The diagnosis and surgical treatment for 56 cases

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1: Zhonghua Wai Ke Za Zhi. 2004 Oct;42(10):614-6. Related Articles,

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[The diagnosis and surgical treatment for 56 cases with pulmonary

and pleural aspergillosis]

[Article in Chinese]

Wu ZY, Su Q, Zhou YL, Ni YM, Ye DS.

Department of Cardiothoracic Surgery, The First Affiliated Hospital,

Medical College of Zhejiang University, Hangzhou 310003, China.

OBJECTIVE: To summarize the experience of diagnosis and surgical

treatment for pulmonary and pleural aspergillosis. METHODS: The

clinical data of cases with pulmonary and pleural aspergillosis were

analyzed retrospectively between September 1972 and June 2003. There

were 53 cases with pulmonary aspergillosis and 3 cases with pleural

aspergillosis. Aspergillus was found preoperatively in 8 patients by

sputum culture (5 cases) or needle biopsy of the lung (2 cases) or

fibrobronchoscopic biopsy (1 case). All patients were treated with

surgical procedures following X-ray film or CT scan. RESULTS: Of 53

cases with pulmonary aspergillosis, 42 lobectomies, 3

segmentectomies, and 8 wedge resections were performed. Of three

cases with pleuralaspergillosis following eliminating their diseased

foci in residual pleural space, two underwent thoracoplasty, one

underwent postoperative closed chest drainage for one and an half

month with fluconazole injected into residual pleural space

repeatedly for 1 month (200 mg/100 ml, 1 time per 2 or 3 days). No

operative death and major postoperative complications occurred. None

of the patients had recurrent symptoms at follow-up. CONCLUSION: We

recommend aggressive surgical resection for pulmonary and pleural

aspergillosis, and the surgical result is excellent.

PMID: 15265407 [PubMed - in process]