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Fatal encephalitis caused by Ochroconis gallopavum in a domestic cat

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=pubmed & dopt=Abstract & list_uids=8064545

1: J Med Vet Mycol. 1994;32(2):141-5.

Fatal encephalitis caused by Ochroconis gallopavum in a domestic cat

(Felis domesticus)

Padhye AA, Amster RL, Browning M, Ewing EP.

Emerging Bacterial and Mycotic Diseases Branch, Centers for Disease

Control and Prevention, Atlanta, Georgia 30333.

Ochroconis gallopavum was identified as the causal agent of fatal

encephalitis in a young, short-hair, domestic cat. The cat initially

developed an ulcerated mass on the left side of the tongue and signs

of pain in the abdomen. The tongue lesion was surgically removed and

exploratory abdominal surgery revealed abnormalities suggestive of

pancreatitis and peritonitis. During the month after surgery, the

cat's health declined, manifested by sluggishness, loss of appetite

and abnormal behaviour. Following a final rapid deterioration, the

cat became non-responsive and was euthanized. Histologic examination

of the brain, lung and mediastinal lymph node lesions revealed large

numbers of pigmented, septate, branched, hyphal elements with

swollen intercalary and terminal vesicles, and short chains of

moniliform hyphal cells. Cultures of the mediastinal lymph nodes

yielded a dematiaceous, thermotolerant fungus that was identified as

O. gallopavum. This report describes the first well-documented

infection in a cat caused by O. gallopavum.

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