Adaptation to Iodine Deficiency in Rats: Thyroid Status Is Tissue Specific

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http://endo.endojournals.org/cgi/content/abstract/147/5/2098

The novel and important finding of our study is that thyroid status

cannot be defined for the animal as a whole: at all grades of ID, T3 is

simultaneously elevated, normal, and low in different tissues. Present

findings in mild-moderate ID draw attention to the importance, for man,

of the resulting hypothyroxinemia that may affect mental functions and

neurodevelopment of the inhabitants, even when they do not have the

increased TSH or clinical hypothyroidism, often wrongly attributed to

them.

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Ok, I think this is saying that with iodine deficiency...there can be

differing levels of T3 in various tissues....and therefore the low

thyroxine from ID....can affect mental functions/neurodevelopment...and

TSH may never reflect the hypothyroidism.

if this is not what it is saying....someone please correct. I think

this goes along with the previous abstract about brain hypothyroidism?

cindi