radiation complications in neuropathy - to Martha

[Guest guest]

Martha, found this too: all the articles I searched just mention

neuropathy in general. I did not find any that were CMT specific. ~

Gretchen

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1: Mayo Clin Proc 2001 Aug;76(8):849-52

Arteritis and brachial plexus neuropathy as delayed complications of

radiation therapy.

Rubin DI, Schomberg PJ, Shepherd RF, Panneton JM.

Division of Clinical Neurophysiology, Mayo Clinic, Rochester, Minn

55905, USA. rubin.devon@...

Radiation-induced arteritis of large vessels and brachial plexus

neuropathy are

uncommon delayed complications of local radiation therapy. We describe a

66-year-old woman with right arm discomfort, weakness, and acrocyanosis

that developed 21 years after local radiation for breast adenocarcinoma.

Arteriography revealed arteritis, with ulcerated plaque formation at the

subclavian-axillary artery junction, consistent with radiation-induced

disease, and diffuse irregularity of the axillary artery.

Electromyography showed a chronic brachial plexopathy. The patient's

acrocyanosis, thought to be due to digital embolization from her

vascular disease, improved with antiplatelet therapy. The concurrent

combination of radiation-induced arteritis and

brachial plexopathy is uncommon but should be considered in patients

presenting with upper extremity pain or weakness after radiation

therapy.