Down's Syndrome and Iodine

[Guest guest]

Does anyone have some good research links on Down's Syndrome and Iodine???? Zoe

[Guest guest]

Unfortunately, I don't. I wish I did. I tried looking and all I

really saw was articles talking about destroying the thyroid when

having problems.

>

> Does anyone have some good research links on Down's Syndrome and

Iodine???? Zoe

>

[Guest guest]

> From: " " sandrapd2002@...

> Date: Sun May 21, 2006 3:52pm(PDT)

>Subject: Re:

>

>Unfortunately, I don't. I wish I did. I tried looking and all I

>really saw was articles talking about destroying the thyroid when

>having problems.

One must always be cautious with the Internet. Not everything on it is

true. But, then not everything the medical profession tells you is true

either, so one must apply their own logic to it.

Doing a simple Internet search, here's a few things of interest regarding

Down's Syndrome and iodine/hypothyroidism (note, fluoride displaces iodine

so what is reported below likely could have been corrected with adequate

iodind intake, but I believe these areas referred to are in the goiter belt,

a part of North America that has very little iodine) -

http://www.fluoridealert.org/downs-syndrome.htm

Seeking an explanation for these remarkable coincidences, he considered the

possibility that an environmental agent might b involved. He recalled that

in 1853 Chatin had linked goiter and cretinism, another birth defect, with

drinking water and had established a lack of iodine as the culprit. Rapaport

also observed that many of the mongoloid children had mottled teeth and,

apparently, an unusually low incidence of dental caries (23). All these

circumstances directed his attention to the fluoride content of the Green

Bay water supply, which indeed turned out to have a comparatively high

natural fluoride content: 1.2-2.8 ppm -- much higher than in most other

Wisconsin communities.

He then pursued this lead and ascertained the place of birth of all

mongoloid children living in institutions as of July 1, 1956, in the four

states of Wisconsin, North and South Dakota, and Illinois, and grouped them

according to the published fluoride content of the municipal drinking water.

In a tabulation of the 687 urban cases he found a statistically significant,

two-fold greater prevalence or risk of mongoloid births in communities with

1 ppm or more fluoride than in those with little or none in the water. He

presented these findings to the French National Academy of Medicine in Paris

in November 1956 (25).

How reliable are these discoveries? An application of Van Valen's formula

(26) reveals a combined statistical probability of less than 1 in 125,000

that the entire set of correlations from all four states was due to chance

(27). The same parallelism between the prevalence of mongolism and the

fluoride content of drinking water at the place of birth subsequently

corroborated by data supplied by 46 superintendents of institutions in other

areas of the United States (28).

***************************

http://www.einstein-syndrome.com/health_medical/thyroid_doc_don.htm

I work with a lot of Down's Syndrome kids and I am beginning to feel that

much of what people call Down Syndrome is just Cretinism (mental retardation

due to untreated or undertreated hypothyroidism in children). The short

stature, puffy and dry skin, slowed metabolism, constipation, vulnerability

to cardiovascular disease and serious infections, a tendency toward weight

gain, and even the intellectual handicap are as much a part of Cretinism as

Down Syndrome.

**************************

http://www.pathguy.com/lectures/thyroid.htm

NOTE: Down's syndrome folks often (at least 50% of the time) get at least a

lymphocytic thyroiditis, and they may end up hypothyroid. Don't overlook

this, or assume the mental slowness is just part of Down's.

*****************************

http://thyroid.about.com/cs/toxicchemicalsan/a/flouride_2.htm

Studies dating back to the 1950s have shown links between Down's Syndrome

and natural fluoridation. Ionel Rapaport also showed how the age of women

bearing Down's Syndrome children decreased in direct relation to the

increase of fluoride in the water supply. The more fluoride that was in the

water, the younger the age of the women bearing Down's Syndrome children.

****************************

The effects of thyroid deficiency and fluoride poisoning are approximately

the same. Maybe because fluoride displaces iodone. These are symptoms for

both, and notice the long list of symptoms either can cause. This could get

you to thinking about all the problems that can be cause by low thyroid, not

just the weight gain among middle age women that most doctors think about -

http://www.bruha.com/pfpc/html/symptoms.html

****************************************

I've corresponded with a woman who's child had terrible problems. She was

diagnosed as autistic, when she pursued it and her child was diagnosed as

hypothyroid via a TRH test, the child got much better. TRH is produced by

the hypothalamus, which goes to the pituitary to tell it to produce TSH,

which goes to the thyroid and tells it to produce T4 and T3. Here's

something on that -

http://www.down-syndrome.net/library/periodicals/dsrp/06/1/025/dsrp-06-1-025-EN-\

GB.htm

Several aspects of thyroid disorders in the Down syndrome population have

been further investigated. Criscuolo et al (1986) and Sharav et al, (1991)

have suggested that in persons with Down syndrome subclinical primary

hypothyroidism could be diagnosed by testing the

hypothalamic-pituitary-thyroid pathway by detection of an exaggerated and

prolonged TSH response to TRH (thyrotrophin releasing hormone).

**********************************

What they miss below is that some who appear clinically (by observation and

history) hypothyroid, but not " biochemically " get better on thyroid hormone.

The labs are not perfect science or even close. Thus, in many cases, the

proof of hypothyroidism is with symptoms improving with treatment -

http://www.down-syndrome.net/library/periodicals/dsrp/06/1/025/dsrp-06-1-025-EN-\

GB.htm

As thyroid disorders are difficult to diagnose in people with Down syndrome

there should be a " high index of clinical suspicion " . In view of the low

cost of screening for thyroid disorders, the potential benefits of

treatment, and the lack of a clear correlation between clinical and

biochemical indications of thyroid disorders, thyroid function tests should

be regularly performed (see management).

****************************

Both the cost and risk of thyroid treatment are low in comparison to the

continued intellectual impairment of a child. Armour Thyroid is the most

fool proof, as Synthroid does not work for everyone, and not everyone

converts T4 to the active T3 very well. For example if someone has impaired

liver function, it inhibits their inability to convert T4 to T3. Do Down's

patients have efficiently functioning livers?

Of course, all this could be caused by low iodine / selenium intake as both

are necessary for proper thyroid function.

Skipper

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[Guest guest]

> From: " " sandrapd2002@...

>Unfortunately, I don't. I wish I did. I tried looking and all I

>really saw was articles talking about destroying the thyroid when

>having problems.

First, hypothyroidism / iodine deficiency are so linked, it's probably hard

to tell if any case of hypothyroidism is caused by iodine deficiency. Even

if iodine deficiency isn't the current solution, it may be the reason for

the progression to hypothyroidism. It's likely a cause of both hypo and

hyper thyroidism. (Did you know Vitamin C deficiency can also cause

hyperthyroidism, and some people have had their thyroids removed simply

because they were Vitamin C deficient per Langer, MD in one of his

books probably " Solved the Riddle of Illness. " )

Anyways, I quoted this excerpt to you about testing for hypothyroidism via

the TRH test -

http://www.down-syndrome.net/library/periodicals/dsrp/06/1/025/dsrp-06-1-025-EN-\

GB.htm

Several aspects of thyroid disorders in the Down syndrome population have

been further investigated. Criscuolo et al (1986) and Sharav et al, (1991)

have suggested that in persons with Down syndrome subclinical primary

hypothyroidism could be diagnosed by testing the

hypothalamic-pituitary-thyroid pathway by detection of an exaggerated and

prolonged TSH response to TRH (thyrotrophin releasing hormone).

**********************************

I brought this to your attention, because this mentions the TRH test, one

test that can catch hypothyroidism when some of the other tests miss. I

assume this means there's a problem with the hypothalamus as what they

really do is give the pituitary an injection to stimulate TSH. Having an

abnormal response to the TRH implies it wasn't receiving enough from the

hypothalamus, thus the " exaggerated and prolonged TSH response " mentioned

above.

A woman whose child had autism was greatly relieved when her child was

finally diagnosed this way. The child was in bad shape. Here's the content

of a letter she wrote to her doctor.

I know Down's Syndrome and autism are different. Yet that doesn't mean they

can't have similar causes as hypothyroidism from iodine deficiency or other

causes can cause almost anything to go wrong.

This just goes to show you that the diagnostic tests are not perfect, as

this is one very seldomly used by doctors, yet it worked in her case, and

it's not a controversial test, just one typically considered unnecessary. I

exchanged emails with her a few times in 2001, and at that time which was 3

years after writing the letter, she believed at least in this case, and

maybe all of autism, it was really undiagnosed hypothyroidism.

Skipper

" Please bear with me but maybe I’ve stumbled on to one of the “keys” to

autism that has been greatly over-looked.

Actually credit should really go to Dr. Raphael Kellman, M.D., at The

Center for Progressive Medicine in New York and to Dr. , M.D.

(a DAN doctor) in Richland, WA - although neither of them know it yet.

A must to read is the article in the Alternative Medicine Magazine - Issue

22 that targets the “thyroid”. On the side bar there are three more

articles...one should read all three of them too. Please be aware none of

these articles mention “autism”....but concentrate on only the symptoms as

you are reading. Vicki Westlund recently made me aware of these articles via

the autism listserv.

According to Dr. Kellman the thyroid is one of the most over-looked organs

in the body. The old means of testing were too cumbersome and time consuming

so was abandoned by most physicians - they opt to do the T4 or TSH.

According to Kellman 90% of the medical problems today result from lack of

proper attention and testing of the thyroid and it’s functioning.

We are mainly talking about “hypothyroidism” - an underfunctioning of the

thyroid. There are a variety of causes: hereditary, environmental,

chemo/radiation, excess hormones in processed meats, mercury (fillings in

teeth - immunizations), excess iodine (table salt), etc.

Once damage to the thyroid takes place it affects all the other

organs....starting with digestion and absorption. Now toxin’s start building

in the system. You can have an array of symptoms: weight gain/weight loss

depending on the type of metabolism you had to begin with. Creating no

appetite or binge eating. Bloating, fluid retention, skin problems (itching,

eczema, psoriasis, acne, hives & other skin eruptions, skin pallor or

yellowing).

The immune system also starts to deteriorate since the necessary vitamins,

minerals, are not being absorbed, also creating problem’s with amino acids.

Two more problems are created: (1) repeated infections and (2)cold’s and

upper respiratory infections.

Now let’s add a bunch of antibiotics...to treat these two problems...there

goes the good bacteria..allowing candida yeast to take over which results

IgG (delayed food allergies) and also opening the doors to introduction of

viruses and parasites.

Other symptoms of an underfunction thyroid are: depression, low body

temperature, infertility, menstrual disorders, memory disturbances,

concentration difficulties, paranoia, migraines, over-sleeping and/or the

inability to sleep due to gastrointestinal discomforts or anemia, “laziness”

(no motivation), muscle aches and or weaknesses (low muscle tone), hearing

disturbances (burning, prickly sensations or noises in the head), slow

reaction time and mental sluggishness, labored breathing, hoarseness, speech

problems, brittle nails and poor vision and/or light sensitivity.

All of Dr. Kellman’s patient’s have a wide variety of symptoms but all have

malabsorption, defficiencies in vitamins and minerals, this creates chemical

imbalances resulting in neurotransmitting problems.

If the above should take place in a non-verbal child, let’s say before they

acquire speech - you would get the diagnosis of a “mute” autistic child.

Let’s say the child had begun to talk...but due to the thyroid

problem...lost speech - they would get the diagnosis or label of PDD/Autism.

A child affected later might be considered high functioning.

Children with candida, food allergies, immune system dysfunctions, viruses

that go undetected might show degrees of improvement with the various

treatments whether it be IV therapy, anti-viral, nutritional intervention,

or maybe a change in environment...but all continue to deteriorate if these

treatment’s are stopped. WHY????? Because one thing is being over-looked...a

“thyroid dysfunction”...and the standard test are so inaccurate.

Dr. Kellman says that the normal means of testing that most physician’s use

T3, T4, and TSH all may result in a normal reading....but it does not

reflect the actual functioning level of the thyroid.

Dr. Kellman says the only reliable test is the TRH, but due to the fast

paced assembly line of modern medicine...it was a cumbersome and time

consuming test so Dr.’s abandoned it opting to use the TSH in it’s place.

The TRH test has since been greatly improved over the old technique.

First a pre-TSH is taken.

An injection of Tyrel(Protirelin)TRH is given directly into the vein via a

butterfly.

A post-TSH is taken in exactly 25 minutes.

There are no adverse or dangerous side effects. Everyone experiences a “30

second” wave of nausea and/or the feeling they have to urinate...they do

neither..it is just a feeling. They may also experience a slight drop or

rise in their blood pressure...but that is very temporary.

If the second (or post-TSH) reading is 10...that indicates a low

functioning thyroid, if it’s 15 a moderate low functioning of the thyroid,

and if 20 a severe low functioning thyroid.

Dr. Kellman primarily deals with teenager’s or adults.

Dr. test the thyroid by NAET (muscle testing) but is finding

hypothyroidism in 100% of the autistic children he deal’s with.

None of the research I’ve seen so far mentions...or target’s the

“thyroid”...not one word in the DAN or Goldberg’s reports...or any of the

autism research I’ve seen.

In our case for example...my husband had a benign nodule (½ his thyroid)

removed in 1992...which was only detected when the nodule got so enlarged he

could actual see and feel it and had discomfort when swallowing...it was not

detected by his normal thyroid testing which did not include the TRH...they

always came back normal...these test were done yearly due to his work

physical requirements. We have no ideal how long the condition existed prior

to it’s detection.

My daughter, Angie, was born December 13, 1988, she had 4 out of 5

reactions to DPT..the lot being pulled 4 times, but nothing ever recorded by

Dr. or reported by him. She was a very normal baby until 18 months of

age...then almost changed over night. By this time she had had 15 doses of

“mercury” in immunizations and multiple upper respiratory infections, ear

infections, etc. These were treated with truck loads of

antibiotics...constantly for about 6 years.

She went through as I remember various problems with the intestinal track -

spastic colon (little balls), clay colored mushy stuff, then severe

constipation. Stool softeners didn’t work, mineral oils made her vomit and

for the next 3 years she had to have enemas on a daily basis..and then the

bowels barely moved. The pediatrician called it “psychological

constipation”....normal for “kid’s like this”...we would just have to live

with it. She also lost all speech.

She totally refused food, lived solely on ProSobee Baby formula for 3 ½

years...would projectile if food came within three feet of her.

Also, during this period was constantly sick...ear infections, sore

throats, viruses, bronchitis, chicken pox twice..the second time so severe

she had to have IV’s for 27 hours, she had hives, itched all the time (still

does), had eczema on scalp, yeast rash on bottom several times, seasonal

allergy symptoms 95% of the time, thin hair, white skin (which is now very

yellow), thin hair, thin peeling finger nails. She plugged her ears until

they bled, gagged and projectile vomited a lot, and her eyes were very

sensitive to light and she rubbed them constantly.

She lived on antibiotics from 18 months until October of 1996.

In 1995 she was diagnosed by Carl Pfeiffer as severe zinc deficient with a

very high zinc/copper ratio, and had many vitamin/mineral imbalances and

chemical imbalances.

She was on their program 1 year...gained 5 lbs..but not a lot of

improvement. She still had lot’s of upper respiratory and ear infections,

did start saying a word or two, and did starting a little food. I informed

Dr. Glabb about the DAN protocol...she was not a DAN doctor at that time.

In October of 1996, we had her allergy tested at Immuno Labs...the results

were: no immediate allergies, 29 out of 209 IgG delayed food allergies which

included casein and gluten..no Candida at that time but has since acquired

it. I put her on a rotation diet...she acquired an appetite for the first

time in her life. I also at the same time put her on an array of

supplements..vitamins/minerals, extra zinc, herb’s....everything I could

possibly find to boost the immune system. She gained 10 lbs...but still had

burping, belching, gas and sluggish bowels.

About the same time we got a computer and internet access and I jointed the

autism listserve where I encountered Vicki Westlund. She talked me into

another hair analysis in August of 1997. Angie was low in Calcium, Sodium,

Potassium, Copper, Zinc and Germanium and showed absolutely NO iron,

manganese, Chromium, Cobalt or Silica...she also showed traces of “mercury”

and “aluminum”...but within the normal range. Also she was low in most

additional minerals.

After Vicki’s analysis’s and with the help of Dr. Moreno...we switched her

supplemental program, also added Olivir, Piracetam and Soil Based Organisms.

Her appetite increased and her immune system improved and her bowel’s

started functioning without enemas, although still sluggish. She also has

gone from saying just a couple of words to eight word sentences.

All the supplement’s in the world won’t help though if she is suffering

from an underactive thyroid.

We are now on our 4th doctor and after a two week battle and numerous phone

calls to New York and Dr. Kellman’s office he (Dr. Kiel) reluctantly agreed

to run a TRH on Angie. (Most doctor’s initial request to a TRH is comparable

to asking them to do their first amputation in the office blindfolded.) They

are convinced the T3, T4 and TSH means of testing are accurate. Dr. Kellman

however, deems them totally inaccurate!

Friday...I just got Angie’s result’s on the TRH...her pre-TSH was

2.906ulU/ml the normal range (0.35 - 5.50).....her post-TSH reading was

44.035ulU/ml the normal range (0.35 - 5.50). The excess secretion of thyroid

hormone indicate that Angie’s thyroid is barely functioning...if it were

functioning she would be converting the thyroid hormone into T3 & T4's.

I called Dr. Kellman and he confirmed that this definitely indicates she

has severe hypothyroidism......!

If we can catch and detect their low functioning thyroid problems

early...we could possible reverse or prevent a lot of the other problems

from even occurring. I believe there is a good chance that AUTISM is just a

hypothyroidism problem that is undiagnosed and untreated in most

children....thereby creating a multitude of chains of events to occur.

I believe it would be well worth the DAN doctor’s time and effort’s to

start doing the TRH test on their patients.

Please let me know what you think?????

Very truly yours,

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[Guest guest]

Thanks Skipper! You always have so much information!

What I was saying what I found on the internet was pretty much the

treatment of hyperthyroid patients with iodine or something. Not

much else.

I have never heard in any of my reading that people with DS have

increased liver problems. The main problems are: increased risk of

thyroid problems, heart defects at birth, leukemia, hypotonia (low

muscle tone - which is why there is an increased risk of

constipation - the muscles down there aren't as strong) and

alzheimers (or something similar to it as they age). I'm sure there

are a few more that I am forgetting but I have never read anything

about the liver (that I remember anyway). Also, I was told by my

son's dentist that people with DS have fewer cavities (I saw

something about that in your findings). The only weird thing about

my sweety's teeth so far is that they are overcrowded and sharp!

My son's thyroid tests showed normal last week (whatever that

means), but they only did two tests (T4 is at 0.94 (range 0.6-1.64)

and TSH is 1.815 (range 0.34-5.6). I am still working on getting

his temps, but since he really doesn't have hypo symptoms (thank

God), then I think for now he is ok. I e-mailed the genetic

specialist about his results and told her I am concerned especially

since I have thyroid problems and she definitely said we need to

watch him closely for any signs that he is starting to have

problems. I asked her about doing the other tests, and of course I

was told it wasn't necessary right now. If his temperature readings

show weird (I am now waiting until he is over his cold because I

kept getting 99.0 readings - I want his regular temperature readings

now) then I will take him to his pediatrician for a visit and ask

them to please do the other tests.

I am still trying to figure out what is meant by " puffy face " . I

keep looking at his face trying to decide if it is puffy. It is

definitely cute, but I'm not sure about puffy. :-)

Do Down's

> patients have efficiently functioning livers?

>

> Of course, all this could be caused by low iodine / selenium

intake as both

> are necessary for proper thyroid function.

>

> Skipper

>

> _________________________________________________________________

> Express yourself instantly with MSN Messenger! Download today -

it's FREE!

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[Guest guest]

Constipation in down syndrome; this study shows significant lower magnesium

levels in down syndrome. This is the most likely cause of the constipation.

Trace element profiles in individual blood cells from patients with Down's

syndrome.

The concentrations of trace elements in three different types of blood

cells--erythrocytes, thrombocytes and neutrophils--were determined by nuclear

microprobe analysis in 11 children with Down's syndrome (DS) and compared with

those in 13 controls. The median concentration of copper in all three types of

blood cells and that of calcium in erythrocytes were significantly higher in DS

children than in controls. In contrast, the median levels of zinc in

erythrocytes, of manganese and iron in erythrocytes and neutrophils, and of

magnesium in erythrocytes and thrombocytes were significantly lower in DS than

in control children. In 10 of the 11 DS children, detectable erythrocyte levels

of titanium were found, which is remarkable, since this was not observed in any

of the cells from the control children.

PMID: 3158149 [PubMed - indexed for MEDLINE]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=3\

158149 & dopt=Abstract

--- <sandrapd2002@...> wrote:

> Thanks Skipper! You always have so much information!

>

> What I was saying what I found on the internet was pretty much the

> treatment of hyperthyroid patients with iodine or something. Not

> much else.

>

> I have never heard in any of my reading that people with DS have

> increased liver problems. The main problems are: increased risk of

> thyroid problems, heart defects at birth, leukemia, hypotonia (low

> muscle tone - which is why there is an increased risk of

> constipation - the muscles down there aren't as strong) and

> alzheimers (or something similar to it as they age). I'm sure there

> are a few more that I am forgetting but I have never read anything

> about the liver (that I remember anyway). Also, I was told by my

> son's dentist that people with DS have fewer cavities (I saw

> something about that in your findings). The only weird thing about

> my sweety's teeth so far is that they are overcrowded and sharp!

>

> My son's thyroid tests showed normal last week (whatever that

> means), but they only did two tests (T4 is at 0.94 (range 0.6-1.64)

> and TSH is 1.815 (range 0.34-5.6). I am still working on getting

> his temps, but since he really doesn't have hypo symptoms (thank

> God), then I think for now he is ok. I e-mailed the genetic

> specialist about his results and told her I am concerned especially

> since I have thyroid problems and she definitely said we need to

> watch him closely for any signs that he is starting to have

> problems. I asked her about doing the other tests, and of course I

> was told it wasn't necessary right now. If his temperature readings

> show weird (I am now waiting until he is over his cold because I

> kept getting 99.0 readings - I want his regular temperature readings

> now) then I will take him to his pediatrician for a visit and ask

> them to please do the other tests.

>

> I am still trying to figure out what is meant by " puffy face " . I

> keep looking at his face trying to decide if it is puffy. It is

> definitely cute, but I'm not sure about puffy. :-)

>

>

>

>

> Do Down's

> > patients have efficiently functioning livers?

> >

> > Of course, all this could be caused by low iodine / selenium

> intake as both

> > are necessary for proper thyroid function.

> >

> > Skipper

> >

> > _________________________________________________________________

> > Express yourself instantly with MSN Messenger! Download today -

> it's FREE!

> > http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/

> >

>

>

>

>

>

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