Guest guest Posted July 18, 2007 Report Share Posted July 18, 2007 ARE YOU LOOKING FOR HELP FROM MEDICAD ONLY OR ARE YOU ALSO TRYING TO GET SSI? LET ME KNOW AND I MAY E ABLE TO HELP. GEOFF GGATTON2@...carolyn wall <cwall29@...> wrote: I am looking for someone who knows a great deal about the Medicaid waiver's and what they cover? Does anyone know of someone that they can recommend? If so, please email their email address or make a post. I am trying to help a family and am having difficulty getting answers from the DFAC office. Thanks! Be a better Globetrotter. Get better travel answers from someone who knows. Answers - Check it out. Shape in your own image. Join our Network Research Panel today! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2008 Report Share Posted August 25, 2008 Hi Sheila The TSH test was invented by the makers of Synthroid in 1973. Chris > > As I have searched and searched and searched and cannot find an answer as to WHO invented the TSH test, I NEED to know if I am correct in thinking that I am having trouble finding articles because there probably are none of significance. Nor can I find if there was a leader of the concept of switching from clinical diagnosis completely to laboratory diagnosis. Am I correct in thinking this was done by CONSENSUS of endocrinologists in 1975 and that there have been NO STUDIES, either before or after. I cannot believe this, so if anybody can prove me wrong and cite medical research and studies I might have missed - I would be delighted....or would I? The implications of finding this was done by consensus ONLY would be appalling considering the thousands of sufferers who are not being given a diagnosis because their TSH is within a range that has been increased this past couple of years, for what reason, we do not know. > > Luv - Sheila > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2008 Report Share Posted August 25, 2008 Hi Sheila The makers of Synthroid being Abbott Laboratories. Chris > > As I have searched and searched and searched and cannot find an answer as to WHO invented the TSH test, I NEED to know if I am correct in thinking that I am having trouble finding articles because there probably are none of significance. Nor can I find if there was a leader of the concept of switching from clinical diagnosis completely to laboratory diagnosis. Am I correct in thinking this was done by CONSENSUS of endocrinologists in 1975 and that there have been NO STUDIES, either before or after. I cannot believe this, so if anybody can prove me wrong and cite medical research and studies I might have missed - I would be delighted....or would I? The implications of finding this was done by consensus ONLY would be appalling considering the thousands of sufferers who are not being given a diagnosis because their TSH is within a range that has been increased this past couple of years, for what reason, we do not know. > > Luv - Sheila > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2008 Report Share Posted August 25, 2008 How do you know - I need evidence and what studies did they base this invention on ? Can you poiont me in the right direction, I need to cite this. Luv - Sheila Hi SheilaThe TSH test was invented by the makers of Synthroid in 1973.Chris>> As I have searched and searched and searched and cannot find an answer as to WHO invented the TSH test, I NEED to know if I am correct in thinking that I am having trouble finding articles because there probably are none of significance. Nor can I find if there was a leader of the concept of switching from clinical diagnosis completely to laboratory diagnosis. Am I correct in thinking this was done by CONSENSUS of endocrinologists in 1975 and that there have been NO STUDIES, either before or after. I cannot believe this, so if anybody can prove me wrong and cite medical research and studies I might have missed - I would be delighted....or would I? The implications of finding this was done by consensus ONLY would be appalling considering the thousands of sufferers who are not being given a diagnosis because their TSH is within a range that has been increased this past couple of years, for what reason, we do not know.> > Luv - Sheila>No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.7/1632 - Release Date: 25/08/2008 07:05 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 25, 2008 Report Share Posted August 25, 2008 Hi Chris I have heard on other forums members saying that Abbot Laboratories invented TSH - but nowhere can i find the evidence for this. I cannot just say, so and so said they did. If this was a consensus of endocrinologists, I need to know which endocrinologists and in which country and the year. This has to be somewhere. I am a simple seeker after truth. luv - Sheila Hi Sheila The makers of Synthroid being Abbott Laboratories.Chris>> As I have searched and searched and searched and cannot find an answer as to WHO invented the TSH test, I NEED to know if I am correct in thinking that I am having trouble finding articles because there probably are none of significance. Nor can I find if there was a leader of the concept of switching from clinical diagnosis completely to laboratory diagnosis. Am I correct in thinking this was done by CONSENSUS of endocrinologists in 1975 and that there have been NO STUDIES, either before or after. I cannot believe this, so if anybody can prove me wrong and cite medical research and studies I might have missed - I would be delighted....or would I? The implications of finding this was done by consensus ONLY would be appalling considering the thousands of sufferers who are not being given a diagnosis because their TSH is within a range that has been increased this past couple of years, for what reason, we do not know.> > Luv - Sheila>No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.7/1632 - Release Date: 25/08/2008 07:05 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 http://www.thyroidmanager.org/Chapter6a/chapter%206a-text.htm There is a history there, maybe if you wrote to them? I have written to someone too, hopefully we can find out who actually started it out. lotsa luv Dawnx Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B6TDD-4K1F7WF-6 & _user=1\ 0 & _rdoc=1 & _fmt= & _orig=search & _sort=d & view=c & _version=1 & _urlVersion=0 & _userid=10 & \ md5=9cde1e85b777fef33779b507748f6e7d Maybe in here from Abstract, lots of history of tests but I cannot get in without an account. lotsa luv Dawnx Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 TSH Pituitary thyrotrophin (TSH) has always proved difficult to handle, characterize and assay. This hormone is glycoprotein in nature; by analogy with the FSH glycoproteins, 'it' consists of a group of many isohormones; a pituitary contains very small amounts of it; it is difficult to isolate, and laborious to bioassay; apparently it loses some potency soon after isolation, and after being freeze-dried. The first IS, made from bovine pituitaries, was established in 1954. With the 60 introduction of radioimmunoassays in the '60s it rapidly became clear that a standard for human TSH was needed. Enough extracted material was obtained to be ampouled and this became an MRC Research Standard. The use of immunoassays assays of TSH to detect hypothyroidism (which leads to cretinism unless treated soon), has since been an essential routine blood test for all newborn babies; and it also formed one of the most frequent and critical tests used in the differential diagnosis of thyroid disease. This MRC research standard, introduced originally simply for research, thus became an important IRP in 1974. The ECBS then recommended that its replacement should not be contaminated with free alpha subunits common to the other gly http://www.nibsc.ac.uk/documents/Board/HBS.pdf Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Many thanks Dawn. Luv - Sheila TSHPituitary thyrotrophin (TSH) has always proved difficult to handle,characterize and assay. Thishormone is glycoprotein in nature; by analogy with the FSHglycoproteins, 'it' consists of a groupof many isohormones; a pituitary contains very small amounts of it; itis difficult to isolate, andlaborious to bioassay; apparently it loses some potency soon afterisolation, and after beingfreeze-dried. The first IS, made from bovine pituitaries, wasestablished in 1954. With the60introduction of radioimmunoassays in the '60s it rapidly became clearthat a standard for humanTSH was needed. Enough extracted material was obtained to be ampouledand this became anMRC Research Standard. The use of immunoassays assays of TSH to detecthypothyroidism(which leads to cretinism unless treated soon), has since been anessential routine blood test forall newborn babies; and it also formed one of the most frequent andcritical tests used in thedifferential diagnosis of thyroid disease. This MRC research standard,introduced originallysimply for research, thus became an important IRP in 1974. The ECBSthen recommended thatits replacement should not be contaminated with free alpha subunitscommon to the other glyhttp://www.nibsc.ac.uk/documents/Board/HBS.pdfNo virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.9/1634 - Release Date: 25/08/2008 20:48 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Drat - and $31.50 to join.... Luv - Sheila http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B6TDD-4K1F7WF-6 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & view=c & _version=1 & _urlVersion=0 & _userid=10 & md5=9cde1e85b777fef33779b507748f6e7dMaybe in here from Abstract, lots of history of tests but I cannot getin without an account.lotsa luvDawnxNo virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.9/1634 - Release Date: 25/08/2008 20:48 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 I know hon Wish I were still on Athens with Uni, anyone on here with an Athens account which applies to this field at all? They would be able to access it. ANYONE GOT ATHENS PASSWORD? (SORRY FOR SHOUTING) lotsa luv dawnx Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Publications of critical data in expensive access journals makes me think ....they don't want it exposed to ordinary tax-paying mortals.....enables them to see where the tax-burden is being wasted ? Bob wot 'as skeptic as 'is middle name > Drat - and $31.50 to join.... > Luv - Sheila Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Ive got access through the Athens system but the site is down at the moment - I will get it when I can and email it. Gill http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B6TDD-4K1F7WF-6 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & view=c & _version=1 & _urlVersion=0 & _userid=10 & md5=9cde1e85b777fef33779b507748f6e7dMaybe in here from Abstract, lots of history of tests but I cannot getin without an account. Internal Virus Database is out-of-date.Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.6/1192 - Release Date: 21/12/07 13:17 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Hi Sheila Here is a possible link which needs searching as it would have been patented probably in the USA. In my area of the UK a TSH box did not appear on a thyroid function test result until 1988, albeit in my case it was not tested. http://www.freepatentsonline.com/search.html Chris > > > > As I have searched and searched and searched and cannot find an > answer as to WHO invented the TSH test, I NEED to know if I am > correct in thinking that I am having trouble finding articles > because there probably are none of significance. Nor can I find if > there was a leader of the concept of switching from clinical > diagnosis completely to laboratory diagnosis. Am I correct in > thinking this was done by CONSENSUS of endocrinologists in 1975 and > that there have been NO STUDIES, either before or after. I cannot > believe this, so if anybody can prove me wrong and cite medical > research and studies I might have missed - I would be > delighted....or would I? The implications of finding this was done > by consensus ONLY would be appalling considering the thousands of > sufferers who are not being given a diagnosis because their TSH is > within a range that has been increased this past couple of years, > for what reason, we do not know. > > > > Luv - Sheila > > > > > > > No virus found in this incoming message. > Checked by AVG - http://www.avg.com > Version: 8.0.138 / Virus Database: 270.6.7/1632 - Release Date: 25/08/2008 07:05 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Hi Sheila Here's a paper from 1977 which mentions that the kits used were from Abbott Diagnotics, Abbott Laboratories, Illinoi. http://www.clinchem.org/cgi/reprint/23/7/1333.pdf Chris > > > > As I have searched and searched and searched and cannot find an > answer as to WHO invented the TSH test, I NEED to know if I am > correct in thinking that I am having trouble finding articles > because there probably are none of significance. Nor can I find if > there was a leader of the concept of switching from clinical > diagnosis completely to laboratory diagnosis. Am I correct in > thinking this was done by CONSENSUS of endocrinologists in 1975 and > that there have been NO STUDIES, either before or after. I cannot > believe this, so if anybody can prove me wrong and cite medical > research and studies I might have missed - I would be > delighted....or would I? The implications of finding this was done > by consensus ONLY would be appalling considering the thousands of > sufferers who are not being given a diagnosis because their TSH is > within a range that has been increased this past couple of years, > for what reason, we do not know. > > > > Luv - Sheila > > > > > > > No virus found in this incoming message. > Checked by AVG - http://www.avg.com > Version: 8.0.138 / Virus Database: 270.6.7/1632 - Release Date: 25/08/2008 07:05 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Hi Chris That particiular paper is about the assessment of a method for measuring Serum Thyroxine - not Thyroid Stimulating Hormone. It 's not easy finding the evidence we need is it? Luv - Sheila Hi SheilaHere's a paper from 1977 which mentions that the kits used were from Abbott Diagnotics, Abbott Laboratories, Illinoi.http://www.clinchem.org/cgi/reprint/23/7/1333.pdfChris .. No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.9/1635 - Release Date: 26/08/2008 07:29 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Hi Sheila It may be worth emailing Abbott Diagnostics and just asking them if they invented the TSH test and if so when, getting confirmation from the horses mouth so to speak. http://www.synthroid.com/DiagnosisTreatment/TSHTest.cfm I believe it came in with the introduction of T4. Chris - In thyroid treatment , " sheilaturner " <sheilaturner@...> wrote: > > How do you know - I need evidence and what studies did they base this invention on ? Can you poiont me in the right direction, I need to cite this. > > Luv - Sheila > > > > > Hi Sheila > > The TSH test was invented by the makers of Synthroid in 1973. > > Chris > > > > > > As I have searched and searched and searched and cannot find an > answer as to WHO invented the TSH test, I NEED to know if I am > correct in thinking that I am having trouble finding articles > because there probably are none of significance. Nor can I find if > there was a leader of the concept of switching from clinical > diagnosis completely to laboratory diagnosis. : 25/08/2008 07:05 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 26, 2008 Report Share Posted August 26, 2008 Hi Sheila " Serum T4 by CPB (Tetrasorb, Abbott) and T4 RIA charcoal, T: resin uptake (Triosorb, M-125, Abbott), thyroid stimulating hormone (TSH RIA, Abbott), and total T: (T3 RIA, Abbott) were determined by previously established techniques. " Chris > Hi Chris > > That particiular paper is about the assessment of a method for measuring Serum Thyroxine - not Thyroid Stimulating Hormone. It > 's not easy finding the evidence we need is it? > > Luv - Sheila > > > Hi Sheila > > Here's a paper from 1977 which mentions that the kits used were from > Abbott Diagnotics, Abbott Laboratories, Illinoi. > > http://www.clinchem.org/cgi/reprint/23/7/1333.pdf > > Chris > > Recent Activity > a.. 15New Members > b.. 19New Files > Visit Your Group > Health > Heartburn or Worse > > What symptoms > > are most serious? > > Meditation and > Lovingkindness > > A Group > > to share and learn. > > Find helpful tips > for Moderators > > on the > > Groups team blog. > . > > No virus found in this incoming message. > Checked by AVG - http://www.avg.com > Version: 8.0.138 / Virus Database: 270.6.9/1635 - Release Date: 26/08/2008 07:29 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 27, 2008 Report Share Posted August 27, 2008 Sheila - have a look at the link again, its working now but the Athens log in isnt, it does allow guest access but you may not be able to get the pdf - I'll keep checking back. Gill WHOOPEEE! I knew you would come in useful again Gill - there you go, there IS a reason for us being here. *grin* Luv - Sheila Ive got access through the Athens system but the site is down at the moment - I will get it when I can and email it. Gill http://www.sciencedirect.com/science?_ob=ArticleURL & _udi=B6TDD-4K1F7WF-6 & _user=10 & _rdoc=1 & _fmt= & _orig=search & _sort=d & view=c & _version=1 & _urlVersion=0 & _userid=10 & md5=9cde1e85b777fef33779b507748f6e7dMaybe in here from Abstract, lots of history of tests but I cannot getin without an account. Internal Virus Database is out-of-date.Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.6/1192 - Release Date: 21/12/07 13:17 No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.9/1635 - Release Date: 26/08/2008 07:29 Internal Virus Database is out-of-date.Checked by AVG Free Edition. Version: 7.5.516 / Virus Database: 269.17.6/1192 - Release Date: 21/12/07 13:17 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 9, 2008 Report Share Posted September 9, 2008 Hi Sheila, I understood that Toft had a hand in it? thyroid treatment From: sheilaturner@...Date: Mon, 25 Aug 2008 21:43:23 +0100Subject: Re: Re: WHO KNOWS? Hi Chris I have heard on other forums members saying that Abbot Laboratories invented TSH - but nowhere can i find the evidence for this. I cannot just say, so and so said they did. If this was a consensus of endocrinologists, I need to know which endocrinologists and in which country and the year. This has to be somewhere. I am a simple seeker after truth. luv - Sheila Hi Sheila The makers of Synthroid being Abbott Laboratories.Chris>> As I have searched and searched and searched and cannot find an answer as to WHO invented the TSH test, I NEED to know if I am correct in thinking that I am having trouble finding articles because there probably are none of significance. Nor can I find if there was a leader of the concept of switching from clinical diagnosis completely to laboratory diagnosis. Am I correct in thinking this was done by CONSENSUS of endocrinologists in 1975 and that there have been NO STUDIES, either before or after. I cannot believe this, so if anybody can prove me wrong and cite medical research and studies I might have missed - I would be delighted....or would I? The implications of finding this was done by consensus ONLY would be appalling considering the thousands of sufferers who are not being given a diagnosis because their TSH is within a range that has been increased this past couple of years, for what reason, we do not know.> > Luv - Sheila>No virus found in this incoming message. Checked by AVG - http://www.avg.com Version: 8.0.138 / Virus Database: 270.6.7/1632 - Release Date: 25/08/2008 07:05 Get Hotmail on your mobile from Vodafone Try it Now Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 9, 2008 Report Share Posted September 9, 2008 http://www.sciencedaily.com/releases/2007/07/070725174453.htm This also might be a start - looking for the patent but I wouldn't know what it would be called, not do I do roughly the date when it was first invented. Maybe , Bob or one of the others might be able to help there. I presume it was patented. http://www.patentstorm.us/patents/6844162/description.html http://www.patentstorm.us/patents/6537760.html I am sorry I cannot read these things as my eyes are so sore so do not know exactly what they say and if they will help. Lilian Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 9, 2008 Report Share Posted September 9, 2008 Would the information you require be in here somewhere? http://www.wipo.int/pctdb/en/wo.jsp?IA=US1990005066 & DISPLAY=DESC http://patents.ic.gc.ca/cipo/cpd/en/patent/1280691/summary.html http://www.zampbioworld.org/bionews/index.php/2007/07/29/2542 Lilian Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 9, 2008 Report Share Posted September 9, 2008 Just one more. http://www.freepatentsonline.com/EP0212522.html Lilian Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 10, 2008 Report Share Posted September 10, 2008 I heard that too, but need the facts. Luv - Sheila Hi Sheila, I understood that Toft had a hand in it? .. No virus found in this incoming message.Checked by AVG - http://www.avg.com Version: 8.0.169 / Virus Database: 270.6.19/1663 - Release Date: 09/09/2008 19:04 Quote Link to comment Share on other sites More sharing options...
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