Re: Sibling versus parent heart disease heart disease prediction

[Guest guest]

A person has more in common with their siblings than with each parent. This

is because a parent only supplies 50% of the genetic makeup to each of their

offspring. But you and your siblings have derived 100% of your genes from

the same genetic pool. Thus you are most closely related to your siblings

(genetically) than anyone else, including your children.

on 10/6/2004 1:15 PM, old542000 at apater@... wrote:

>

> Hi All,

>

> Dad clearly had heart diseases, so the below URL from the CBC caught

> my eye. The heart risk factor initiated my interest eventually in

> CR, due to high cholesterol and irregular heart beat that I had.

>

> Siblings having heart disease versus parents having heart disease

> seems to be a better indication for our heart disease prediction.

>

> I was surprised to read:

>

> http://www.cbc.ca/story/science/national/2004/10/05/heart_sibs041005.h

> tml

>

> I do not understand the indications from the genetics point of view.

>

> Of course, my siblings have not been vigorously examined as were the

> study subjects, but several have shared my heart disease risks that

> are easily determined. An angiogram, many of the sophisticated

> measurements done in the WUSTL studies and various other measurements

> showed that I was free of all indications of heart disease and its

> risks.

>

> I checked the 5 October issue of Circulation and found no such paper.

>

> Al Pater.

[Guest guest]

Hi folks:

Also, siblings eating habits must be very nearly identical - they eat

from the same batches of prepared food until they leave home.

But dietary circumstances when their parents were younger may have

been very different from those when the kids are around. Immigrants

from many countries will have had radically different diets (probably

a lot healthier!) when they were kids in those other countries,

compared with those of their kids in the US. Especially in the case

of those who emigrate from poorer countries.

Rodney.

>

> >

> > Hi All,

> >

> > Dad clearly had heart diseases, so the below URL from the CBC

caught

> > my eye. The heart risk factor initiated my interest eventually in

> > CR, due to high cholesterol and irregular heart beat that I had.

> >

> > Siblings having heart disease versus parents having heart disease

> > seems to be a better indication for our heart disease prediction.

> >

> > I was surprised to read:

> >

> >

http://www.cbc.ca/story/science/national/2004/10/05/heart_sibs041005.h

> > tml

> >

> > I do not understand the indications from the genetics point of

view.

> >

> > Of course, my siblings have not been vigorously examined as were

the

> > study subjects, but several have shared my heart disease risks

that

> > are easily determined. An angiogram, many of the sophisticated

> > measurements done in the WUSTL studies and various other

measurements

> > showed that I was free of all indications of heart disease and its

> > risks.

> >

> > I checked the 5 October issue of Circulation and found no such

paper.

> >

> > Al Pater.

[Guest guest]

Ah ha, the old " nature vs. nurture " argument. It appears both are very

powerful influences.

While I've never heard the argument that siblings are better predictors due

to more similar genome it sounds reasonable. However for that benefit we

forfeit several decades of historical data to pull from.

I suggest shaking our family tree to see what's likely to kill us and take

appropriate action based on what the data tells us. Why don't we just

combine the history of both parents for risk analysis? At worst we'll over

protect.

Life is a simultaneous equation with many variables. Too many to easily

optimize but we need to try to keep an eye on as many as we can to keep them

in check.

JR

PS: I've already buried a younger sibling with cancer + so the tree limbs

have fallen close enough for me to get the message.

-----Original Message-----

From: Rodney [mailto:perspect1111@...]

Sent: Wednesday, October 06, 2004 12:55 PM

Subject: [ ] Re: Sibling versus parent heart disease heart

disease prediction

Hi folks:

Also, siblings eating habits must be very nearly identical - they eat

from the same batches of prepared food until they leave home.

But dietary circumstances when their parents were younger may have

been very different from those when the kids are around. Immigrants

from many countries will have had radically different diets (probably

a lot healthier!) when they were kids in those other countries,

compared with those of their kids in the US. Especially in the case

of those who emigrate from poorer countries.

Rodney.

[Guest guest]

--- In , " " <crjohnr@b...>

wrote:

> > I've already buried a younger sibling with cancer + so the tree

limbs

> have fallen close enough for me to get the message.

I have also, All, a younger brother at his 31-year-old age.

Cheers, Al.

[Guest guest]

Hi All,

The article used the singular form of parent. We derive all our

genetic information from our parents. Our siblings have the same

situation, and the title of the article said " brother " .

> A person has more in common with their siblings than with each

parent. This

> is because a parent only supplies 50% of the genetic makeup to each

of their

> offspring. But you and your siblings have derived 100% of your

genes from

> the same genetic pool. Thus you are most closely related to your

siblings

> (genetically) than anyone else, including your children.

>

>

>

[Guest guest]

Hi All,

We emigrated from Holland to Canada and the diets of our parents are

much worse than are our diets.

Yes, the diets of sibings are more alike than are our diets compared

with those of our parents.

Cheers, Al Pater.

--- In , " Rodney " <perspect1111@y...>

wrote:

>

> Hi folks:

>

> Also, siblings eating habits must be very nearly identical - they

eat

> from the same batches of prepared food until they leave home.

>

> But dietary circumstances when their parents were younger may have

> been very different from those when the kids are around.

Immigrants

> from many countries will have had radically different diets

(probably

> a lot healthier!) when they were kids in those other countries,

> compared with those of their kids in the US. Especially in the

case

> of those who emigrate from poorer countries.