Aspergillus mycotic aneurysm--case report.

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: Neurol Med Chir (Tokyo). 1991 Jun;31(6):346-50. Related Articles,

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Aspergillus mycotic aneurysm--case report.

Komatsu Y, Narushima K, Kobayashi E, Tomono Y, Nose T.

Department of Neurosurgery, Tsukuba Memorial Hospital, Ibaraki,

Japan.

A 61-year-old female developed subarachnoid hemorrhage after trans-

sphenoidal surgery for Rathke\'s cleft cyst. Neuroradiological

examination revealed a large aneurysm at the C1 portion of the right

internal carotid artery. Autopsy revealed marked proliferation of

aspergillus hyphae in the wall of the aneurysm. A review of

previously reported cases of fungal aneurysm proposes two

developmental processes. Aneurysms secondary to fungal meningitis

tend to be large in size and located in the major cerebral artery

trunk, but aneurysms following fungal sepsis tend to be small and in

peripheral branches. The former aneurysms are probably caused by

fungus invasion into the intracranium, usually from the paranasal

sinus, and the latter may be due to fungal emboli like bacterial

emboli in bacterial endocarditis. Ruptured fungal aneurysms are

difficult to treat, so fungal meningitis or sepsis must be

eradicated before an aneurysm develops.

Publication Types:

Case Reports

Review

Review of Reported Cases

PMID: 1724300 [PubMed - indexed for MEDLINE]