Agriculture Products as Xenobiotics

[Guest guest]

Dear Dr. Bharat Gajjarji:

Please don't be disheartened from a comparatively lesser participation of Netrum members in your current topic. I think we have had a very healthy, short but crisp discussion on agricultural products as xenobiotics. If your previous discussion on Modern medicines in drinking water was a block buster, this one was still a hit, no need to express any regrets whatsoever sir. Tommorrow is the final day of this discussion. We can still utilize it in consolidating our discussion on the direct health impact of these products on human beings. No player can be expected to score a century in every match so is the case with netrum discussions. Please read all my comments in a lighter vein and not seriously.

With kind regards

Dr. Geer M. Ishaq

Sr. Lecturer

Dept. of Pharmaceutical Sciences

University of Kashmir

Srinagar-190006 (J & K)

Ph: 9419970971, 9906673100

E-mail: ishaq@...

Website: http://ishaqgeer.googlepages.com

Agriculture Products as Xenobiotics

Dear friends,Tomorrow is the last day of discussion.Somehow, I am not so happy with the discussion going on.Either members are not having interest or failure on my part to generate interest amongst members.Accepting second possibility and considering lacuna on my part, I apologize the members.DR. BHARAT GAJJAR ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY, PRAMUKHSWAMI MEDICAL COLLEGE, KARAMSAD-388325. DIST.-ANAND (GUJARAT) INDIA. MOBILE- 09428153344.

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[Guest guest]

Dear Dr. Geer,

Thank you for your consolating words.

No doubt, we have discussed the topic thouroughly. We have tried to

touch all the aspects. For this, I am thankful to all participants

particularly Dr. Anupama and you.

Today is the last day.

Let us discuss health hazards of agriculture (occupational hazards) and precautions to prevent/minimize the hazards. DR. BHARAT GAJJAR ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY, PRAMUKHSWAMI MEDICAL COLLEGE, KARAMSAD-388325. DIST.-ANAND (GUJARAT) INDIA. MOBILE- 09428153344.From: Geer M. Ishaq <ishaqgeer@...>Subject: Re: Agriculture Products as XenobioticsTo:

netrum Date: Thursday, May 15, 2008, 10:14 PM

Dear Dr. Bharat Gajjarji:

Please don't be disheartened from a comparatively lesser

participation of Netrum members in your current topic. I think we have

had a very healthy, short but crisp discussion on agricultural products

as xenobiotics. If your previous discussion on Modern medicines in

drinking water was a block buster, this one was still a hit, no need to

express any regrets whatsoever sir. Tommorrow is the final day of this

discussion. We can still utilize it in consolidating our discussion on

the direct health impact of these products on human beings. No player

can be expected to score a century in every match so is the case with

netrum discussions. Please read all my comments in a lighter vein

and not seriously.

With kind regards

Dr. Geer M. Ishaq

Sr. Lecturer

Dept. of Pharmaceutical Sciences

University of Kashmir

Srinagar-190006 (J & K)

Ph: 9419970971, 9906673100

E-mail: ishaq@kashmiruniver sity.ac.in

Website: http://ishaqgeer. googlepages. com

Agriculture Products as Xenobiotics

Dear friends,Tomorrow is the last day of discussion.Somehow,

I am not so happy with the discussion going on.Either members are not

having interest or failure on my part to generate interest amongst

members.Accepting second possibility and considering lacuna on my part,

I apologize the members.DR. BHARAT GAJJAR ASSOCIATE PROFESSOR,

DEPARTMENT OF PHARMACOLOGY, PRAMUKHSWAMI MEDICAL COLLEGE,

KARAMSAD-388325. DIST.-ANAND (GUJARAT) INDIA. MOBILE- 09428153344.

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[Guest guest]

Dear Dr. Bharat Gajjar:

My research area during my post-graduation has been genotoxicity/mutagenicity testing. I have worked on lead nitirate which is an environmental pollutant, apart from cyclophosphamide. It should also be noted that several commonly used pesticides are derivatives of N-methylcarbamic acid and could conceivably give rise to the corresponding N-nitrosocompounds by interaction with nitrous acid in the environment or in vivo. Nitroso compounds are known mutagens/carcinogens. Most of the pesticides and other such agricultural products like insecticides, fungicides, herbicides, fumigants, acaricides, seed sterilants, soil nematocides, growth inhibitors,

growth regulators, and chemosterilants etc have been tested for mutagenicity using in-vitro methods like Salmonella mutagenicity testing and in-vivo methods like mouse bone-marrow micronucleus and chromosome aberration tests have been found to be highly genotoxic which is a direct indicator of their implied carcinogenicity. Apart from the dangers of their acute and chronic poisoning, the possible mutagenic effects of such contaminations could threaten the genetic health of future generations. A number of these agents are used in considerable amounts in such forms as granular formulations, dusts, powders, sprays, foams, and aerosols, and hence man can be exposed to these agents via handling of these agents per se, re-entry into a treated area, through ecological distribution, or via consumption of toxicant residues in food. There are a lot of studies on mutagenicity testing of pesticides and other agricultural products mentioned above. Thus they pose a direct occupational hazard to our farmer community who are thereby exposed to a number of hereditary and degenerative disorders like atherosclerosis, cancer etc.

Dr. Geer M. Ishaq

Sr. Lecturer

Dept. of Pharmaceutical Sciences

University of Kashmir

Srinagar-190006 (J & K)

Ph: 9419970971, 9906673100

E-mail: ishaq@...

Website: http://ishaqgeer.googlepages.com

Agriculture Products as Xenobiotics

Dear friends,Tomorrow is the last day of discussion.Somehow, I am not so happy with the discussion going on.Either members are not having interest or failure on my part to generate interest amongst members.Accepting second possibility and considering lacuna on my part, I apologize the members.DR. BHARAT GAJJAR ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY, PRAMUKHSWAMI MEDICAL COLLEGE, KARAMSAD-388325. DIST.-ANAND (GUJARAT) INDIA. MOBILE- 09428153344.

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[Guest guest]

Quality does not need quantity.

Hi all,

I am sure that those who participated actively in this discussion or

passively read the posts like me will agree that this discussion had

the depth of contents and our very dear moderator did wonderful work.

Compliments to Dr Bharat. Even though the formal thanks from the

NetRUM management team from India will be forthcoming, my greetings

from overseas.

Vijay from Boston

>

> Dear friends,

> Tomorrow is the last day of discussion.

> Somehow, I am not so happy with the discussion going on.Either

members are not having interest or failure on my part to generate

interest amongst members.Accepting second possibility and considering

lacuna on my part, I apologize the members.

>

> DR. BHARAT GAJJAR ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY,

PRAMUKHSWAMI MEDICAL COLLEGE, KARAMSAD-388325. DIST.-ANAND

(GUJARAT) INDIA. MOBILE- 09428153344.

>

[Guest guest]

Dear Dr Bharat, The discussion was good. We enjoyed it. Probably because of summer vacations, there are not many takers now a days. Congrats for a wonderful moderation. -AnupamaVijay <drvijaythawani@...> wrote: Quality does not need quantity.Hi all,I am sure that those who participated actively in this discussion orpassively read the posts like me will agree that this discussion hadthe depth of contents and our very dear moderator did wonderful

work.Compliments to Dr Bharat. Even though the formal thanks from theNetRUM management team from India will be forthcoming, my greetingsfrom overseas.Vijay from Boston>> Dear friends,> Tomorrow is the last day of discussion.> Somehow, I am not so happy with the discussion going on.Eithermembers are not having interest or failure on my part to generateinterest amongst members.Accepting second possibility and consideringlacuna on my part, I apologize the members.> > DR. BHARAT GAJJAR ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY,PRAMUKHSWAMI MEDICAL COLLEGE, KARAMSAD-388325. DIST.-ANAND(GUJARAT) INDIA. MOBILE- 09428153344.>

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[Guest guest]

Dear friends,

The current discussion is over now.

Thanks a lot to Dr. Vijay, Dr. Geer and Dr. Anupama for their kind words. They have boost up my moral with their words.

I agree with Vijay that the discussion was having depth of contents ( Credit goes to Dr.Geer and Dr.Anupama for their contributions). Anupama's point of 'summer vacation' is also valid.Thank you all.

DR. BHARAT GAJJAR

ASSOCIATE PROFESSOR,

DEPARTMENT OF PHARMACOLOGY,

PRAMUKHSWAMI MEDICAL COLLEGE,

KARAMSAD-388325.

DIST.-ANAND (GUJARAT) INDIA.

MOBILE- 09428153344.

Quality does not need quantity.Hi all,I am sure that those who participated actively in this discussion orpassively read the posts like me will agree that this discussion hadthe depth of contents and our very dear moderator did wonderful work.Compliments to Dr Bharat. Even though the formal thanks from theNetRUM management team from India will be forthcoming, my greetingsfrom overseas.Vijay from Boston>> Dear friends,> Tomorrow is the last day of discussion.> Somehow, I am not so happy with the discussion going on.Eithermembers are not having interest or failure on my part to generateinterest amongst members.Accepting second possibility and consideringlacuna on my part, I apologize the members.> > DR. BHARAT

GAJJAR ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY,PRAMUKHSWAMI MEDICAL COLLEGE, KARAMSAD-388325. DIST.-ANAND(GUJARAT) INDIA. MOBILE- 09428153344.>

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