It has a unique ability

however. Once it's in your body and taken for 7 days, it triples in

potency. Thus a 60mg softgel gives you the equivalency of 180mg

after the 7 days. For a 60 softgel/60mg bottle it runs $23.09. The

company that makes this is at: http://www.tishcon.com/

On 23 Jul 2004 at 5:09, Suzanne wrote:

> Here is what I get..... Suzi

> CoQ10, Coenzyme Q10

> Each capsule 60mg

> 60 Caps - $18.19

> 120 Caps - $34.96

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Suzi,

Here's what I based what I said on. From personal experience, in taking their 100mg s/g versus capsulized powdered and normal softgels, their product is VERY superior in terms of my energy levels when taking it.

Now if my income allowed to continue that level. (grin)

There's more below. Check out the site's info.

Skip

----------------------------------------------------------------------------

Much more info: http://tishcon.com/coqgel.html

Graphs here: http://www.tishcon.com/graphs.html'>http://www.tishcon.com/graphs.html

This is from: http://tishcon.com/disabstract.html

Dissolution and Relative Bioavailability of CoEnzyme Q10

Abstract:

Most Coenzyme Q10 dosage forms exhibit negligible dissolution indicating potentially poor bioavailability. In order to improve its dissolution profile and thereby its absorption, a new process (Bio-Solv ®) was employed to produce Q-Gel ® Softsules. This novel formulation in the form of a softgelatin capsule passes the USP Dissolution requirement for nutritional supplements. When compared with other commercially available dosage forms for relative bioavailability in human subjects, Q-Gel ® was found to be vastly superior (a 6 fold increase in plasma CoQ10 values over baseline, and several fold greater relative bioavailability over other dosage forms tested).

Coenzyme Q10 (Ubiquinone) is a lipid-soluble compound found in the mitochondria of all living cells. It also occurs in the food chain and is endogenously produced in the liver. There are conditions in which adequate production of CoQlO in the body is impaired, and in such situations supplementation with CoQ10 has been shown to be very beneficial.

CoQlO, being lipid soluble, follows the same pathway as that of fats for its absorption in the body. This involves emulsification in the intestine (with the help of bile salts) and the formation of micelles prior to absorption. Among the other factors affecting the absorption of exogenously administered CoQlO are its particle size, degree of solubilization, and the type of food ingested with the supplement.

Although CoQlO is classified as a lipid soluble substance, its degree of solubility is extremely limited. Commercially available CoQlO capsules contain either oil-based suspensions (softgels), or dry powder blends (hard gels). When tested in the laboratory, these products show a total lack of dissolution according to current USP methodology. Such lack of dissolution properties are often indicative of poor absorption and bioavailability.

In order to improve the dissolution profile and bioavailability of CoQl0, Tishcon Corp. has acquired an exclusive technology/process from BioSytes, USA, Inc. This novel Bio-Solv® process has provided the key to the solubilization of CoQlO. Q-Gel® softsules® based on the Bio-Solv® process exhibit optimum dissolution, which is indicative of improved absorption/bioavailability.

Several human studies have been subsequently carried out to compare the relative bioavailability of Q-Gel® with other currently available dosage forms (softgels, tablets and capsules), and the data obtained from these studies clearly demonstrate that Q-Gel® is vastly superior (several times higher relative bioavailability than all other dosage forms tested).

These data were presented at the Annual Meeting of the American Society for Nutritional Sciences/Experimental Biology in New Orleans on April 9, 1997.

(Chopra, R., Goldman, R., Bhagavan, H.N., A new Coenzyme Q10 preparation with enhanced relative Bioavailability).

On 23 Jul 2004 at 10:33, Suzanne wrote:

>

> Now how does that work? I always thought your body discarded what it didn't need in the vitamin

> area... Never heard of one doing this.

> Suzi

>

> Skip <res08wix@...> wrote:

> The one I buy is a form called " Q-Gel " . It's alleged (by studies) to

> be the most bioavailable form of CoQ10. It has a unique ability

> however. Once it's in your body and taken for 7 days, it triples in

> potency. Thus a 60mg softgel gives you the equivalency of 180mg

> after the 7 days. For a 60 softgel/60mg bottle it runs $23.09. The

> company that makes this is at: http://www.tishcon.com/

>

>

> On 23 Jul 2004 at 5:09, Suzanne wrote:

>

> > Here is what I get..... Suzi

> > CoQ10, Coenzyme Q10

> > Each capsule 60mg

> > 60 Caps - $18.19

> > 120 Caps - $34.96

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Co Q 10 that I use - http://tinyurl.com/f1f7

-----Original

Message-----

From: Suzanne

[mailto:suziesgoats@...]

probably so. where

do you get yours or what is brand name?

Suzi

Carol Minnick

<carolminnick@...> wrote:

The one I use is way more

expensive than this – but instead of the soybean oil in it, it is

emulsified in organic flaxseed oil (good source of Omega3’s)

and it’s also blended with a couple

different nutritional algaes

(also good as antioxidants). I wonder if that could be the difference

in price. It’s probably more potent.

I pay $33 for 60 caps.

Carol

-----Original

Message-----

From: Suzanne

[mailto:suziesgoats@...] Here is what I get..... Suzi CoQ10, Coenzyme Q10

Each capsule 60mg

60 Caps - $18.19

120 Caps - $34.96

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Depends on what size. The 60mg/60qty is about $23.09 a bottle.

The 100mg/60qty is about $32.99 a bottle. That pricing is at

Swanson btw. Their site seems down for some reason so I can't

get actual pricing right now.

Skip

On 23 Jul 2004 at 16:48, Suzanne wrote:

> Ok Skip... now I get it.. thanks.

> So how much is this?

> Suzi

>

> Skip <res08wix@...> wrote:

> I arrived at that statement as follows:

>

> 1) " When compared with other commercially available dosage forms for relative

> bioavailability in human subjects, Q-Gel ® was found to be vastly superior (a

6 fold

> increase in plasma CoQ10 values over baseline, and several fold greater

relative

> bioavailability over other dosage forms tested). " From:

http://tishcon.com/disabstract.html

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Yes I do take their brand and always the Q-Gel's. I've had good

luck with all of the Swanson house brand products that I've used.

They all seem to be really good quality. Another good thing is flat

rate shipping of ... I think it's $4.95 and they are FAST. Place the

order online and usually they are picking it before you can call

them on the phone! I found this out a couple of times when I

needed to add on to my order. Fast they are! :)

Skip

On 23 Jul 2004 at 22:05, Pee Tee wrote:

> Do you take this brand Skip?

> Looks like the one to spend money on. Is this the concensus ?

> When is the optimal time of day to take this stuff ?

> Pam

> -------------------------------------------------------------------------

> I arrived at that statement as follows:

>

> 1) " When compared with other commercially available dosage forms for

> relative bioavailability in human subjects, Q-Gel ® was found to be vastly

> superior (a 6 fold increase in plasma CoQ10 values over baseline, and

> several fold greater relative bioavailability over other dosage forms

> tested). "

> From: http://tishcon.com/disabstract.html

>

> _________________________________________________________________

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>

>

>

>

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