Fw: [hypothyroidism] Iodine

[Guest guest]

This was on another list from a guy who is a Physics professor! and on

$inthroid!

Can someone respond to this?

Gracia

> Gracia,

>

> You wrote:

>>

>> Chuck you are misinformed on this one!

>> http://www.optimox.com

>

> Thank you, I am much better informed now that I have read the

> advertisement.

>

> I went to the link marked " Research " from the Optimox page to also be

> better informed about the quality of evidence supporting these ads and

> found that every single article backing the gobs of expensive iodine

> supplements are good for you thesis was published in a single journal,

> _The Original Internist_. Every other article cited in footnotes under

> the Iodine Products section also came from this journal. The other five

> were articles that set RDAs and verified things unrelated to the

> supplements.

>

> This is the continuation of a journal named _The Internist_, which was

> started in 1994 by a chiropractor named Jack Kessinger and his wife.

> However, instead of " research, " the stated purpose of this journal is to

> be " educational and informative, " designed to " enhance enthusiasm and

> stimulate communication concerning the ever-expanding opportunities for

> chiropractic. " To paraphrase the rest of its description, the articles

> are testimonials developed from family practice in chiropractic. They

> are not peer reviewed research.

>

> If you compare the RDA of iodine (as potassium iodide, 0.15 mg) with the

> amount in a levothyroxine supplement (four atoms of iodine per

> molecule), you can see that full replacement thyroid meds plus your

> daily intake will more than meet the RDA, as I stated.

>

> Here is what the National Research Council has to say about iodine

> supplements in _Recommended Dietary Allowances_, 10th ed. Washington,

> D.C.: National Academy Press, 1989.

>

> [begin quote]

>

> Too much or too little iodine intake results in a wide spectrum of

> disorders that are addressed by adjusting iodine intake. Too much iodine

> can result in toxicity.

>

> Excess iodine is typically excreted, and output can be measured in the

> urine. Regular excessive iodine intake is needed for toxicity. Excess

> iodine, when used as a supplement or in drug therapy, may reduce thyroid

> function. Although more commonly associated with iodine deficiency,

> goiter can also result from too much iodine due to thyroid

> hyperactivity. Additionally, high amounts of iodine from sources such as

> overuse of iodized salt, vitamins, cough medications, kelp tablets, or

> from medical testing can cause effects including rapid pulse,

> nervousness, headaches, fatigue, a brassy taste in the mouth, excessive

> salivation, gastric irritation, and hypothyroidism. Acne can appear or

> become worse. Some iodine-sensitive individuals may have an allergic

> reaction to iodine, often a skin rash. A physician may recommend that

> high iodine foods be removed from the diet of those who are

> iodine-sensitive. Similar side effects have also been observed in some

> women participating in studies on iodine and diagnosed FBD. Radioactive

> iodine has been implicated in producing thyroid dysfunction and thyroid

> cancer.

>

> Other Resources:

>

> The Merck Manual of Diagnosis and Therapy. 17th ed. Edited by Mark H.

> Beers and Berkow. Whitehouse Station, N.J.: Merck Research

> Laboratories, 1999.

> ORGANIZATIONS

>

> U.S. Fund for UNICEF. 333 East 38th Street NY, NY 10016.

> http://www.unicefusa.org/issues99/sep99/learn.html.web

> master@....

>

> World Health Organization (WHO). Avenue Appia 20 1211 Geneva 27,

> Switzerland. (+00–41–22)791–21–11. Fax: (+00–41–22)791–311.

> http://www.who.int/inf-fs/en/fact 121.html. info@....

>

> International Council for Control of Iodine deficiency Disorders

> (ICCIDD). Prof. Jack Ling. Director, ICEC. 1501 Canal Street, Suite

> 1304, New Orleans, LA 70112. (504)584–3542 Fax: (504)585–4090.

> ICEC@....

>

> http://www.people.virginia.edu/~jtd/iccidd/.

>

> [end quote]

>

> Here is another abstract from PubMed: J Am Diet Assoc. 1990

> Nov;90(11):1571-81. " A review of iodine toxicity reports. " Pennington

> JA, Division of Nutrition, Food and Drug Administration, Washington, DC

> 20204.

>

> This article summarizes case reports, population studies, and

> experimental studies from the literature concerning adverse effects of

> exposure to iodine from the mid-1880s to 1988. Exposure to excessive

> iodine through foods, dietary supplements, topical medications, and/or

> iodinated contrast media has resulted in thyroiditis, goiter,

> hypothyroidism, hyperthyroidism, sensitivity reactions, or acute

> responses for some individuals. Reports of maternal iodine exposure

> during pregnancy or lactation affecting newborn or nursing infants are

> cited. Susceptibility to excess iodine is discussed as well as the

> relationship between dose and response. It is concluded that some

> individuals can tolerate very high levels of iodine with no apparent

> side effects and that iodine intakes less than or equal to 1.000 mg/day

> are probably safe for the majority of the population, but may cause

> adverse effects in some individuals. Determination of maximum tolerable

> levels of iodine intake will require human experimental studies at

> levels between 0.150 and 1.000 mg/day for normal subjects, subjects with

> autonomous thyroid tissue, and iodine-sensitive subjects.

>

> Here is another from Exp Mol Pathol. 1986 Jun;44(3):259-71.

> " Direct toxic effect of iodide in excess on iodine-deficient thyroid

> glands: epithelial necrosis and inflammation associated with lipofuscin

> accumulation. " Mahmoud I, Colin I, Many MC, Denef JF.

>

> Involution of thyroid hyperplasia (induced by a low iodine diet and

> a goitrogen, propylthiouracil, PTU) was obtained in mice by

> administering a high or a moderate dose of iodide (HID or MID,

> respectively). In HID involuting glands, vasoconstriction was observed

> after 12 hr whereas necrosis and inflammation were very abundant as

> early as after 6 hr and maximal after 48 hr. They were not prevented by

> papaverine by which vasoconstriction was inhibited, but were inhibited

> by the continuation of PTU by which iodide oxidation and organification

> were inhibited. Lipofuscin inclusions in thyroid and inflammatory cells

> were always associated with necrosis. On the contrary, when involution

> was induced by MID or by HID + triiodothyronine (T3), or by T3 alone,

> neither necrosis nor inflammation occurred and apoptosis was the only

> mode of cell deletion. No lipofuscin inclusion occurred. Our results

> demonstrate that iodide in excess, after being oxidized or organified,

> is directly toxic for iodine-deficient thyroid cells. The presence of

> lipofuscin suggests that its toxicity is mediated by lipid peroxidation,

> a consequence of production of free radicals in excess.

>

> More sources at:

> http://www.food.gov.uk/multimedia/pdfs/evm_iodine.pdf

>

> So, you can choose between the National Research Council or the Original

> Internist. Sorry I was so misinformed.

>

> Chuck

>

>

>