Guest guest Posted October 15, 2011 Report Share Posted October 15, 2011 L-arginine and l-lysine alone or together did not increase HGH very much in the research and l-arginine competes for uptake with l-lysine. Because arginine pyroglutamate does not compete for the same pathway lysine is complementary and synergistic with it; 1:1 1200 mg of each was used in the Isidori study. I compared arginine pyroglutamate to arginine alpha-ketoglutarate and it seems the ketoglutarate follows the lysine metabolic pathway so may be of less benefit with lysine. So, arginine pyroglutamate and l-lysine 1:1 at 1200 mg each (or higher is the substantiated formula. If you are considering a bulk buy to reduce cost, here's one that's within dollars of the next product and the 1:1 formula to match the Isidori study. http://www.ebay.com/itm/L-Arginine-Pyroglutamate-Lysine-Powder-1000-Grams-/33052\ 2759261 I'll probably buy mine from a different dealer but it will be the same formula, instead of Life Extension's arginine ketoglutarate/ornithine ketoglutarate I bought last time. LEFs seems to be " working " on Jo's hot flashes, which have reduced in frequency in three months from four during the night and three daily to none at all most days, even with a potentially flooded lysine metabolism pathway due to adding LEF l-lysine to the LEF formula. Other than anti-aging she's not treating perimenopausal symptoms. I think we've anti-aged her again in this round So don't rule out the LEF formula but the bulk Arginine-Pyroglutamate-Lysine buy is pretty inexpensive. You'd mix a tsp in a glass of 5-alive, lemon or orange juice, and I've learned you can benefit by doing it up to 4 times daily. I'd been suggesting it would work in theory but it appears to be substantiated. http://www.ebay.com/itm/L-Arginine-Pyroglutamate-Lysine-Powder-1000-Grams-/33052\ 2759261 All good, Duncan Crow One of Curezone.com's Best Health Sites http://members.shaw.ca/duncancrow Quote Link to comment Share on other sites More sharing options...
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