Guest guest Posted November 2, 2006 Report Share Posted November 2, 2006 Oh excellent!!! Thank you so much for finding and posting this. Great information! --- jtb14789 <jtb14789@...> wrote: > I found these two links very interesting. I haven't > come across this > on the board yet. Sorry if it's a repeat. > > The first involves finding antibodies, not only to > the thyroid gland > itself, but to the sodium-iodine transport system > (NIS). The second > involves the importance of sufficient selenium when > supplementing > with iodine. ________________________________________________________________________________\ ____ Get your email and see which of your friends are online - Right on the New .com (http://www./preview) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 2, 2006 Report Share Posted November 2, 2006 I have Hashi since ~1990 and am aggravated by both too-high iodine and too-high selenium, with visible thyroid inflammation and rosacea exacerbation resulting from either or both. Even 25 mcg selenium is a problem for me. I get some iodine in foods, plus whatever iodine is in 120 mg Armour. Anything that makes the thyroid " produce " seems to get attacked by the antibodies. This might happen with 1-5% of hashi persons? wild guess. Brazil nuts, fish (especially salmon), spirulina and other blue green algaes have high selenium. Some say that the high selenium in fish offsets the mercury - dunno, just mention it for anyone interested in mercury. Antibodies to the NIS is interesting. I want to track down a test for that, just for curiosity. Carol Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 3, 2006 Report Share Posted November 3, 2006 This is fascinating but also confusing, how should I supplement if I have been diagnosed with hashimoto? Also, what is the best way to supplement iodine? I have IODORAL but I am a little scared to take it now. Thank you. > > I found these two links very interesting. I haven't come across this > on the board yet. Sorry if it's a repeat. > > The first involves finding antibodies, not only to the thyroid gland > itself, but to the sodium-iodine transport system (NIS). The second > involves the importance of sufficient selenium when supplementing > with iodine. > > http://www.thyroidmanager.org/chapter8/8__iodide_metabolism.htm > " ...Many patients with Hashimoto's thyroiditis do not respond to > injected TSH with the expected increase in RAIU or release of > hormone from the gland(81). These findings probably mean that the > gland is partially destroyed by the autoimmune attack and is unable > to augment iodine metabolism further. Further, the thyroid gland of > the patient with Hashimoto's disease does not organify normally (82) > (Fig. 8-4). Administration of 400 mg potassium perchlorate 1 hour > after giving a tracer iodide releases 20 - 60% of the glandular > radioactivity. Also, a fraction of the iodinated compounds in the > serum of patients with Hashimoto's thyroiditis is not soluble in > butanol, as are the thyroid hormones, but is an abnormal peptide- > linked iodinated component. This low-weight iodoprotein is probably > serum albumin that has been iodinated in the thyroid gland. A > similar iodoprotein is also found in several other kinds of thyroid > disease, including carcinoma, Graves' disease, and one form of > goitrous cretinism. It may be formed as part of the hyperplastic > response. TG is also detectable in their serum. > > Iodide is actively transported from blood to thyrocytes and recently > the sodium / iodide symporter (NIS) has been cloned. Antibodies > against NIS were found in autoimmune thyroid disease(83). This > antibody has an inhibitory activity on iodide transport and may > modulate the thyroid function in Hashimoto's thyroiditis. More > recent studies reported rather low prevalence (less than 10%) of > anti-NIS antibodies in Hashimoto's disease and clinical relevance is > still unknown(84),(85)... " > > http://www.ithyroid.com/iodine.htm > " ...This result is made worse by another phenomenon which hasn't > been thoroughly studied: a selenium deficiency causes an iodine > deficiency to get worse. This may be a protective adaptation by the > body to limit the damage caused to the thyroid when selenium is > deficient and iodine is adequate. Let's examine this part of the > interaction. > > We've all heard that many doctors tell hypo patients, especially > those with Hashimoto's thyroiditis, not to take iodine because it > can aggravate their condition. The reason seems to be that selenium > protects the thyroid gland from oxidative damage and this damage can > increase significantly if iodine is supplemented. Taking iodine will > increase thyroid hormone production and the production of H2O2 which > damages the thyroidal cells. The lack of selenium prevents GPX from > being able to protect the cells from this oxidative damage. While I > doubt if most doctors realize why iodine should be restricted (it > certainly seemed counter-intuitive to me at first), they have > learned through experience that iodine can increase the thyroid > damage in Hashimoto's. The information that selenium should be > supplemented along with iodine is so new that most of them are > unaware of it. > > Here's what we have: Studies have shown that if iodine is low, > selenium must also be kept low to prevent the hypothyroidism from > becoming worse (from increased DI-I and T4 depletion, as explained > above.) So if both minerals are low, then the person is hypo and > gets a goiter, but the damage to the thyroid is kept to a minimum. > More severe problems happen when either selenium or iodine is high > and the other is low. If selenium is high and iodine low, then T4 to > T3 to T2 conversion is accelerated without T4 being replenished, > leading to a worsening of the hypoT. If iodine is high and selenium > is low, then H2O2 is not degraded by GPX. Since H2O2 drives the > thyroid hormone production, then the thyroid over-produces thyroid > hormone (Grave's hyperthyroidism), the thyroid is damaged from the > oxidation by the H2O2, and the end result is that the damaged > thyroid ultimately decreases activity and hypothyroidism results > (Hashimoto's thyroiditis). This could explain the observed > progression of Grave's to Hashimoto's. > > If a selenium deficiency causes an iodine deficiency, leaving you > both selenium and iodine deficient, and supplementing with either > selenium or iodine causes severe problems, then the only solution is > to supplement both selenium and iodine simultaneously and gradually. > Even then you could experience an immediate boost (from increased > conversion of T4 to T3) with a subsequent letdown (lack of T4 > production because of insufficient iodine or other necessary > nutrient). You have to be prepared to ride out the tough times and > continue increasing the selenium and iodine until those two > deficiencies are corrected and the respective metabolic pathways are > back working properly. > > Everything that I've read about selenium indicates that it is > absolutely essential for proper functioning of the thyroid. A > deficiency of selenium may lead to either hyperthyroidism or > hypothyroidism. I've always wondered if high intake of selenium can > lead to hyperthyroidism and finally found someone who did the > experiment. They found that a high intake of selenium will not > increase T4 production and lead to hyperthyroidism. > > If a person has hyperT, then it looks like taking selenium without > iodine will result in a decrease in production of T4 (although there > may be an initial transient increase in T4 to T3 conversion and > hence higher T3). I would suggest to start with a small amount of > selenium methionine (about 50 mcg) and gradually increase it. I > cannot see any way that thyroid function can be normalized without > selenium. > > For hypos the important message is that a selenium deficiency may > cause an iodine deficiency, so that even though you are taking > iodine you may not be assimilating it unless selenium is also being > taken. This would explain how people can have iodine deficiencies > even though salt and many foods have iodine added. Supplement with > both iodine and selenium. I would recommend starting with 100 mcg of > selenium and one kelp tablet and gradually work up to 400-600 mcg of > selenium and 2-4 tablets of kelp.... " > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2008 Report Share Posted April 18, 2008 Hi All, New here and trying to read up on the role of iodine in hypothyroid treatment. Does anyone have any links or info on iodine & Hashimoto's? Also, is there a home test one can do for iodine? TIA! Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 18, 2008 Report Share Posted April 18, 2008 The test for iodine (where you can order) is in the files and it should have been part of the frequently asked questions e-mail you got when joining. Go to www.iodine4health.com for more info on iodine and the thyroid. Steph Iodine & Hashimoto's > Hi All, > > New here and trying to read up on the role of iodine in hypothyroid > treatment. > > Does anyone have any links or info on iodine & Hashimoto's? > > Also, is there a home test one can do for iodine? > > TIA! > > > ------------------------------------ > > > > > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.