Re: Invitation to have an entry in the MHRA Database of Health NGOs

[Guest guest]

What to make of that then? I am always suspicious of things like this. Hope it is a step in the right direction.Be careful Sheila Carol X Invitation to have an entry in the MHRA Database of Health NGOs

Well - I am not sure whether it is the article today that has prompted this invitation, but I am certainly delighted and will take this up.

Luv - Sheila

____________ _________ ________

Dear Sheila The Medicines and Healthcare products Regulatory Agency (MHRA) is inviting all national patient organisations, and other health-related NGOs, to be entered onto its new Database of Health NGOs. As you may know, the MHRA is the government agency responsible for ensuring that medicines and medical devices (or equipment) work, and are acceptably safe. For further information, see the footnote, below. The MHRA Database of Health NGOs is being set up in early 2008 to allow patient organisations and health NGOs to assist the MHRA in the conduct of its important public work. We believe that your organisation may benefit from being involved in the work of the MHRA: Firstly, your organisation may wish to have the opportunity to convey to the MHRA the views of your members (or the people you represent) on relevant issues and themes related to medicines and devices. Secondly, your organisation can join many of your peer groups in helping protect patients from problems that may arise from medicines/devices (such as from counterfeiting, contamination, or poor manufacture) . Sometimes, the continued use of such products can have serious consequences, and the MHRA needs to alert as many appropriate people about them as quickly as possible. By passing on to your members crucial MHRA safety information, or new facts about the effects on patients of medicines/devices, you will be doing a service to yourselves and your members and constituency. Even if you have no facilities for disseminating information, you might want to hear of topical safety problems before your members or constituents contact you about them. Please rest assured that the MHRA does not intend to swamp you with information or requests. If there is no urgent safety information for your members or constituency, you will not get any. The MHRA will only ask for views about relatively important issues, and will only approach organisations that it believes may have an interest in such issues. If you would like your organisation to be entered onto the Database, you need only complete a short entry form, below (which asks for overview information about your organisation, plus contact details). Your organisation¢ s details will remain confidential, and will be used by the MHRA solely for the purposes described in this email. TO HAVE AN ENTRY IN THE MHRA DATABASE OF HEALTH NGOs, PLEASE CLICK ON THE FOLLOWING LINK: (I have removed this link).

We do hope that your organisation will welcome this opportunity to be involved with the Medicines and Healthcare products Regulatory Agency. The creation of the MHRA Database of Health NGO is being initially administered by PatientView, an independent researcher and publisher. In early 2008, PatientView will send out an email acknowledging receipt of the entry form and entry onto the Database. The MHRA Database of Health NGOs will become activated shortly after that. If you have any further questions about the Database, please feel free to email Louise Oatham , Administrator [MHRA Health NGO Database], PatientView, on info@patient- view.com . Kind regards, Simon Gregor Director of Communications, Medicines and Healthcare products Regulatory Agency 10-2 Market Towers 1 Nine Elms Lane London SW8 5NQ

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[Guest guest]

Well I think the first campaign might be to notify of the ineffectivity

of synthetic thyroxine compounds that just don't work for a huge number

of people!!

> DearWell - I am not sure whether it is the article today that has

prompted this invitation, but I am certainly delighted and will take

this up.

>

>

[Guest guest]

Right on Glynis - that certainly will be our first. I can't believe I was sent this invitation. They wanted me to nominate a person to go to their meetings (if we were picked because of our subject matter) so I have nominated Lee who has agreed. The MHRA pay all expenses. I knew this article would be the start of good things to come.

Luv - Sheila

Well I think the first campaign might be to notify of the ineffectivity of synthetic thyroxine compounds that just don't work for a huge number of people!!> DearWell - I am not sure whether it is the article today that has prompted this invitation, but I am certainly delighted and will take this up.> >

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[Guest guest]

-Hi Sheila

Maybe this will be of some help in the campaign:

Endocrine Abstracts 3 S40

T3/T4 combination therapy

AD Toft

Endocrine Clinic, Royal Infirmary, Edinburgh, UK.

---------------------------------------------------------------------

-----------

The first treatment for hypothyroidism introduced at the end of the

19th century was animal thyroid extract which contained both T3and

T4. Because of variable potency it was widely replaced by synthetic

T4 from the 1960s in high doses of 200-400 ug daily to compensate

for the lack of T3. The development of TSH assays showed that a dose

of T4 of 100-150 ug daily was usually adequate to restore serum TSH

to normal. Because a suppressed serum TSH has been shown to be a

risk factor for osteoporosis, atrial fibrillation, and most recently

for excess cardiovascular mortality, there is a consensus that the

correct treatment of hypothyroidism is a dose of thyroxine which

restores euthyroidism and maintains both T4 and TSH in their

respective reference ranges. However, a significant minority of

patients only achieve the desired sense of well-being if serum TSH

is suppressed. Furthermore, patients rendered hypothyroid following

treatment of thyrotoxicosis and taking a dose of T4 which maintains

a normal TSH, gain more weight than those who do not become

hypothyroid. Studies in hypothyroid rats suggest that it is only

possible to restore universal tissue euthyroidism using a

combination of T3and T4. In patients in whom long-term T4 therapy

was substituted by the equivalent combination of T3 and T4 scored

better in a variety of neuropsychological tests. It would appear

that the treatment of hypothyroidism is about to come full circle.

---------------------------------------------------------------------

-----------

Endocrine Abstracts 3 S40

-- In thyroid treatment , " sheilaturner "

<sheilaturner@...> wrote:

>

> Right on Glynis - that certainly will be our first. I can't

believe I was sent this invitation. They wanted me to nominate a

person to go to their meetings (if we were picked because of our

subject matter) so I have nominated Lee who has agreed. The MHRA pay

all expenses. I knew this article would be the start of good things

to come.

>

> Luv - Sheila

>

>

> Well I think the first campaign might be to notify of the

ineffectivity

> of synthetic thyroxine compounds that just don't work for a huge

number

> of people!!

>

> > DearWell - I am not sure whether it is the article today that

has

> prompted this invitation, but I am certainly delighted and will

take

> this up.

> >

> >

>

>

>

>

>

>

> -------------------------------------------------------------------

-----------

>

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release

Date: 06/01/2008 11:57

>

[Guest guest]

Many thanks for this Chris. I now have a massive collection of references for the BTA. Hopefully, we will have these on our website VERY shortly.

Luv - Sheila

Re: Invitation to have an entry in the MHRA Database of Health NGOs

-Hi SheilaMaybe this will be of some help in the campaign:Endocrine Abstracts 3 S40 T3/T4 combination therapyAD Toft Endocrine Clinic, Royal Infirmary, Edinburgh, UK.---------------------------------------------------------------------The first treatment for hypothyroidism introduced at the end of the 19th century was animal thyroid extract which contained both T3and T4. Because of variable potency it was widely replaced by synthetic T4 from the 1960s in high doses of 200-400 ug daily to compensate for the lack of T3. The development of TSH assays showed that a dose of T4 of 100-150 ug daily was usually adequate to restore serum TSH to normal. Because a suppressed serum TSH has been shown to be a risk factor for osteoporosis, atrial fibrillation, and most recently for excess cardiovascular mortality, there is a consensus that the correct treatment of hypothyroidism is a dose of thyroxine which restores euthyroidism and maintains both T4 and TSH in their respective reference ranges. However, a significant minority of patients only achieve the desired sense of well-being if serum TSH is suppressed. Furthermore, patients rendered hypothyroid following treatment of thyrotoxicosis and taking a dose of T4 which maintains a normal TSH, gain more weight than those who do not become hypothyroid. Studies in hypothyroid rats suggest that it is only possible to restore universal tissue euthyroidism using a combination of T3and T4. In patients in whom long-term T4 therapy was substituted by the equivalent combination of T3 and T4 scored better in a variety of neuropsychological tests. It would appear that the treatment of hypothyroidism is about to come full circle.---------------------------------------------------------------------Endocrine Abstracts 3 S40 -- In thyroid treatment , "sheilaturner" <sheilaturner@...> wrote:>> Right on Glynis - that certainly will be our first. I can't believe I was sent this invitation. They wanted me to nominate a person to go to their meetings (if we were picked because of our subject matter) so I have nominated Lee who has agreed. The MHRA pay all expenses. I knew this article would be the start of good things to come.> > Luv - Sheila> > > Well I think the first campaign might be to notify of the ineffectivity > of synthetic thyroxine compounds that just don't work for a huge number > of people!!> > > DearWell - I am not sure whether it is the article today that has > prompted this invitation, but I am certainly delighted and will take > this up.> > > >> > > > > > > ---------------------------------------------------------------------> > > No virus found in this incoming message.> Checked by AVG Free Edition. > Version: 7.5.516 / Virus Database: 269.17.13/1211 - Release Date: 06/01/2008 11:57>

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[Guest guest]

Good, with all the evidence you have maybe they will start to realise

that Armour is more effective and safer.

This year (2008)is auspicious. If you add up all the numbers 2+8 =10

1+0 =1, in numerology the number one means 'new beginnings'.

> Right on Glynis - that certainly will be our first. I can't believe I

was sent this invitation. They wanted me to nominate a person to go to

their meetings (if we were picked because of our subject matter) so I

have nominated Lee who has agreed. The MHRA pay all expenses. I knew

this article would be the start of good things to come.

>