Proton magnetic resonance spectroscopy and magnetic resonance imaging findings

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1: J Neuroimaging. 2004 Oct;14(4):377-9.

Proton magnetic resonance spectroscopy and magnetic resonance

imaging findings in a patient with central nervous system

paracoccidioidomycosis.

Faria AV, Dabus GC, Zanardi VA, Cendes F.

Department of Radiology, University of Campinas-UNICAMP, Campinas,

SP, Brazil.

The authors describe a patient with brain paracoccidioidomycosis

whose magnetic resonance image (MRI) showed multiple hypointense

lesions on T2-weighted images with peripheral enhancement after

gadolinium injection. Single-voxel proton magnetic resonance

spectroscopy (H-MRS) of one of the lesions showed 2 peaks at 0.9 and

1.32 ppm, corresponding to lipid signals, indicating intense

necrosis. The other characteristic peaks of H-MRS were

undifferentiated from baseline. These findings, although not

specific, may help to differentiate fungal abscess from tumoral

lesions and other types of abscess.

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