Guest guest Posted April 28, 2011 Report Share Posted April 28, 2011 OSR#1 is an industrial chelator used to clean toxic soil. Absence of toxicity testing and being sold with drug claims is getting the manufacturer in trouble; in fact the toxicity in animal testing was withheld/minimised by the mfg. <http://leftbrainrightbrain.co.uk/2010/06/fda-warns-maker-of-osr-1/> If OSR#1 increases glutathione it operates by removal of metals as opposed to supporting the creation of glutathione by providing the necessary precursors. In other words the " rate-limiting " precursors for glutathione production are still necessary even while one is chelating. 200 genes involved in glutathione production can be switched on with sulforaphane, which is a safe and tested nutrient extracted from broccoli sprouts. all good, Duncan > > one option to increase glutahione is OSR1. check it out. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2011 Report Share Posted April 29, 2011 Yes, I know OSR has many uses. I mean, corn is also used to make car seats, and coconut to make cleaning agents. The mechanism you describe, OSR removing metals is one possibility, and the other actually fostering the additional production of glutathione. Nobody is sure. Anyway, I have used it, have also used dmsa/ALA. I think OSR is better. Just an option. There are many. The manufacturer got in trouble because the FDA determined this is a drug as opposed to a supplement, but OSR has a big following. Tsouderos is the writer behind the reported stories and has been criticized for her partiality. . > > > > one option to increase glutahione is OSR1. check it out. > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2011 Report Share Posted April 29, 2011 Thanks . I think nondisclosure of the toxicity of OSR#1 is a pretty big point, and if anyone knows how the manufacturer proposes the glutathione increase occurs, that would be of interest too. The reason is that several compounds provoke glutathione manufacture by challenge, for example bio-oxidative therapies briefly but hugely increase oxidative stress, resulting in an endogenous antioxidant response. An increase in oxidative stress should be met with an increase in precursors that can be applied against it, because low cyst(e)ine, the rate-limiting factor for glutahtione production, is pretty damaging. Increasing bonded cysteine is the " other half " of bio-oxidative therapy for this reason. all good, Duncan > > Yes, I know OSR has many uses. I mean, corn is also used to make car seats, and coconut to make cleaning agents. > > The mechanism you describe, OSR removing metals is one possibility, and the other actually fostering the additional production of glutathione. Nobody is sure. Anyway, I have used it, have also used dmsa/ALA. I think OSR is better. Just an option. There are many. > > The manufacturer got in trouble because the FDA determined this is a drug as opposed to a supplement, but OSR has a big following. Tsouderos is the writer behind the reported stories and has been criticized for her partiality. > > . > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2011 Report Share Posted April 29, 2011 I was reading to day that oxidative stress and inflammation cause the liver to release cortisol and which consequently decreases progesterone. The article was actually dealing with post inflammation from workouts or other strenuous activities. He said that systematic enzymes decrease inflammation and therefor protects depletion of progesterone, and consequently testosterone.Can you add some clarity to this?Olushola On Fri, Apr 29, 2011 at 2:09 PM, DuncanCrow <duncancrow@...> wrote: Â Thanks . I think nondisclosure of the toxicity of OSR#1 is a pretty big point, and if anyone knows how the manufacturer proposes the glutathione increase occurs, that would be of interest too. The reason is that several compounds provoke glutathione manufacture by challenge, for example bio-oxidative therapies briefly but hugely increase oxidative stress, resulting in an endogenous antioxidant response. An increase in oxidative stress should be met with an increase in precursors that can be applied against it, because low cyst(e)ine, the rate-limiting factor for glutahtione production, is pretty damaging. Increasing bonded cysteine is the " other half " of bio-oxidative therapy for this reason. all good, Duncan > > Yes, I know OSR has many uses. I mean, corn is also used to make car seats, and coconut to make cleaning agents. > > The mechanism you describe, OSR removing metals is one possibility, and the other actually fostering the additional production of glutathione. Nobody is sure. Anyway, I have used it, have also used dmsa/ALA. I think OSR is better. Just an option. There are many. > > The manufacturer got in trouble because the FDA determined this is a drug as opposed to a supplement, but OSR has a big following. Tsouderos is the writer behind the reported stories and has been criticized for her partiality. > > . > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 29, 2011 Report Share Posted April 29, 2011 200 genes involved in glutathione production can be switched on with sulforaphane, which is a safe and tested nutrient extracted from broccoli sprouts. What does gene switching mean? How can genes be selectively switched on? For example one doesn't want to switch on genes that are associated with maladies. Olushola Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 30, 2011 Report Share Posted April 30, 2011 A lot of work has been done recently to switch genes on or off exogenously, from outside the cell. Here's something on sulphoraphane and glutathione: http://tinyurl.com/glutathione-sulforaphane all good, Duncan > > > 200 genes involved in glutathione production can be switched on with > > sulforaphane, which is a safe and tested nutrient extracted from broccoli > > sprouts. > > > > What does gene switching mean? How can genes be selectively switched on? For > example one doesn't want to switch on genes that are associated with > maladies. > > Olushola > Quote Link to comment Share on other sites More sharing options...
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