Biochemical changes in the serum of patients with chronic toxigenic

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1: ScientificWorldJournal. 2003 Nov 3;3:1058-64.

Biochemical changes in the serum of patients with chronic toxigenic

mold exposures: a risk factor for multiple renal dysfunctions.

Anyanwu E, AW, Vojdani A, Ehiri JE, Akpan AI.

Neurosciences Research, Cahers Inc., Conroe, TX, USA.

ebereanyanwu@...

This paper analyzes and presents the biochemical abnormalities in

the sera of patients presenting with chronic mycosis in order to

investigate the relationship with the risks of multiple renal

disorders. The study population (n = 10) consisted of six females

and four males (mean age 36.3 years) exposed by toxic molds in their

homes and offices for an average of 2.8 years. The control group

comprised ten people, five males and five females (mean age 35.9

years) without any known exposures to toxic molds. Blood samples

were obtained from both the patients and the controls and were

processed using specific biochemical methods that included enzyme-

linked immunoabsorbent assay (ELISA). There were biochemical

abnormal concentrations in creatinine, uric acid, phosphorus,

alkaline phosphotase, cholesterol, HDH, SGOT/AST, segmented

neutrophils, lymphocytes, total T3, IgG and IgA immunoglobulins with

significant differences between patients and controls. These

abnormalities were consistent with multiple renal disorders. The

major complaints of the mycosis patients were headaches, pulmonary

symptoms, allergic reactions, memory loss, skin rashes, blurred

vision symptoms, fatigue, and runny nose. These findings were

depictive of a strong association of chronic mycosis with abnormal

renal indicators. It was concluded that, although this research was

a pilot investigation, based on the overall results, people exposed

to chronic indoor environmental toxic molds were at risk of multiple

renal complications.