Wt loss improves DM 2

[Guest guest]

Lots of studies like this showing that weight loss improves Diabetes 2 - and

certainly DM 1 as well. As usual, no need to drag through the research and

methodology - just go to the " conslusions " at the end for the outcomes.

Studies are the basis of Allegan's heavy marketing of the Band to people much

less overweight than any of us had to be to qualify for surgery.

The line at which the RISKS of surgery (death, surgical errors causing

problems/disability, longterm problems/complications, etc) outweight the

BENEFITS is getting less and less clear.

With the serious effort required to do well with the Band, as well as the clear

risks, I hope unscrupulous surgeons are not going to be putting bands in people

needing only to lose 30-40 #. Time will tell.

Sandy

______________________________________________________________

Benefits of modest weight loss in improving cardiovascular risk factors in

overweight and obese individuals with type 2 diabetes.

Diabetes Care. 2011; 34(7):1481-6 (ISSN: 1935-5548)

Wing RR; Lang W; Wadden TA; Safford M; Knowler WC; Bertoni AG; Hill JO; Brancati

FL; s A; Wagenknecht L;

Department of Psychiatry and Human Behavior, Brown Medical School, The Miriam

Hospital, Providence, Rhode Island, USA. rwing@...

OBJECTIVE: Overweight and obese individuals are encouraged to lose 5-10% of

their body weight to improve cardiovascular disease (CVD) risk, but data

supporting this recommendation are limited, particularly for individuals with

type 2 diabetes.

RESEARCH DESIGN AND METHODS: We conducted an observational analysis of

participants in the Look AHEAD (Action For Health in Diabetes) study (n=5,145,

40.5% male, 37% from ethnic/racial minorities) and examined the association

between the magnitude of weight loss and changes in CVD risk factors at 1 year

and the odds of meeting predefined criteria for clinically significant

improvements in risk factors in individuals with type 2 diabetes.

RESULTS: The magnitude of weight loss at 1 year was strongly (P<0.0001)

associated with improvements in glycemia, blood pressure, tryiglycerides, and

HDL cholesterol but not with LDL cholesterol (P=0.79). Compared with

weight-stable participants, those who lost 5 to <10% ([means±SD] 7.25±2.1 kg) of

their body weight had increased odds of achieving a 0.5% point reduction in

HbA1c (odds ratio 3.52 [95% CI 2.81-4.40]), a 5-mmHg decrease in diastolic blood

pressure (1.48 [1.20-1.82]), a 5-mmHg decrease in systolic blood pressure (1.56

[1.27-1.91]), a 5 mg/dL increase in HDL cholesterol (1.69 [1.37-2.07]), and a 40

mg/dL decrease in triglycerides (2.20 [1.71-2.83]). The odds of clinically

significant improvements in most risk factors were even greater in those who

lost 10-15% of their body weight.

**** CONCLUSIONS: Modest weight losses of 5 to <10% were associated with

significant improvements in CVD risk factors at 1 year, but larger weight losses

had greater benefits.