Re: Anti-Fungus Drug Useful for Sinus Problem

[Guest guest]

Thank you, tigerpaw. Dr Dennis (ENT) in Atlanta uses this in

the treatment of nasal and sinus fungus - often candida (yeast).

It was successful in my case - no problems at all. Also uses

Agricept, which is a grapefruit seed extract based nasal spray that

kills inhaled molds in sinus cavities (compounding pharmacy makes it

up) among some other products.

Dr Dennis strongly believes that many of our problems start with what

we are inhaling in our environments. The sinus cavities are not just

a lining. They are cells that can absorb and deseminate toxins into

our bodies through our sinuses. He is a proponent of FIXING your

living environment - doing whatever you have to do to break the chain.

Thansk for the info.

winslake

--- In , " tigerpaw2c " <tigerpaw2C@n...>

wrote:

>

> http://www.reuters.com/newsArticle.jhtml?

> type=healthNews & storyID=7374133

>

> By J. Brown, MD

> NEW YORK (Reuters Health) - Treatment with a nasal spray containing

> the anti-fungal drug amphotericin B reduces the swelling and

> inflammation that occurs with chronic rhinosinusitis, a common

cause

> of stuffy nose and facial pain, new research shows.

>

> Amphotericin B is an old drug that can cause serious side effects,

> particularly to the kidneys. However, when given as a nasal spray,

> the drug does not get absorbed, effectively avoiding these effects,

> researchers report in the Journal of Allergy and Clinical

> Immunology.

>

> The findings, which stem from a study of 30 patients, lend weight

to

> the notion that fungi are involved in the development of chronic

> rhinosinusitis.

>

> In an interview with Reuters Health, lead author Dr. Jens U.

> Ponikau, from the Mayo Clinic in Rochester, Minnesota, said that

> fungi appear to play a key role in chronic rhinosinusitis by

causing

> certain immune cells to show up in the mucous layer of the nose.

> Once there, the cells release toxic compounds that damage the

fungi,

> but also the surrounding nasal tissue.

>

> Still, the hypothesis that fungi are involved in chronic

> rhinosinusitis is controversial and it remains to be determined why

> only certain people develop the condition when nasal fungi are so

> common, Ponikau noted.

>

> He and his colleagues reasoned that if the immune cells are in the

> mucous membranes because of the fungi, then maybe reducing the

fungi

> would reduce the inflammation caused by the immune cells

> and " ultimately improve the patient's symptoms. "

>

> Compared with inactive " placebo, " 6 months of treatment with

> amphotericin B nasal spray led to a significant reduction in mucous

> swelling, as determined by CT scans and other tests. Moreover, such

> therapy seemed to reduce the number of immune cells present.

>

> " These findings have completely changed the way we approach

> sinusitis patients at Mayo, " Ponikau noted, adding that " thousands

> of chronic rhinosinusitis patients are now being treated with

> antifungals. "

>

> Larger studies will begin later this year, he said.

>

> SOURCE: Journal of Allergy and Clinical Immunology, January 2005.