Guest guest Posted October 22, 2004 Report Share Posted October 22, 2004 It was UNFILTERED coffee that was associated with the increased risks. So throw out your French press coffeepot, and you should be OK. Theoretically. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2004 Report Share Posted October 22, 2004 Here is abstract of that coffee study.. I don't see where they made any distinction b/w filtered and unfiltered. http://www.ajcn.org/cgi/content/abstract/80/4/862 Associations between coffee consumption and inflammatory markers in healthy persons: the ATTICA study1,2,3 Antonis Zampelas, Demosthenes B Panagiotakos, Christos Pitsavos, Chrysohoou and Christodoulos Stefanadis 1 From the Department of Nutrition and Dietetics, Harokopio University, Athens, Greece (AZ and DBP); and the First Cardiology Clinic, School of Medicine, University of Athens, Greece (CP, CC, and CS). Background: The effect of coffee consumption on the cardiovascular system is conflicting. Inflammation is important to the development of cardiovascular disease (CVD), and several dietary factors are thought to exert significant effects on inflammation and thus on the risk of CVD. Objective: We aimed to investigate the associations between coffee consumption and inflammatory markers. Design: The cross-sectional survey enrolled 1514 men ( ± SD age: 46 ± 13 y; range: 18–87 y) and 1528 women (aged 45 ± 13 y; range: 18–89 y). Five percent of men and 3% of women were excluded for history of CVD. Fasting blood samples were collected. Dietary habits (including consumption of various types of coffee) were evaluated by using a validated food-frequency questionnaire. Results: Compared with coffee nondrinkers, men who consumed >200 mL coffee/d had 50% higher interleukin 6 (IL-6), 30% higher C-reactive protein (CRP), 12% higher serum amyloid-A (SAA), and 28% higher tumor necrosis factor (TNF-) concentrations and 3% higher white blood cell (WBC) counts (all: P < 0.05). Women who consumed >200 mL coffee/d had 54% higher IL-6, 38% higher CRP, 28% higher SAA, and 28% higher TNF- concentrations and 4% higher WBC counts (all: P < 0.05) than did coffee nondrinkers. The findings were significant even after control for the interactions between coffee consumption and age, sex, smoking, body mass index, physical activity status, and other covariates. Conclusions: A relation exists between moderate-to-high coffee consumption and increased inflammation process. This relation could explain, in part, the effect of increased coffee intake on the cardiovascular system. Key Words: Inflammation • cardiovascular disease • risk factors • coffee --- In , " Cyn " <cynthialstern@m...> wrote: > > It was UNFILTERED coffee that was associated with the increased > risks. > > So throw out your French press coffeepot, and you should be OK. > > Theoretically. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2004 Report Share Posted October 22, 2004 Quote from the original cited article: " The report did not identify which coffee ingredients caused the increased risk but Prof Zampelas said the suspicion was that cafestol and kahweol, found in unfiltered coffee, were to blame. " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2004 Report Share Posted October 22, 2004 Hi : Well where do you get that information from? The article only says that it is *suspected* that that is the source of the problem: " Prof Zampelas said the suspicion was that cafestol and kahweol, found in unfiltered coffee, were to blame. " This study had a fairly large number of subjects. What proportion of the population drinks unfiltered coffee? Fairly low I would have thought. So a smallish proportion of the population drinking unfiltered coffee is supposed to cause a noticeable effect on the data for the entire sample? If that is the case then cafestol and kahweol must be pretty nasty stuff. Maybe. But maybe not. Since the phenomenon is noticeable in the entire sample perhaps it is some other component? No doubt we will know in a couple of years. I drink coffee. But not lots of it. Rodney. --- In , " Cyn " <cynthialstern@m...> wrote: > > It was UNFILTERED coffee that was associated with the increased > risks. > > So throw out your French press coffeepot, and you should be OK. > > Theoretically. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 22, 2004 Report Share Posted October 22, 2004 > > Here is abstract of that coffee study.. I don't see where they made > any distinction b/w filtered and unfiltered. > > http://www.ajcn.org/cgi/content/abstract/80/4/862 > Associations between coffee consumption and inflammatory markers in > healthy persons: the ATTICA study1,2,3 > Antonis Zampelas, Demosthenes B Panagiotakos, Christos Pitsavos, > Chrysohoou and Christodoulos Stefanadis > 1 From the Department of Nutrition and Dietetics, Harokopio > University, Athens, Greece (AZ and DBP); and the First Cardiology > Clinic, School of Medicine, University of Athens, Greece (CP, CC, and > CS). > > > Background: The effect of coffee consumption on the cardiovascular > system is conflicting. Inflammation is important to the development > of cardiovascular disease (CVD), and several dietary factors are > thought to exert significant effects on inflammation and thus on the > risk of CVD. > > Objective: We aimed to investigate the associations between coffee > consumption and inflammatory markers. > > Design: The cross-sectional survey enrolled 1514 men ( ± SD age: 46 ± > 13 y; range: 18–87 y) and 1528 women (aged 45 ± 13 y; range: 18–89 > y). Five percent of men and 3% of women were excluded for history of > CVD. Fasting blood samples were collected. Dietary habits (including > consumption of various types of coffee) were evaluated by using a > validated food-frequency questionnaire. > > Results: Compared with coffee nondrinkers, men who consumed >200 mL > coffee/d had 50% higher interleukin 6 (IL-6), 30% higher C-reactive > protein (CRP), 12% higher serum amyloid-A (SAA), and 28% higher tumor > necrosis factor (TNF-) concentrations and 3% higher white blood cell > (WBC) counts (all: P < 0.05). Women who consumed >200 mL coffee/d had > 54% higher IL-6, 38% higher CRP, 28% higher SAA, and 28% higher TNF- > concentrations and 4% higher WBC counts (all: P < 0.05) than did > coffee nondrinkers. The findings were significant even after control > for the interactions between coffee consumption and age, sex, > smoking, body mass index, physical activity status, and other > covariates. > > Conclusions: A relation exists between moderate-to-high coffee > consumption and increased inflammation process. This relation could > explain, in part, the effect of increased coffee intake on the > cardiovascular system. Hi All, For your interest is the following, for which the pdf is available. I would have categorized the curve as reverse-L- Shaped for the all-cause mortality, which to me is the bottom line. Arch Intern Med. 2000 Dec 11-25;160(22):3393-400. Coffee consumption and the risk of coronary heart disease and death. Kleemola P, Jousilahti P, Pietinen P, Vartiainen E, Tuomilehto J. .... coronary heart disease (CHD) ... 20 179 randomly selected eastern Finnish men and women aged 30 to 59 years who participated in a cross-sectional risk factor survey in 1972, 1977, or 1982. ... followed up for 10 years ... Multivariate analyses were performed by using the proportional hazards model. RESULTS: In men, the risk of nonfatal myocardial infarction was not associated with coffee drinking. The age-adjusted association of coffee drinking was J shaped with CHD mortality and U shaped with all-cause mortality. The highest CHD mortality was found among those who did not drink coffee at all (multivariate adjusted). Also, in women, all-cause mortality decreased by increasing coffee drinking. The prevalence of smoking and the mean level of serum cholesterol increased with increasing coffee drinking. Non- coffee drinkers more often reported a history of various diseases and symptoms, and they also more frequently used several drugs compared with coffee drinkers. CONCLUSIONS: Coffee drinking does not increase the risk of CHD or death. In men, slightly increased mortality from CHD and all causes in heavy coffee drinkers is largely explained by the effects of smoking and a high serum cholesterol level. PMID: 11112231 [PubMed - indexed for MEDLINE] The amount of all-cause death due to coffee, where 1 cup = 100 mg caffeine, was: Cups, value (confidence interval) < 1, 1.58 (1.20-2.07) 1-3, 1.00 4-7, 0.97 (0.82-1.14) > 7, 1.01 (0.84-1.22) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2004 Report Share Posted October 23, 2004 Hi All, I have always held the view that coffee drinking is more or less neutral in its all-cause death, which to me is the bottom line. This seems to be the overall finding in the literature, irrespective of our weight, as an indicator of our level of CR. For evidence, see: 1: Jazbec A, Simic D, Corovic N, Durakovic Z, Pavlovic M. Impact of coffee and other selected factors on general mortality and mortality due to cardiovascular disease in Croatia. J Health Popul Nutr. 2003 Dec;21(4):332-40. PMID: 15038588 [PubMed - indexed for MEDLINE] 2: Iwai N, Ohshiro H, Kurozawa Y, Hosoda T, Morita H, Funakawa K, Okamoto M, Nose T. Relationship between coffee and green tea consumption and all-cause mortality in a cohort of a rural Japanese population. J Epidemiol. 2002 May;12(3):191-8. PMID: 12164320 [PubMed - indexed for MEDLINE] 3: Kleemola P, Jousilahti P, Pietinen P, Vartiainen E, Tuomilehto J. Coffee consumption and the risk of coronary heart disease and death. Arch Intern Med. 2000 Dec 11-25;160(22):3393-400. PMID: 11112231 [PubMed - indexed for MEDLINE] 4: Woodward M, Tunstall-Pedoe H. Coffee and tea consumption in the ish Heart Health Study follow up: conflicting relations with coronary risk factors, coronary disease, and all cause mortality. J Epidemiol Community Health. 1999 Aug;53(8):481-7. PMID: 10562866 [PubMed - indexed for MEDLINE] 5: Fraser GE. Associations between diet and cancer, ischemic heart disease, and all-cause mortality in non-Hispanic white California Seventh-day Adventists. Am J Clin Nutr. 1999 Sep;70(3 Suppl):532S-538S. PMID: 10479227 [PubMed - indexed for MEDLINE] 6: JB, Annegers JF, Curb JD, Heyden S, Howson C, Lee ES, Lee M. Mortality patterns among hypertensives by reported level of caffeine consumption. Prev Med. 1988 May;17(3):310-20. PMID: 3043418 [PubMed - indexed for MEDLINE] Now, it seems, along comes an article that may be less relevant, since it is an epidemiology study. CR purportedly reduces inflammation and its markers. Yet the pdf-available below implies coffee counters at least inflammation markers: Am J Clin Nutr 2004;80:862–7. Associations between coffee consumption markers in healthy persons: the ATTICA Antonis Zampelas, Demosthenes B Panagiotakos, Christos Christodoulos Stefanadis ... cardiovascular disease (CVD) ... to investigate the associations between coffee consumption and inflammatory markers. ... 1514 men (SD age: 46 ... and 1528 women (aged 45 y ... food-frequency questionnaire. Results: Compared with coffee nondrinkers, men who consumed >200 mL coffee/d had 50% higher interleukin 6 (IL-6), 30% higher C-reactive protein (CRP), 12% higher serum amyloid-A (SAA), and 28% higher tumor necrosis factor(TNF) concentrations and 3% higher white blood cell (WBC) counts (all: P < 0.05). Women who consumed >200 mL coffee/d had 54% higher IL-6, 38% higher CRP, 28% higher SAA, and 28% higher TNF concentrations and 4% higher WBC counts (all: P <0.05) than did coffee nondrinkers. The findings were significant even after control for the interactions between coffee consumption and age, sex, smoking, body mass index, physical activity status, and other covariates. Conclusions: A relation exists between moderate-to-high coffee consumption and increased inflammation process. ... Cheers, Alan Pater > > > > It was UNFILTERED coffee that was associated with the increased > > risks. > > > > So throw out your French press coffeepot, and you should be OK. > > > > Theoretically. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2004 Report Share Posted October 23, 2004 Hi : So to clarify, are you saying that the results of the greek study may only apply to Greece because a much higher proportion of the coffee drunk in Greece is unfiltered? Thanks. Rodney. > > > > > > Here is abstract of that coffee study.. I don't see > > where they made > > > any distinction b/w filtered and unfiltered. > > > > > > http://www.ajcn.org/cgi/content/abstract/80/4/862 > > > Associations between coffee consumption and > > inflammatory markers in > > > healthy persons: the ATTICA study1,2,3 > > > Antonis Zampelas, Demosthenes B Panagiotakos, Christos > > Pitsavos, > > > Chrysohoou and Christodoulos Stefanadis > > > 1 From the Department of Nutrition and Dietetics, > > Harokopio > > > University, Athens, Greece (AZ and DBP); and the First > > Cardiology > > > Clinic, School of Medicine, University of Athens, > > Greece (CP, CC, > > and > > > CS). > > > > > > > > > Background: The effect of coffee consumption on the > > cardiovascular > > > system is conflicting. Inflammation is important to the > > development > > > of cardiovascular disease (CVD), and several dietary > > factors are > > > thought to exert significant effects on inflammation > > and thus on > > the > > > risk of CVD. > > > > > > Objective: We aimed to investigate the associations > > between coffee > > > consumption and inflammatory markers. > > > > > > Design: The cross-sectional survey enrolled 1514 men ( > > ± SD age: 46 > > ± > > > 13 y; range: 18–87 y) and 1528 women (aged 45 ± 13 y; > > range: 18–89 > > > y). Five percent of men and 3% of women were excluded > > for history > > of > > > CVD. Fasting blood samples were collected. Dietary > > habits > > (including > > > consumption of various types of coffee) were evaluated > > by using a > > > validated food-frequency questionnaire. > > > > > > Results: Compared with coffee nondrinkers, men who > > consumed >200 mL > > > coffee/d had 50% higher interleukin 6 (IL-6), 30% > > higher C-reactive > > > protein (CRP), 12% higher serum amyloid-A (SAA), and > > 28% higher > > tumor > > > necrosis factor (TNF-) concentrations and 3% higher > > white blood > > cell > > > (WBC) counts (all: P < 0.05). Women who consumed >200 > > mL coffee/d > > had > > > 54% higher IL-6, 38% higher CRP, 28% higher SAA, and > > 28% higher TNF- > > > > > concentrations and 4% higher WBC counts (all: P < 0.05) > > than did > > > coffee nondrinkers. The findings were significant even > > after > > control > > > for the interactions between coffee consumption and > > age, sex, > > > smoking, body mass index, physical activity status, and > > other > > > covariates. > > > > > > Conclusions: A relation exists between moderate-to-high > > coffee > > > consumption and increased inflammation process. This > > relation could > > > explain, in part, the effect of increased coffee intake > > on the > > > cardiovascular system. > > > > Hi All, > > > > For your interest is the following, for which the pdf > > is available. > > > > I would have categorized the curve as reverse-L- > > Shaped for the all-cause mortality, which to me is > > the bottom line. > > > > Arch Intern Med. 2000 Dec 11-25;160(22):3393-400. > > Coffee consumption and the risk of coronary heart disease > > and death. > > Kleemola P, Jousilahti P, Pietinen P, Vartiainen E, > > Tuomilehto J. > > > > ... coronary heart disease (CHD) ... 20 179 randomly > > selected eastern Finnish men and women aged 30 to 59 > > years who > > participated in a > > cross-sectional risk factor survey in 1972, 1977, or > > 1982. ... > > followed up for 10 > > years ... Multivariate analyses were performed by using > > the > > proportional > > hazards model. RESULTS: In men, the risk of nonfatal > > myocardial > > infarction was > > not associated with coffee drinking. The age-adjusted > > association of > > coffee > > drinking was J shaped with CHD mortality and U shaped > > with all-cause > > mortality. > > The highest CHD mortality was found among those who did > > not drink > > coffee at all > > (multivariate adjusted). Also, in women, all-cause > > mortality > > decreased by > > increasing coffee drinking. The prevalence of smoking and > > the mean > > level of > > serum cholesterol increased with increasing coffee > > drinking. Non- > > coffee drinkers > > more often reported a history of various diseases and > > symptoms, and > > they also > > more frequently used several drugs compared with coffee > > drinkers. > > CONCLUSIONS: > > Coffee drinking does not increase the risk of CHD or > > death. In men, > > slightly > > increased mortality from CHD and all causes in heavy > > coffee drinkers > > is largely > > explained by the effects of smoking and a high serum > > cholesterol > > level. > > > > PMID: 11112231 [PubMed - indexed for MEDLINE] > > > > The amount of all-cause death due to coffee, where 1 cup > > = 100 mg > > caffeine, was: > > Cups, value (confidence interval) > > < 1, 1.58 (1.20-2.07) > > 1-3, 1.00 > > 4-7, 0.97 (0.82-1.14) > > > 7, 1.01 (0.84-1.22) > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.