Re: Cholesterol and its SubFractions

[Guest guest]

>>Does everyone here have an indepth understanding of this important

topic? I want to know a LOT more about it so please anyone that may have

more information please share it here.

This is a great resource for Online Medical textbooks. I am sure you

will find what you want in these. I would try bio-chemisty ones first.

http://daly.medicine.iu.edu/ebooks.asp

Jeff

[Guest guest]

Hi Freebird:

This is JW's favorite source for much stuff:

http://books.nap.edu/books/0309085373/html/433.html#pagetop

Rodney.

>

> A few posts back I asked for any comprehensive

> references/web-sites/articles even recent books etc on cholesterol.

I

> post this request again becuase I thought it may have gotten lost in

> rest of message.

>

> Does everyone here have an indepth understanding of this important

> topic? I want to know a LOT more about it so please anyone that may

> have more information please share it here.

>

> TIA.

[Guest guest]

Hi Freebird:

This too:

http://www.lescolxl.com/NCEP_Flashcard.pdf

Rodney.

>

> A few posts back I asked for any comprehensive

> references/web-sites/articles even recent books etc on cholesterol.

I

> post this request again becuase I thought it may have gotten lost in

> rest of message.

>

> Does everyone here have an indepth understanding of this important

> topic? I want to know a LOT more about it so please anyone that may

> have more information please share it here.

>

> TIA.

[Guest guest]

Hi Freebird:

Third, no one in the Framingham study with total cholesterol under

150 has ever had a heart attack; and WUSTL study subjects, who had

been on CRON for three or more years, averaged total cholesterol of

157 (and also had a whole lot of other equally, or even more,

impressive CVD markers).

So, based on risk factors, heart disease would appear to be next to

irrelevant to anyone, including many in this group (although not me,

quite yet) who are established as fully on CRON (as measured by

BMI/BF%/WCtoH/caloric intake etc). Similarly diabetes.

At least that is the way it would seem.

Rodney.

>

> A few posts back I asked for any comprehensive

> references/web-sites/articles even recent books etc on cholesterol.

I

> post this request again becuase I thought it may have gotten lost in

> rest of message.

>

> Does everyone here have an indepth understanding of this important

> topic? I want to know a LOT more about it so please anyone that may

> have more information please share it here.

>

> TIA.

[Guest guest]

>>Third, no one in the Framingham study with total cholesterol under 150

has ever had a heart attack;

On a lighter note, someone once said... " that's because there was no one

in the framingham study who had a cholesterol of under 150 "

Regards

Jeff

[Guest guest]

What bugs me about Framingham and other epidemiological studies is

that you get one thing right (low LDL making you safe from CHD) but

then you die of a stroke or some other cause at the same rate. It

seems balance is the best, not too high LDL and not too low LDL.

Although what is too low and what is the balance ?

" Based on six years of follow-up evaluations of the Framingham,

Mass, men and women aged 49 to 82 years, it was found that a low-

density lipoprotein (LDL) cholesterol concentration was associated

with a low incidence of coronary heart disease (CHD) risk but with a

statistically significant excess of stroke incidence in women and of

deaths from non-CHD causes in both sexes. There was no suggestion

that an elevated HDL cholesterol level was associated with an excess

incidence of any of the cardiovascular end points considered or of

death. "

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

holding=npg & cmd=Retrieve & db=PubMed & list_uids=7259370 & dopt=Abstract

(pubmed 7259370)

richard ...

[Guest guest]

Typically, people who don't have heart attacks, may have CHF, or cancer, or ischemic stroke, and if they live long enough hemo stroke, finally pneumonia. This article is 23 yrs old.

What's the concensus statement from the AHA today?

IMO, best is to get TC ~150, maybe less, then sweat the subfractions, because it's not easy to adjust subfractions.

----- Original Message -----

From: rwalkerad1970

Sent: Saturday, November 13, 2004 5:29 AM

Subject: [ ] Re: Cholesterol and its SubFractions

What bugs me about Framingham and other epidemiological studies is that you get one thing right (low LDL making you safe from CHD) but then you die of a stroke or some other cause at the same rate. It seems balance is the best, not too high LDL and not too low LDL. Although what is too low and what is the balance ?"Based on six years of follow-up evaluations of the Framingham, Mass, men and women aged 49 to 82 years, it was found that a low-density lipoprotein (LDL) cholesterol concentration was associated with a low incidence of coronary heart disease (CHD) risk but with a statistically significant excess of stroke incidence in women and of deaths from non-CHD causes in both sexes. There was no suggestion that an elevated HDL cholesterol level was associated with an excess incidence of any of the cardiovascular end points considered or of death."http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?holding=npg & cmd=Retrieve & db=PubMed & list_uids=7259370 & dopt=Abstract (pubmed 7259370)richard ...

[Guest guest]

Hi :

That is a VERY old study. And have you (and did it) take acount of

the following?:

A) As we all know, heart disease accounts for a very large

proportion of total deaths.

Most people die of something eventually.

C) So, those who, by their nutrition behaviour, manage to pretty

much eliminate the, by far, largest cause of death, will obviousy die

very much more often than the average from all the OTHER causes.

Perhaps that is taken account of in that study. Perhaps it isn't.

But certainly one can readily imagine that clogged arteries are much

less likely to spring a leak than clean ones. Likely true also of

clogged water pipes.

In addition, there are things one can do to reduce the incidence of

these other problems. Studies come out daily these days showing that

so-and-so behaviour increases/decreases the risk of this-or-that

disease.

But face it. You are not likely to get out of this life alive ;

^ )))

Rodney.

>

> What bugs me about Framingham and other epidemiological studies is

> that you get one thing right (low LDL making you safe from CHD) but

> then you die of a stroke or some other cause at the same rate. It

> seems balance is the best, not too high LDL and not too low LDL.

> Although what is too low and what is the balance ?

>

> " Based on six years of follow-up evaluations of the Framingham,

> Mass, men and women aged 49 to 82 years, it was found that a low-

> density lipoprotein (LDL) cholesterol concentration was associated

> with a low incidence of coronary heart disease (CHD) risk but with

a

> statistically significant excess of stroke incidence in women and

of

> deaths from non-CHD causes in both sexes. There was no suggestion

> that an elevated HDL cholesterol level was associated with an

excess

> incidence of any of the cardiovascular end points considered or of

> death. "

>

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

> holding=npg & cmd=Retrieve & db=PubMed & list_uids=7259370 & dopt=Abstract

>

> (pubmed 7259370)

>

>

> richard ...