Guest guest Posted March 22, 2008 Report Share Posted March 22, 2008 Passing along a response from a member who did more research on this topic… I find the very last sentence interesting since I have had meningitis so many times… Shari Ferbert www.AFFTER.org From: Sherry W 'Shari Ferbert' Subject: RE: Press release: Cortisol in CFS and FM Hi Shari Just wanted to show you a few things I found on a couple of sites. Nothing specific about FMS but it does say things that indicate that cortisol could be a factor in FMS. It has been said that FMS comes from some form of a stressful situation and the section highlighted gives some indication. I have also been told that those who have both autoimmune and FMS that the autoimmune develops first that FMS doesn’t develop before an autoimmune disease. Below states that low levels of cortisol can develop from some autoimmune disease. The last thing I found was from Mayo Clinic about meningitis complications and this is something I have seen in my research on FMS that it could be caused from viral, bacterial, or fungal infections. So with this information from Mayo you could say it is a possibility of low cortisol as the problem. I had been told at least 5 years ago from my doctor that it is a hormonal disorder but because of the cost of treatment it isn’t a option for most people because insurance won’t cover it. Now it is coming out that the problem is hormonal but they haven’t pin pointed it. Just a bit of information from me but I would be interested if anyone else has been told that it is hormonal from their Doctor. I will ask my Rheumatologist what she think about it unfortunately my other Dr. isn’t practicing so I can’t ran it pass him he was the one who said it was hormonal. Thanks for all the great information and have a wonderful Easter, Sherry ********************** High values A high level of cortisol in the blood can mean Cushing's syndrome, a disorder that can be caused by overactive adrenal glands, a pituitary or adrenal gland tumor, some types of cancer, or long-term use of corticosteroids. One cause of Cushing's syndrome is Cushing's disease, a condition caused by a noncancerous tumor of the pituitary gland (adenoma). An adenoma causes the pituitary gland to make too much of the hormone adrenocorticotropic hormone (ACTH), which in turn causes the adrenal glands to make too much cortisol. A high blood cortisol level can be caused by severe liver or kidney disease, depression, hyperthyroidism, or obesity .. Conditions such as recent surgery, illness, injury, or whole-body infection (sepsis) can cause high cortisol levels. Low values A low level of cortisol in the blood can mean 's disease, which is caused by damage to the adrenal glands. If the pituitary gland is not working well, it can cause low levels of the hormone ACTH, which in turn causes low levels of cortisol. Symptoms of pituitary gland failure are like those of 's disease. Conditions that can damage the adrenal glands or pituitary gland include some infections, head injury, and some autoimmune diseases. A low level of cortisol can be caused by internal bleeding that leads to shock. For example, severe bleeding during childbirth that causes damage to the pituitary gland of the mother (Sheehan's syndrome) can cause a low level of blood cortisol. http://www.webmd.com/a-to-z-guides/cortisol-14668 Post-traumatic Stress Disorder Causes When you are afraid, your body activates the " fight or flight " response —a reference to our caveman ancestors facing a tiger. In reaction, your body releases adrenaline, which is responsible for increasing blood pressure and heart rate and increasing glucose to muscles (to allow you to run away quickly in the face of immediate danger). However, once the immediate danger (which may or may not have actually existed) is gone, the body begins a process of shutting down the stress response, and this process involves the release of another hormone known as cortisol. If your body does not generate enough cortisol to shut down the flight or stress reaction, you may continue to feel the stress effects of the adrenaline. Trauma victims who develop post-traumatic stress disorder often have higher levels of other stimulating hormones (catecholamines) under normal conditions in which the threat of trauma is not present. These same hormones kick in when they are reminded of their trauma. Physically, your body also increases your heart rate. After a month in this heightened state, with stress hormones elevated, you may develop further physical changes, such as heightened hearing. This cascade of physical changes, one triggering another, suggests that early intervention may be the key to heading off the effects of post-traumatic stress disorder. http://www.webmd.com/mental-health/post-traumatic-stress-disorder Meningitis - Non-neurological complications may include kidney failure and adrenal gland failure. Your adrenal glands produce a number of important hormones including cortisol, which helps your body deal with stress. This was from Mayo clinic ################################################# Quote Link to comment Share on other sites More sharing options...
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