Guest guest Posted April 28, 2008 Report Share Posted April 28, 2008 I just ordered ATP cofactors, but I realize that I'm already taking 65 mg B2 and 100 mg B3 within my other supplements. Is it ok to still take 2 ATP cofactors pills a day? Thanks, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2008 Report Share Posted April 29, 2008 What happened to me was I was taking my Iodine with the ATP cofactors and after about 3 and a half weeks I became very depressed and hardly functioning, thinking maybe I was detoxing or something. Was ready to give up on the iodine when I decided, after trying several things, to take a 100B-complex tablet. I remember reading that you shouldn't take any b vitamins in isolation without adding all the B's or else you can acquire a deficiency one of them if they are not in balance. So almost immediately after taking the 100 B-complex tablet I could feel the depression,etc. easing up and feeling much better after adding B-complex. Just thought I would mention this in case anyone has noticed the same effect and wondering what is wrong. Need a new ride? Check out the largest site for U.S. used car listings at AOL Autos. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2009 Report Share Posted October 2, 2009 They are talking about 2,500 mgs of Niacin. That's a HUGE amount compared to ATP Co-factors. The vitamins B2 and B3, as precursors of the cofactors FADH2 and NADH, play a key role in ATP synthesis4 and in the generation of intracellular hydrogen peroxide.5 Hydrogen peroxide formation is the ratelimiting step in the oxydation of iodide to iodine by iodoperox-idases, including thyroid peroxydase (TPO). The oxydation of intrathyroidal iodide to iodine by TPO is the first and key step in the synthesis of thyroid hormones. Notice they state there is no significant change in TSH and FT4 levels. FT4 is an active hormone. They didn't mention FT3 which is the metabolic hormone. It doesn't look like the individuals were hypothyroid. Steph atp cofactors i ran across this statement.... Evidence suggests niacin supplementation can influence thyroid hormone levels in at least some individuals. One author reported cytopenia and hypothyroxinemia with a concomitant decrease in thyroxine-binding globulin in two patients receiving niacin. All thyroid function tests returned to normal after niacin supplementation was discontinued.[118] The impact of sustained supplementation with niacin (mean daily dose of 2.6 grams for an average duration of 1.3 years) was observed in one female and four male subjects with hyperlipidemia. Before and after thyroid function studies revealed significant decreases in serum levels of T4, T3, and TBG, with no significant alterations in fT4 and TSH levels. Discontinuation of niacin resulted in a return to pretreatment levels of these parameters of thyroid function.[119] While results suggest niacin can influence serum thyroid hormone concentrations, it is currently not known whether this is a centrally-mediated result, a direct result of a decrease in TBG, or a niacin-induced alteration in some aspect of peripheral conversion. However, since TSH was unaltered, evidence suggests an influence outside the hypothalamic-pituitary-thyroid axis. if i am reading this right niacin could negatively affect thyroid hormone output....and some of us take the ATP cofactors which i believe have niacin .....can anyone help me figure out if i am reading this right?? we added the atp cofactors when we started iodine.... Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 2, 2009 Report Share Posted October 2, 2009 well, if this is an issue i will just not use it. i can't use statins, will not use statins, and this was to help with the heart disease. whatever. what will be will be i guess. diane, near philly, pa On Oct 2, 2009, at 5:21 PM, dawn volz wrote:i ran across this statement....Evidence suggests niacin supplementation can influence thyroid hormone levels in at least some individuals. One author reported cytopenia and hypothyroxinemia with a concomitant decrease in thyroxine-binding globulin in two patients receiving niacin. All thyroid function tests returned to normal after niacin supplementation was discontinued.[118]The impact of sustained supplementation with niacin (mean daily dose of 2.6 grams for an average duration of 1.3 years) was observed in one female and four male subjects with hyperlipidemia. Before and after thyroid function studies revealed significant decreases in serum levels of T4, T3, and TBG, with no significant alterations in fT4 and TSH levels. Discontinuation of niacin resulted in a return to pretreatment levels of these parameters of thyroid function.[119]While results suggest niacin can influence serum thyroid hormone concentrations, it is currently not known whether this is a centrally-mediated result, a direct result of a decrease in TBG, or a niacin-induced alteration in some aspect of peripheral conversion. However, since TSH was unaltered, evidence suggests an influence outside the hypothalamic-pituitary-thyroid axis.if i am reading this right niacin could negatively affect thyroid hormone output....and some of us take the ATP cofactors which i believe have niacin .....can anyone help me figure out if i am reading this right?? we added the atp cofactors when we started iodine.... Quote Link to comment Share on other sites More sharing options...
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