Fibromyalgia Researcher

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Showing posts with label researchers and doctors. Show all posts Showing posts with label researchers and doctors. Show all posts Wednesday, March 14, 2007 Fibromyalgia Researcher Dr. M.B. Yunus on the Future of Fibromyalgia Research According to Essential Science Indicators, Dr. Muhammad B. Yunus is one of the most widely published fibromyalgia researchers, with 16 papers cited a total of 422 times as of late 2006. Dr. Yunus is Professor of Medicine in the Section of Rheumatology at the University of Illinois College of Medicine at Peoria. In an interview with Dr. Yunus from September 2006, he discusses his background in fibromyalgia research and then envisions the future of fibromyalgia research: A greater number of studies involving a large array of neurotransmitters involved in the pain pathway may be most relevant in fibromyalgia research in the future. There will be more drug studies involving many neurotransmitters, their receptors and subtypes. Serotonin, norepinephrine, dopamine, substance P, NMDA receptors and their subtypes,

among others, are likely targets of more fruitful research with better identification of agonists or inhibitors that will be helpful in developing new drugs without significant side-effects. Thus, research on the basic science of FMS and related syndromes may lead to discovery of new pharmacological agents for better treatment of the suffering patients (as has been the case with rheumatoid arthritis in recent years).Roles of ion channels and cytokines released from microglia and astrocytes need to be carefully investigated. Among the inhibitory pathways, the opioid system has so far not been studied earnestly. The effect of both pharmacological and non-pharmacological interventions on [central sensitization] can be tested in a human pain laboratory setting or by neuroimaging prior to their large scale clinical trials. Researchers should also focus on further genetic studies of FMS and other members of the [central sentivity syndromes] family.He

goes on to mention the necessity of more research into fatigue in FMS, an area that has rarely been studied. "Most likely a combination of endocrine abnormalities, dysfunction of certain areas of the [central nervous system] along with particular neurotransmitter abnormalities, as well as psychological distress are involved in causing fatigue, but we need data to prove this," Dr. Yunus says. He also mentions the dearth of information on the symptom of muscle stiffness, which he says is often not helped by common pain treatments, and the need for information about the origins and triggers of the syndrome. More studies are expected involving the factors that may trigger FMS... such as viral infection, mental and physical trauma, poor sleep, environmental factors (such as noise and chemicals) and various psychosocial stresses in childhood and their probable ability to cause long term neuronal plasticity among the adults.

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ah yes.. these are the pathways (especially substance P) that i hope we will see drug development... all the medications (including lyrica) are more sympotom management then going toward the source of the problem... of course since the cause of fibro isn't exactly know this is a problem, but there are starting to be very specific indications of differences in fibro where i hope to goodness drug develpment will occur in say 10 years nadine redman <nlraccount@...> wrote: Showing posts with label

researchers and doctors. Show all posts Showing posts with label researchers and doctors. Show all posts Wednesday, March 14, 2007 Fibromyalgia Researcher Dr. M.B. Yunus on the Future of Fibromyalgia Research According to Essential Science

Indicators, Dr. Muhammad B. Yunus is one of the most widely published fibromyalgia researchers, with 16 papers cited a total of 422 times as of late 2006. Dr. Yunus is Professor of Medicine in the Section of Rheumatology at the University of Illinois College of Medicine at Peoria. In an interview with Dr. Yunus from September 2006, he discusses his background in fibromyalgia research and then envisions the future of fibromyalgia research: A greater number of studies involving a large array of neurotransmitters involved in the pain pathway may be most relevant in fibromyalgia research in the future. There will be more drug studies involving many neurotransmitters, their receptors and subtypes. Serotonin, norepinephrine, dopamine, substance P, NMDA receptors and their subtypes, among others, are likely targets of more fruitful research with better

identification of agonists or inhibitors that will be helpful in developing new drugs without significant side-effects. Thus, research on the basic science of FMS and related syndromes may lead to discovery of new pharmacological agents for better treatment of the suffering patients (as has been the case with rheumatoid arthritis in recent years).Roles of ion channels and cytokines released from microglia and astrocytes need to be carefully investigated. Among the inhibitory pathways, the opioid system has so far not been studied earnestly. The effect of both pharmacological and non-pharmacological interventions on [central sensitization] can be tested in a human pain laboratory setting or by neuroimaging prior to their large scale clinical trials. Researchers should also focus on further genetic studies of FMS and other members of the [central sentivity syndromes] family.He goes on to mention the necessity of more research into fatigue in FMS,

an area that has rarely been studied. "Most likely a combination of endocrine abnormalities, dysfunction of certain areas of the [central nervous system] along with particular neurotransmitter abnormalities, as well as psychological distress are involved in causing fatigue, but we need data to prove this," Dr. Yunus says. He also mentions the dearth of information on the symptom of muscle stiffness, which he says is often not helped by common pain treatments, and the need for information about the origins and triggers of the syndrome. More studies are expected involving the factors that may trigger FMS... such as viral infection, mental and physical trauma, poor sleep, environmental factors (such as noise and chemicals) and various psychosocial stresses in childhood and their probable ability to cause long term neuronal plasticity among the adults. Never miss a thing. Make your homepage.

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STOP! STOP! STOP! Why can't you just accept that we all try to get through our days the best way we can? I mean OMG - treat the fibro and not the symptoms? There are many doctors who won't even acknowledge fibro exists let alone try to treat it. *sigh* I'm tired of this... please stop nadine redman <nlraccount@...> wrote: Showing posts with label researchers and doctors. Show all posts Showing posts with label researchers and doctors. Show all posts Wednesday, March

14, 2007 Fibromyalgia Researcher Dr. M.B. Yunus on the Future of Fibromyalgia Research According to Essential Science Indicators, Dr. Muhammad B. Yunus is one of the most widely published fibromyalgia researchers, with 16 papers cited a total of 422 times as of late 2006. Dr. Yunus is Professor of Medicine in the Section of Rheumatology at the University of Illinois College of Medicine at Peoria. In an interview with Dr. Yunus from September 2006, he discusses his background in fibromyalgia research

and then envisions the future of fibromyalgia research: A greater number of studies involving a large array of neurotransmitters involved in the pain pathway may be most relevant in fibromyalgia research in the future. There will be more drug studies involving many neurotransmitters, their receptors and subtypes. Serotonin, norepinephrine, dopamine, substance P, NMDA receptors and their subtypes, among others, are likely targets of more fruitful research with better identification of agonists or inhibitors that will be helpful in developing new drugs without significant side-effects. Thus, research on the basic science of FMS and related syndromes may lead to discovery of new pharmacological agents for better treatment of the suffering patients (as has been the case with rheumatoid arthritis in recent years).Roles of ion channels and cytokines released from microglia and astrocytes need to be carefully investigated. Among the inhibitory pathways,

the opioid system has so far not been studied earnestly. The effect of both pharmacological and non-pharmacological interventions on [central sensitization] can be tested in a human pain laboratory setting or by neuroimaging prior to their large scale clinical trials. Researchers should also focus on further genetic studies of FMS and other members of the [central sentivity syndromes] family.He goes on to mention the necessity of more research into fatigue in FMS, an area that has rarely been studied. "Most likely a combination of endocrine abnormalities, dysfunction of certain areas of the [central nervous system] along with particular neurotransmitter abnormalities, as well as psychological distress are involved in causing fatigue, but we need data to prove this," Dr. Yunus says. He also mentions the dearth of information on the symptom of muscle stiffness, which he says is often not helped by common pain treatments, and the need for information

about the origins and triggers of the syndrome. More studies are expected involving the factors that may trigger FMS... such as viral infection, mental and physical trauma, poor sleep, environmental factors (such as noise and chemicals) and various psychosocial stresses in childhood and their probable ability to cause long term neuronal plasticity among the adults. Never miss a thing. Make your homepage.

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Treatment for disease first begins with treating the symptoms. This is such a new disease that how can we just try to get through the days as best we can? Why not force the medical field in finding out what causes Fibro and find a way to fix it for good? What if people who first got ovarian cancer said STOP? What about J. Fox and his disease? He refuses to say STOP! He is determined to help find a cure, not just for himself but for millions of others. Are we so unlike them? in AZ <oriana_az@...> wrote: STOP! STOP! STOP! Why can't you just accept that we all try to get through our days the best way we can? I mean OMG - treat the fibro and not the symptoms? There are many doctors who won't even acknowledge fibro exists let alone try to treat it. *sigh* I'm tired of this... please stop nadine redman <nlraccount > wrote: Showing posts with label researchers and doctors. Show all posts Showing posts with label researchers and doctors. Show all posts Wednesday, March 14, 2007 Fibromyalgia Researcher Dr. M.B. Yunus on the Future of Fibromyalgia Research According to Essential Science Indicators, Dr. Muhammad B. Yunus is one of the most widely published fibromyalgia researchers, with 16 papers cited a total of 422 times as of late 2006. Dr. Yunus is Professor of Medicine in the Section of Rheumatology at the University of Illinois College of Medicine at Peoria. In an interview with Dr. Yunus from September 2006, he discusses his background in fibromyalgia research and then envisions the future of fibromyalgia research: A greater number of studies involving a large array of neurotransmitters involved in the pain pathway may be most relevant in fibromyalgia research in the future. There will be more drug studies involving many neurotransmitters, their receptors and subtypes. Serotonin, norepinephrine, dopamine, substance P, NMDA receptors and their subtypes,

among others, are likely targets of more fruitful research with better identification of agonists or inhibitors that will be helpful in developing new drugs without significant side-effects. Thus, research on the basic science of FMS and related syndromes may lead to discovery of new pharmacological agents for better treatment of the suffering patients (as has been the case with rheumatoid arthritis in recent years).Roles of ion channels and cytokines released from microglia and astrocytes need to be carefully investigated. Among the inhibitory pathways, the opioid system has so far not been studied earnestly. The effect of both pharmacological and non-pharmacological interventions on [central sensitization] can be tested in a human pain laboratory setting or by neuroimaging prior to their large scale clinical trials. Researchers should also focus on further genetic studies of FMS and other members of the [central sentivity syndromes] family.He

goes on to mention the necessity of more research into fatigue in FMS, an area that has rarely been studied. "Most likely a combination of endocrine abnormalities, dysfunction of certain areas of the [central nervous system] along with particular neurotransmitter abnormalities, as well as psychological distress are involved in causing fatigue, but we need data to prove this," Dr. Yunus says. He also mentions the dearth of information on the symptom of muscle stiffness, which he says is often not helped by common pain treatments, and the need for information about the origins and triggers of the syndrome. More studies are expected involving the factors that may trigger FMS... such as viral infection, mental and physical trauma, poor sleep, environmental factors (such as noise and chemicals) and various psychosocial stresses in childhood and their probable ability to cause long term neuronal plasticity among the adults. Never miss a thing. Make your homepage. Never miss a thing. Make your homepage.

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Okay but why don't you take your efforts to the media and to educate the public for awareness and their support, more support to get the research done that we need so badly to find treatments that actually work for most people rather than a few and try to find a cure as well. We all know everything you've said but the people who need to hear about it are not the sick ones, it's the healthy, normal people out there that need to hear what you are saying. I totally understand what in AZ is saying and she's correct, enough already!! Some of us have to do what we can each and every day. Everyone has their own way of dealing with it and you need to accept that. It's not that we don't want to find a cure but a lot of people don't have that kind of energy. But if you do, then great! It's time to address the media, the mayor of your city, the Governor and the president to get a new health care program, get funding for medical treatments and such. All we are saying is that the 'support' you are trying to offer, is not coming across as support, but rather criticizing others for how they deal with their pain and the day to day stuff. So please stop doing that. This group really does not need that. Please go complain to the healthy world and maybe with our combined efforts, we can actually make an actual impact. WhitneyOn Jan 12, 2008 8:51 PM, nadine redman <nlraccount@...> wrote:

Treatment for disease first begins with treating the symptoms. This is such a new disease that how can we just try to get through the days as best we can? Why not force the medical field in finding out what causes Fibro and find a way to fix it for good? What if people who first got ovarian cancer said STOP? What about J. Fox and his disease? He refuses to say STOP! He is determined to help find a cure, not just for himself but for millions of others. Are we so unlike them?

in AZ <oriana_az@...> wrote:

STOP! STOP! STOP! Why can't you just accept that we all try to get through our days the best way we can?

I mean OMG - treat the fibro and not the symptoms? There are many doctors who won't even acknowledge fibro exists let alone try to treat it.

*sigh* I'm tired of this... please stop

nadine redman <nlraccount@...> wrote: Showing posts with label researchers and doctors. Show all posts Showing posts with label researchers and doctors

.. Show all posts Wednesday, March 14, 2007

Fibromyalgia Researcher Dr. M.B. Yunus on the Future of Fibromyalgia Research

According to Essential Science Indicators, Dr. Muhammad B. Yunus is one of the most widely published fibromyalgia researchers, with 16 papers cited a total of 422 times as of late 2006. Dr. Yunus is Professor of Medicine in the Section of Rheumatology at the University of Illinois College of Medicine at Peoria. In an interview with Dr. Yunus from September 2006, he discusses his background in fibromyalgia research and then envisions the future of fibromyalgia research: A greater number of studies involving a large array of neurotransmitters involved in the pain pathway may be most relevant in fibromyalgia research in the future. There will be more drug studies involving many neurotransmitters, their receptors and subtypes. Serotonin, norepinephrine, dopamine, substance P, NMDA receptors and their subtypes,

among others, are likely targets of more fruitful research with better identification of agonists or inhibitors that will be helpful in developing new drugs without significant side-effects. Thus, research on the basic science of FMS and related syndromes may lead to discovery of new pharmacological agents for better treatment of the suffering patients (as has been the case with rheumatoid arthritis in recent years).

Roles of ion channels and cytokines released from microglia and astrocytes need to be carefully investigated. Among the inhibitory pathways, the opioid system has so far not been studied earnestly. The effect of both pharmacological and non-pharmacological interventions on [central sensitization] can be tested in a human pain laboratory setting or by neuroimaging prior to their large scale clinical trials. Researchers should also focus on further genetic studies of FMS and other members of the [central sentivity syndromes] family.

He

goes on to mention the necessity of more research into fatigue in FMS, an area that has rarely been studied. " Most likely a combination of endocrine abnormalities, dysfunction of certain areas of the [central nervous system] along with particular neurotransmitter abnormalities, as well as psychological distress are involved in causing fatigue, but we need data to prove this, " Dr. Yunus says. He also mentions the dearth of information on the symptom of muscle stiffness, which he says is often not helped by common pain treatments, and the need for information about the origins and triggers of the syndrome.

More studies are expected involving the factors that may trigger FMS... such as viral infection, mental and physical trauma, poor sleep, environmental factors (such as noise and chemicals) and various psychosocial stresses in childhood and their probable ability to cause long term neuronal plasticity among the adults.

Never miss a thing. Make your homepage.

Never miss a thing. Make your homepage.

Looking for last minute shopping deals? Find them fast with Search.

-- Eat, sleep, dream and be the music!Life is short, live each day to its' fullest!Cave softly and leave no trace.Find a cure for chronic pain!Ask about The Purrfect Petsitter and Infinite Creations!

[Guest guest]

I'm not criticizing people with how they deal with their disease. Wow.....this is crazy. You're right, I am going to see what I can do to get more people educated about Fibromyalgia. I was hoping someone else would want to start as well, in another state other than Ohio. You're right, everyone has their own way of dealing with this, and I do accept that, do you of mine? Do I have the energy? No, not at all. I have a very hard time with just doing what is expected of me. My life has been compromised greatly because of this stupid disease. I have had to drop out of college, forget my degree and try to figure out something else to do with my life. I have 2 teenagers that I try to make sure they have the "motherly support" that they need, and I have so many episodes of "forgetfulness" that luckily instead of getting angry they make it into kinda a joke thing and start sending me text

messages, etc., so I don't forget important things. Add on top of that the pain of Rheumatoid Arthritis, and it's anything but pleasant, but that's my world. Nadine Whitney <infinite242@...> wrote: Okay but why don't you take your efforts to the media and to educate the public for awareness and their support, more support to get the research done that we need so badly to find treatments that actually work for most people rather than a few and try to find a cure as well. We all

know everything you've said but the people who need to hear about it are not the sick ones, it's the healthy, normal people out there that need to hear what you are saying. I totally understand what in AZ is saying and she's correct, enough already!! Some of us have to do what we can each and every day. Everyone has their own way of dealing with it and you need to accept that. It's not that we don't want to find a cure but a lot of people don't have that kind of energy. But if you do, then great! It's time to address the media, the mayor of your city, the Governor and the president to get a new health care program, get funding for medical treatments and such. All we are saying is that the 'support' you are trying to offer, is not coming across as support, but rather criticizing others for how they deal with their pain and the day to day stuff. So please stop doing that. This group really does not need that. Please go complain to the healthy world and maybe with our

combined efforts, we can actually make an actual impact. Whitney On Jan 12, 2008 8:51 PM, nadine redman <nlraccount > wrote: Treatment for disease first begins with treating the symptoms. This is such a new disease that how can we just try to get through the days as best we can? Why not force the medical field in finding out what causes Fibro and find a way to fix it for good? What if people who first got ovarian cancer said STOP? What about J. Fox and his disease? He refuses to say STOP! He is determined to help find a cure, not just for himself but for millions of others. Are we so unlike them? in AZ <oriana_az > wrote: STOP! STOP! STOP! Why can't you just accept that we all try to get through our days the best way we can? I mean OMG - treat the fibro and not the symptoms? There are many doctors who won't even acknowledge fibro exists let alone try to treat it. *sigh* I'm tired of this... please stop nadine redman <nlraccount >

wrote: Showing posts with label researchers and doctors. Show all posts Showing posts with label researchers and doctors . Show all posts Wednesday, March 14, 2007 Fibromyalgia Researcher Dr. M.B. Yunus on the Future of Fibromyalgia Research According to Essential Science Indicators, Dr. Muhammad B. Yunus is one of the most widely

published fibromyalgia researchers, with 16 papers cited a total of 422 times as of late 2006. Dr. Yunus is Professor of Medicine in the Section of Rheumatology at the University of Illinois College of Medicine at Peoria. In an interview with Dr. Yunus from September 2006, he discusses his background in fibromyalgia research and then envisions the future of fibromyalgia research: A greater number of studies involving a large array of neurotransmitters involved in the pain pathway may be most relevant in fibromyalgia research in the future. There will be more drug studies involving many neurotransmitters, their receptors and subtypes. Serotonin, norepinephrine, dopamine, substance P, NMDA receptors and their subtypes, among others, are likely targets of more fruitful research with better identification of agonists or inhibitors that will be

helpful in developing new drugs without significant side-effects. Thus, research on the basic science of FMS and related syndromes may lead to discovery of new pharmacological agents for better treatment of the suffering patients (as has been the case with rheumatoid arthritis in recent years). Roles of ion channels and cytokines released from microglia and astrocytes need to be carefully investigated. Among the inhibitory pathways, the opioid system has so far not been studied earnestly. The effect of both pharmacological and non-pharmacological interventions on [central sensitization] can be tested in a human pain laboratory setting or by neuroimaging prior to their large scale clinical trials. Researchers should also focus on further genetic studies of FMS and other members of the [central sentivity syndromes] family. He goes on to mention the necessity of more research into fatigue in FMS, an area that has rarely been studied. "Most likely

a combination of endocrine abnormalities, dysfunction of certain areas of the [central nervous system] along with particular neurotransmitter abnormalities, as well as psychological distress are involved in causing fatigue, but we need data to prove this," Dr. Yunus says. He also mentions the dearth of information on the symptom of muscle stiffness, which he says is often not helped by common pain treatments, and the need for information about the origins and triggers of the syndrome. More studies are expected involving the factors that may trigger FMS... such as viral infection, mental and physical trauma, poor sleep, environmental factors (such as noise and chemicals) and various psychosocial stresses in childhood and their probable ability to cause long term neuronal plasticity among the adults. Never miss a thing. Make your homepage. Never miss a thing. Make your homepage. Looking for last minute shopping deals? Find them fast with Search. -- Eat, sleep, dream and be the music!Life is short, live each day to its' fullest!Cave softly and leave no trace.Find a cure for chronic pain!Ask about The Purrfect Petsitter and Infinite Creations!

Looking for last minute shopping deals? Find them fast with Search.