Intracranial aspergillosis in a non-immunocompromised patient treated for muscle

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8172 & date=2004 & volume=11 & issue=8 & spage=666

International Journal of Urology

Volume 11 Issue 8 Page 666 - August 2004

doi:10.1111/j.1442-2042.2004.00850.x

Case Report

Intracranial aspergillosis in a non-immunocompromised patient

treated for muscle-invasive bladder cancer

AXEL STUART MERSEBURGER1, MATHIAS OELKE2, JOERG HARTMANN3, ARNULF

STENZL1 AND MARKUS ANTONIUS KUCZYK1,2

Abstract We report a case of intracerebral Aspergillosis in a

patient undergoing radical cystectomy for the treatment of muscle-

invasive bladder cancer who did not reveal any deterioration of the

immune system. Aspergillus fumigatus is an ubiquitously present,

airborne fungus that tends to infect the upper respiratory tract.

However, the latter was not observed in the patient presented.

Complications in the form of an involvement of the central nervous

system are very rarely recognized as a result of an Aspergillus

infection and primarily occur in patients who are not

immunologically competent. To our knowledge, we present the first

case of intracerebral invasive Aspergillosis in an otherwise healthy

patient diagnosed with an urological malignancy.